HYALURONIC ACID IN TREATMENT OF KNEE OSTEOARTHRITIS



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Abstract

Osteoarthritis is an important medical and social problem. Оsteoarthritis affects 13% of the adult population in Russia. Knee and hip joints are affected most frequently. Оsteoarthritis therapy includes nonpharmacologic and pharmacologic methods. Hyaluronic acid is widely used in the treatment of osteoarthritis in recent years. Intraarticular injections of hyaluronic acid more effective than placebo, are not inferior to traditional treatments and can be used as a symptomatic treatment of OA. Local therapy with hyaluronic acid well tolerated, reduces pain and improves function. Intraarticular injections of hyaluronic acid used in patients with knee OA stages I-III, less than 65 years of age, in patients who do not respond adequately to conventional therapy or with contraindications to nonsteroidal anti-inflammatory drugs (NSAIDs). Hyaluronic acid preparations of different molecular weight are of comparable effectiveness. Repeated courses do not increase the risk of side effects.

About the authors

N V Vaskova

Ural State Medical University

O M Lesnyak

North-Western State Medical University named after I. I. Mechnikov

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Copyright (c) 2014 Vaskova N.V., Lesnyak O.M.

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