Vol 62, No 5 (2013)

Articles
Modern concepts of epidemiologyHPV-infection
Semenova K.Y., Khachaturyan A.R.
Abstract
Human papillomavirus (HPV) is widespread sexually transmitted infection, which is defined by high risk of contagion and high cancer potential. HPV extension depends on patiens age, residence, opportunites of diagnostics, etc. There are general methods of HPV-diagnostics such as HPV DNA testing, cytological, hystological methods, which are not always useful in detection of transitory and persistent HPV-infection forms. Nowadays, there is acute need to develop new diagnostic and prognostic methods, treatment strategies for patients from various age groups, having different infection formss.
Journal of obstetrics and women's diseases. 2013;62(5):3-14
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Comparative assessment Of life quality of patients after the correction of genital prolapse with different synthetic implants
Bezhenar V.F., Guseva Y.S., Tsypurdeyeva A.A., Rusina Y.I., Tsuladze L.K.
Abstract
There was made a comparative analysis of surgical complications, life quality of patients and also sexual life quality after the correction of genital prolapse with the implants Prosima™ and Prolift™. There were reflected the advantages of the operation when the implants Prosima™ were used while correcting the genital prolapsed of III stage compared with the use of the implant Prolift™. There was shown the success of the operation Prosima™, its safety because of little invasiveness and few number of complications, satisfaction of the patients with the results of the treatment and also the improvement of the life quality and restoration of sexual activity.
Journal of obstetrics and women's diseases. 2013;62(5):15-28
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Efficiency of gonadotropin-releasing hormone analogue in endometriosis therapy
Denisova V.M.
Abstract
Endometriosis is estrogen- dependent disease. Aromatase P450 is the key enzyme in estrogen biosynthesis. The aim of the study was to compare therapeutic efficiency of gonadotropin-releasing hormone analogue (aGnRH) with ovarian aromatase activity. 64 women with endometriosis were examined after laparoscopic coagulation of endometrioid lesions. The examination included determination of FSH, LH, prolactin, antimüllerian hormone, estradiol, estrone and androstendione by immune-enzyme assay in peripheral blood and determination of ovarian aromatase activity by test with aromatase inhibitor letrozole. Laparoscopic coagulation of endometrioid lesions and following six- month course of aGnRH have lead to decrease of clinical manifestations of the disease and recovery of normal ovulatory menstrual cycle in most (72.5 %) of the patients. Therapeutic efficiency of combined therapy did not depend on basal blood estradiol level and ovarian aromatase activity.
Journal of obstetrics and women's diseases. 2013;62(5):29-34
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Immunocytochemistry in diagnostics of endometrial precancer
Dzyubiy T.I., Protasova A.E., Raskin G.A., Tsypurdeyeva A.A., Tapilskaya N.I.
Abstract
Use of the method liquid-based cytology with next immunocytochemical study of endometrium is expedient for the differential diagnosis of endometrial pathology processes. The level of the gene PTEN and steroid receptors expression is higher in cases of simple hyperplasia and hyperplasia without atypia. Increase of the markers p53 and Ki67 expression was found only by atypical endometrial hyperplasia. Positive reaction on CD138 determines the inflammatory process.
Journal of obstetrics and women's diseases. 2013;62(5):35-40
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Sigmovaginoplasty in patients with syndrome testicular feminization
Komyakov B.K., Guliyev B.G., Bezhenar V.F.
Abstract
The paper describes a case of a successful sigmovaginoplasty in patients with testicular feminization syndrome
Journal of obstetrics and women's diseases. 2013;62(5):41-44
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Hormonal contraception in women with diffuse nontoxic goiter and autoimmune thyroiditis
Pologoyko G.P.
Abstract
The article considers the influence of combined oral contraceptives on size and function of thyroid gland in women of reproductive age. We examined 215 women, taking low dose and microdose combined oral contraceptives for 12 months as monotherapy or in combination with potassium iodide. The first group consisted of 75 women with diffuse nontoxic goiter, second – of 70 women with autoimmune thyroiditis. Control group consisted of 70 women without pathology of thyroid gland. Prior to therapy with combined contraceptives and after 12 months of treatment, we determined serum levels of free triiodothyronine, free thyroxine, and thyrotropin releasing hormone, antibodies to thyroid peroxidase and antibodies to thyroglobulin (ELISA) and performed sonography of thyroid gland. Results of our study suggest that combined oral contraceptives may increase the size of thyroid gland among women with diffuse nontoxic goiter without changing its function. In women with autoimmune thyroiditis, application of combined oral contraceptive significantly decreases blood levels of autoantibodies to thyroid peroxidase and thyroglobulin. Application of combined oral contraceptives in healthy women doesn’t influence the size and function of thyroid gland.
Journal of obstetrics and women's diseases. 2013;62(5):45-51
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Laparoscopic diagnostics and treatment of acute early adhesive small bowel obstruction after gynecological operations performed by laparoscopic access
Timofeyev M.Y., Shtyrov S.V., Marchenko I.P., Kretsu V.N., Shapovalyants S.G.
Abstract
The Results of treatment of 8 female patients with early acute adhesive small bowel obstruction (AASBO) after laparoscopic gynecological surgery are presented. Diagnostic laparoscopy appeared to be the most helpful and the safest diagnostic technique, confirming the AASBO diagnosis and helping to choose operative treatment mode. In 5 patients AASBO was successfully treated using laparoscopic method, while in 3 patient median laparotomy was required: 1 patient with AASBO relapse, and 2 patients with pelvic peritonitis progression.
Journal of obstetrics and women's diseases. 2013;62(5):52-58
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Fluorescence monitoring photodynamic therapy of benign of the uterine cervix diseases associated with human papillomavirus
Khachaturyan A.R., Papayan G.V., Petrishchev N.N.
Abstract
Photodynamic therapy (PDT) is defined as minimally invasive technique of the treatment of uterine cervix diseases associated with human papillomavirus (HPV). It is a method of choice in the patients of reproductive age. The monitoring of red fluorescence after the injection of photosensitizer during PDT provides the opportunity of control over the beginning of laser irradiation and its duration.
Journal of obstetrics and women's diseases. 2013;62(5):59-65
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Vaginal microbiota at physiological microbiocenosis and with bacterial vaginosis
Nazarova V.V.
Abstract
The article presents literature review on the problem of bacterial vaginosis, describes current methods used for bacterial vaginosis diagnosis. Especial attention is spared for peculiarities vaginal microbiota at physiological microbiocenosis and with bacterial vaginosis.
Journal of obstetrics and women's diseases. 2013;62(5):66-74
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Endocrinology of women sexual health
Fedorova A.I.
Abstract
The role of endocrine factors in general maintenance of female sexuality in different ages, sexual dysfunctions associated with endocrine disorders, their treatment and preventive measures are considered in the article. The attention was also concentrated to the effects of oral contraception and therapy with oestrogen and testosteron for women sexuality.
Journal of obstetrics and women's diseases. 2013;62(5):75-84
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Surgical treatment of the patients with tubal infertility using endoscopic and microsurgical methods
Yakovleva N.V., Marinkin I.O.
Abstract
There are the results of the surgical treatment of 1257 patients with tubal infertility. It was demonstrated that surgical interventions with endo- and video-support are the most effective in the case of patients with distal occlusion of the fallopian tubes and proximal occlusion associated to the synechiae, little polyps, foreign substances. Microsurgical intervention is the method of choice in patients with real fibroid occlusion in the proximal tubes.
Journal of obstetrics and women's diseases. 2013;62(5):85-90
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