Email this article TIME-LAPSE technology in modern embryological practice
- Authors: Ishchuk M.A.1, Lesik E.A.1, Sagurova Y.M.1, Komarova E.M.1
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Affiliations:
- The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 72, No 6 (2023)
- Pages: 193-201
- Section: Theory and Practice
- Submitted: 13.10.2023
- Accepted: 03.11.2023
- Published: 15.12.2023
- URL: https://journals.eco-vector.com/jowd/article/view/609504
- DOI: https://doi.org/10.17816/JOWD609504
- ID: 609504
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Abstract
This article describes the basic principles of TIME-LAPSE technology. We report the use of this technology in modern embryological practice and compare it with the conventional cultivation system. Herein, we overview modern incubators equipped with the TIME-LAPSE system, including domestic ones, with their advantages and disadvantages listed. The main events of early human embryo development are described and rare events noted, such as abnormal pronucleus formation and disappearance, multinucleation of blastomeres, reverse cleavage, or “direct cleavage” into three blastomeres, which can only be visualized using TIME-LAPSE technology, but not with traditional visual assessment of embryo morphology. The use of artificial intelligence in conjunction with TIME-LAPSE technology for objective assessment and ranking of embryos based on their morphokinetic characteristics is given a thorough consideration. In conclusion, the article presents data on the impact of using technology on the effectiveness of IVF programs. Moreover, we herein describe such unobvious advantages of the TIME-LAPSE system as the ability to train and transfer video data between participants in the IVF protocol.
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About the authors
Mariia A. Ishchuk
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: mashamazilina@gmail.com
ORCID iD: 0000-0002-4443-4287
SPIN-code: 1237-6373
Russian Federation, Saint Petersburg
Elena A. Lesik
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: lesike@yandex.ru
ORCID iD: 0000-0003-1611-6318
SPIN-code: 6102-4690
Cand. Sci. (Biol.)
Russian Federation, Saint PetersburgYanina M. Sagurova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: yanina.sagurova96@mail.ru
ORCID iD: 0000-0003-4947-8171
SPIN-code: 8908-7033
Russian Federation, Saint Petersburg
Evgeniia M. Komarova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: evgmkomarova@gmail.com
ORCID iD: 0000-0002-9988-9879
SPIN-code: 1056-7821
Cand. Sci. (Biol.)
Russian Federation, Saint PetersburgReferences
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