Effect of genital endometriosis on fertility and gestation course

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Abstract

Hypothesis/aims of study. Endometriosis is a multifactorial, chronic and recurring condition that has a multifaceted negative impact on women’s fertility. The aim of the study was to assess the effect of genital endometriosis on the female reproductive system and pregnancy using the literature.

Study design, materials and methods. The review was performed by analyzing the articles published mainly over the last 5 years and deposited in PubMed Central, ScienceDirect, and Cyberleninka bibliographic databases.

Results. Current data for the management of patients with endometriosis, pathogenetic and pathophysiological mechanisms of infertility, and complications arising during pregnancy in patients with endometriosis are presented in this review article.

Conclusion. In patients with endometriosis, individualized management of the disease, full periconceptional multivitamin supplementation and the developed strategy of prenatal care should be taken to overcome infertility and to prevent or minimize the risk of complications associated with pregnancy.

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About the authors

Maria I. Yarmolinskaya

The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott; North-Western State Medical University named after I.I. Mechnikov

Email: m.yarmolinskaya@gmail.com
ORCID iD: 0000-0002-6551-4147
SPIN-code: 3686-3605
Scopus Author ID: 7801562649

MD, PhD, DSci (Medicine), Professor, Professor of the Russian Academy of Sciences, Head of the Department of Gynecology and Endocrinology, Head of the Diagnostics and Treatment of Endometriosis Center; Professor. The Department of Obstetrics and Gynecology

Russian Federation, Saint Petersburg

Chimnaz I. Seyidova

The Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott

Author for correspondence.
Email: seidov_46@mail.ru
ORCID iD: 0000-0002-6800-8661

resident physician

Russian Federation, Saint Petersburg

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