Malignant arterial hypertension in a child with nonspecific aortoarteritis
- Authors: Maytbasova R.S.1, Nurgaliyeva Z.Z.1,2, Erzhanova G.E.1, Onlasynov A.K.1, Abekenov B.D.1, Abuov G.T.1
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Affiliations:
- Scientific Center of Pediatrics and Pediatric Surgery
- Asfendiyarov Kazakh National Medical University
- Issue: Vol 28, No 3 (2024)
- Pages: 66-73
- Section: Case report
- Submitted: 09.07.2024
- Accepted: 29.07.2024
- Published: 13.10.2024
- URL: https://journals.eco-vector.com/RFD/article/view/634145
- DOI: https://doi.org/10.17816/RFD634145
- ID: 634145
Cite item
Abstract
The article presents a clinical case of malignant renovascular hypertension in a child, resulting from non-specific aortoarteritis. The disease initially manifested with abdominal pain and convulsions, leading to hospitalization. During the hospital stay, blood pressure readings were elevated to 180/100 mmHg and higher. Over the course of a year, the patient underwent pathogenetic (immunosuppressive), combined (triple) antihypertensive treatment, and symptomatic therapy. Due to the malignant nature of the hypertension, progression of organ damage, a high risk of complications and mortality, and the ineffectiveness of conservative treatment, surgical interventions were performed.
The first stage involved polyposition abdominal aortography and stent-graft implantation in the abdominal aorta. Despite restored blood flow in the abdominal aorta, blood pressure remained elevated over the following three months, even with ongoing antihypertensive therapy. As a result, a nephrectomy was performed at the second stage. Postoperatively, the patient’s blood pressure significantly decreased to 130/90–120/80 mmHg. Antihypertensive therapy was continued to reach lower target blood pressure values.
Non-specific aortoarteritis remains a prognostically unfavorable condition, even after reconstructive surgery, owning to its autoimmune nature, which suggests ongoing arterial inflammation even during clinical remission. This necessitates lifelong monitoring by a rheumatologist.
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About the authors
Rayhan S. Maytbasova
Scientific Center of Pediatrics and Pediatric Surgery
Author for correspondence.
Email: rmaytbasova@mail.ru
ORCID iD: 0000-0001-6319-4998
MD, Dr. Sci. (Med.), Professor
Kazakhstan, AlmatyZhanar Zh. Nurgaliyeva
Scientific Center of Pediatrics and Pediatric Surgery; Asfendiyarov Kazakh National Medical University
Email: nurgaliyeva.z@kaznmu.kz
ORCID iD: 0000-0003-0490-8000
SPIN-code: 3485-6245
MD, Cand. Sci. (Medicine)
Kazakhstan, Almaty; AlmatyGulmira E. Erzhanova
Scientific Center of Pediatrics and Pediatric Surgery
Email: fortune_9@mail.ru
Kazakhstan, Almaty
Aziz K. Onlasynov
Scientific Center of Pediatrics and Pediatric Surgery
Email: onlassynov@mail.ru
Kazakhstan, Almaty
Bahytzhan D. Abekenov
Scientific Center of Pediatrics and Pediatric Surgery
Email: abekenov.urolog@mail.ru
ORCID iD: 0000-0002-7661-3933
MD, Cand. Sci. (Medicine)
Kazakhstan, AlmatyGalymzhan T. Abuov
Scientific Center of Pediatrics and Pediatric Surgery
Email: galymzhan_abuov@mail.ru
Kazakhstan, Almaty
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