Malignant arterial hypertension in a child with nonspecific aortoarteritis

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The article presents a clinical case of malignant renovascular hypertension in a child, resulting from non-specific aortoarteritis. The disease initially manifested with abdominal pain and convulsions, leading to hospitalization. During the hospital stay, blood pressure readings were elevated to 180/100 mmHg and higher. Over the course of a year, the patient underwent pathogenetic (immunosuppressive), combined (triple) antihypertensive treatment, and symptomatic therapy. Due to the malignant nature of the hypertension, progression of organ damage, a high risk of complications and mortality, and the ineffectiveness of conservative treatment, surgical interventions were performed.

The first stage involved polyposition abdominal aortography and stent-graft implantation in the abdominal aorta. Despite restored blood flow in the abdominal aorta, blood pressure remained elevated over the following three months, even with ongoing antihypertensive therapy. As a result, a nephrectomy was performed at the second stage. Postoperatively, the patient’s blood pressure significantly decreased to 130/90–120/80 mmHg. Antihypertensive therapy was continued to reach lower target blood pressure values.

Non-specific aortoarteritis remains a prognostically unfavorable condition, even after reconstructive surgery, owning to its autoimmune nature, which suggests ongoing arterial inflammation even during clinical remission. This necessitates lifelong monitoring by a rheumatologist.

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作者简介

Rayhan Maytbasova

Scientific Center of Pediatrics and Pediatric Surgery

编辑信件的主要联系方式.
Email: rmaytbasova@mail.ru
ORCID iD: 0000-0001-6319-4998

MD, Dr. Sci. (Med.), Professor

哈萨克斯坦, Almaty

Zhanar Nurgaliyeva

Scientific Center of Pediatrics and Pediatric Surgery; Asfendiyarov Kazakh National Medical University

Email: nurgaliyeva.z@kaznmu.kz
ORCID iD: 0000-0003-0490-8000
SPIN 代码: 3485-6245

MD, Cand. Sci. (Medicine)

哈萨克斯坦, Almaty; Almaty

Gulmira Erzhanova

Scientific Center of Pediatrics and Pediatric Surgery

Email: fortune_9@mail.ru
哈萨克斯坦, Almaty

Aziz Onlasynov

Scientific Center of Pediatrics and Pediatric Surgery

Email: onlassynov@mail.ru
哈萨克斯坦, Almaty

Bahytzhan Abekenov

Scientific Center of Pediatrics and Pediatric Surgery

Email: abekenov.urolog@mail.ru
ORCID iD: 0000-0002-7661-3933

MD, Cand. Sci. (Medicine)

哈萨克斯坦, Almaty

Galymzhan Abuov

Scientific Center of Pediatrics and Pediatric Surgery

Email: galymzhan_abuov@mail.ru
哈萨克斯坦, Almaty

参考

  1. Onen F, Akkoc N. Epidemiology of Tacayasu arteritis. Presse Med. 2017;46(7-8 Pt 2):e197–e203. doi: 10.1016/j.lpm.2017.05.034
  2. Aeschlimann F, Yeung R, Laxer R. An update on childhood-onset Takayasu arteritis. Front Pediatr. 2022;10:872313. doi: 10.3389/fped.2022.872313
  3. Geppe NA, Podchernyaevoi NS, Lyskina GA, editors. Systemic Vasculitides. Handbook of Pediatric Rheumatology. Moscow: GEOTAR-Media; 2011. P. 507–599. (In Russ.) EDN: QLZLMT
  4. Kostina YuO, Lyskina GA, Oldakovsky VI. Features of the course of nonspecific aortoarteritis in children depending on the timing of diagnosis and the nature of basic therapy. Pediatriya. Zhurnal im G.N. Speranskogo. 2011;90(5):45–49. (In Russ.) EDN: OGHGXD
  5. Mossberg M, Segelmark M, Kahn R, et al. Epidemiology of primary systemic vasculitis in children: a population-based study from southern Sweden. Scand J Rheumatol. 2018:47:295–302. doi: 10.1080/03009742.2017.1412497
  6. Jang SY, Seo SR, Park SW, Kim DK. Prevalence of Takayasu’s arteritis in Korea. Clin Exp Rheumatol. 2018;36(Suppl 111):163–164.
  7. Numano F, Kobayashi Y. Takayasu arteritis — beyond pulselessness. Intern Med. 1999;38(3):226–232. doi: 10.2169/internalmedicine.38.226
  8. Li L, Zhou F, Li F, et al. Prevalence of tuberculosis infection among patients with Takayasu arteritis: a meta-analysis of observational studies. Sci Rep. 2023;13:22481. doi: 10.1038/s41598-023-49998-y
  9. Lyskina GA, Uspenskaya EV. Clinical picture, diagnostics and treatment of nonspecific aortoarteritis in children. Pediatriya. Consilium Medicum. 2008;2(10):14–19. (In Russ.) EDN: RNBJEF
  10. Lyskina GA, Kostina YuO. Nonspecific aortoarteritis: problems of complex therapy and evaluation of its effectiveness. Pediatriya. Zhurnal im G.N. Speranskogo. 2012;91(5):22–27. (In Russ.) EDN: PHFUFR
  11. Goncharova NS, Samokhvalova MV, Pakhomov AV. Takayasu arterıtıs: a revıew. Arterıal’naya gıpertenzıya. 2013;19(6):478–486. EDN: RWEJEX
  12. Flynn JT, Kaelber DC, Baker-Smith CM, et al. Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics. 2017;140(3):e20171904. doi: 10.1542/peds.2017-1904
  13. Vachev AN, Sukhorakov W, Frolova EV. Management of a hypertensive young adult suffering from nonspecific aortoarteritis accompanied by renal arterial lesions. Angiology and vascular surgery. Journal named after academician A.V. Pokrovsky. 2011;17(4):148–151. EDN: OPCJOF
  14. Forbes TJ, Gowda ST. Intravascular stent therapy for coarctation of the aorta. Methodist Debakey Cardiovasc J. 2014;10(2):82–87. doi: 10.14797/mdcj-10-2-82
  15. Márquez-González H, De León-Mena S, Yáñez-Gutiérrez L, et al. Late complications of aortic coarctationtreatment:amexican cohort study with more than 10-year follow-up. Revista Mexicana de Cardiologia. 2015;26(4):169–173.
  16. Maitbasova RS, Yerzhanova GE, Onlasynov AK, et al. Vasorenal arterial hypertension in a child with non-specific aortoartheritis. Pediatriya. Zhane bala khirurgiyasy. 2021;(1(103):54–59. EDN: OOXTSS

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