Molecular basis of applying antimutagens as anticarcinogens

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Abstract


The paper presents a review of current data on mechanisms of natural and synthetic antimutagen action underlying the expediency and availability of their application as anticarcinogens. Previously, some molecular processes involved in carcinogenesis as well as some therapeutic targets are considered. The effects of antimutagens on those or other molecular targets have been summarized in table. Along with the literature data on plant antimutagens, some experimental results and supposed mechanisms of the 1,4-dihydropyridine derivatives have been analyzed.

About the authors

Roza I Goncharova

Institute of Genetics and Cytology of the NASB, Minsk, Republic of Belarus

Email: R.Goncharova@igc.bas-net.by

Tatyana D Kuzhir

Institute of Genetics and Cytology of the NASB, Minsk, Republic of Belarus

Email: T.Kuzhir@igc.bas-net.by

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