Vol 62, No 5 (2013)

There was made a comparative analysis of surgical complications, life quality of patients and also sexual life quality after the correction of genital prolapse with the implants Prosima™ and Prolift™. There were reflected the advantages of the operation when the implants Prosima™ were used while correcting the genital prolapsed of III stage compared with the use of the implant Prolift™. There was shown the success of the operation Prosima™, its safety because of little invasiveness and few number of complications, satisfaction of the patients with the results of the treatment and also the improvement of the life quality and restoration of sexual activity.

Use of the method liquid-based cytology with next immunocytochemical study of endometrium is expedient for the differential diagnosis of endometrial pathology processes. The level of the gene PTEN and steroid receptors expression is higher in cases of simple hyperplasia and hyperplasia without atypia. Increase of the markers p53 and Ki67 expression was found only by atypical endometrial hyperplasia. Positive reaction on CD138 determines the inflammatory process.

The article considers the influence of combined oral contraceptives on size and function of thyroid gland in women of reproductive age. We examined 215 women, taking low dose and microdose combined oral contraceptives for 12 months as monotherapy or in combination with potassium iodide. The first group consisted of 75 women with diffuse nontoxic goiter, second – of 70 women with autoimmune thyroiditis. Control group consisted of 70 women without pathology of thyroid gland. Prior to therapy with combined contraceptives and after 12 months of treatment, we determined serum levels of free triiodothyronine, free thyroxine, and thyrotropin releasing hormone, antibodies to thyroid peroxidase and antibodies to thyroglobulin (ELISA) and performed sonography of thyroid gland. Results of our study suggest that combined oral contraceptives may increase the size of thyroid gland among women with diffuse nontoxic goiter without changing its function. In women with autoimmune thyroiditis, application of combined oral contraceptive significantly decreases blood levels of autoantibodies to thyroid peroxidase and thyroglobulin. Application of combined oral contraceptives in healthy women doesn’t influence the size and function of thyroid gland.

Photodynamic therapy (PDT) is defined as minimally invasive technique of the treatment of uterine cervix diseases associated with human papillomavirus (HPV). It is a method of choice in the patients of reproductive age. The monitoring of red fluorescence after the injection of photosensitizer during PDT provides the opportunity of control over the beginning of laser irradiation and its duration.

The role of endocrine factors in general maintenance of female sexuality in different ages, sexual dysfunctions associated with endocrine disorders, their treatment and preventive measures are considered in the article. The attention was also concentrated to the effects of oral contraception and therapy with oestrogen and testosteron for women sexuality.