Malignant arterial hypertension in a child with nonspecific aortoarteritis

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Abstract

The article presents a clinical case of malignant renovascular hypertension in a child, resulting from non-specific aortoarteritis. The disease initially manifested with abdominal pain and convulsions, leading to hospitalization. During the hospital stay, blood pressure readings were elevated to 180/100 mmHg and higher. Over the course of a year, the patient underwent pathogenetic (immunosuppressive), combined (triple) antihypertensive treatment, and symptomatic therapy. Due to the malignant nature of the hypertension, progression of organ damage, a high risk of complications and mortality, and the ineffectiveness of conservative treatment, surgical interventions were performed.

The first stage involved polyposition abdominal aortography and stent-graft implantation in the abdominal aorta. Despite restored blood flow in the abdominal aorta, blood pressure remained elevated over the following three months, even with ongoing antihypertensive therapy. As a result, a nephrectomy was performed at the second stage. Postoperatively, the patient’s blood pressure significantly decreased to 130/90–120/80 mmHg. Antihypertensive therapy was continued to reach lower target blood pressure values.

Non-specific aortoarteritis remains a prognostically unfavorable condition, even after reconstructive surgery, owning to its autoimmune nature, which suggests ongoing arterial inflammation even during clinical remission. This necessitates lifelong monitoring by a rheumatologist.

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About the authors

Rayhan S. Maytbasova

Scientific Center of Pediatrics and Pediatric Surgery

Author for correspondence.
Email: rmaytbasova@mail.ru
ORCID iD: 0000-0001-6319-4998

MD, Dr. Sci. (Med.), Professor

Kazakhstan, Almaty

Zhanar Zh. Nurgaliyeva

Scientific Center of Pediatrics and Pediatric Surgery; Asfendiyarov Kazakh National Medical University

Email: nurgaliyeva.z@kaznmu.kz
ORCID iD: 0000-0003-0490-8000
SPIN-code: 3485-6245

MD, Cand. Sci. (Medicine)

Kazakhstan, Almaty; Almaty

Gulmira E. Erzhanova

Scientific Center of Pediatrics and Pediatric Surgery

Email: fortune_9@mail.ru
Kazakhstan, Almaty

Aziz K. Onlasynov

Scientific Center of Pediatrics and Pediatric Surgery

Email: onlassynov@mail.ru
Kazakhstan, Almaty

Bahytzhan D. Abekenov

Scientific Center of Pediatrics and Pediatric Surgery

Email: abekenov.urolog@mail.ru
ORCID iD: 0000-0002-7661-3933

MD, Cand. Sci. (Medicine)

Kazakhstan, Almaty

Galymzhan T. Abuov

Scientific Center of Pediatrics and Pediatric Surgery

Email: galymzhan_abuov@mail.ru
Kazakhstan, Almaty

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