Myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage (clinical case)

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Abstract

Myelinated retinal nerve fibres are a rare, benign and asymptomatic lesion that is detected incidentally at fundus examination. In some cases, they may be associated with various abnormalities of the eye or have a complicated course. The article presents a clinical case of myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage.

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About the authors

Anastasiya N. Panfilova

Ophthalmological center “Vision”

Email: panfilova@zrenie.spb.ru
ORCID iD: 0000-0002-8191-6090

ophthalmologist

Russian Federation, Saint Petersburg

Taisiia A. Doktorova

S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch; North-Western State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: taisiiadok@mail.ru
ORCID iD: 0000-0003-2162-4018
SPIN-code: 8921-9738

postgraduate student, ophthalmologis

Russian Federation, Saint Petersburg; Saint Petersburg

Aleksei A. Suetov

S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch; State Scientific Research Test Institute of Military Medicine

Email: ophtalm@mail.ru
ORCID iD: 0000-0002-8670-2964
SPIN-code: 4286-6100

МD, Cand. Sci. (Med.), ophthalmologist, senior research associate

Russian Federation, Saint Petersburg; Saint Petersburg

References

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2. Fig. 1. Color fundus photography of a patient with myelinated nerve fibers complicated by vascular abnormalities (explanations in the text): a — general view, resolving vitreous hemorrhage (black arrows), laser burns after panretinal photocoagulation (blue arrows); b — myelinated retinal nerve fibers area with retino-vitreal neovascularization (arrow); c — structural OCT scan through the corresponding area; d, e — horizontal and vertical structural OCT scans through the center of the macula, in the fovea lamellar hole, epiretinal fibrosis, myelinated retinal nerve fibers extending into the fovea

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3. Fig. 2. Retinal fluorescein angiography data of a female patient with myelinated retinal fibers complicated by vascular abnormalities (explanations in the text): a — fundus image; b–d — hyperfluorescence of a fine, microvascular network with telangiectasias and neovascularization with signs of leakage in the late venous phase

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4. Fig. 3. Retinal fluorescein angiography data of the female patient with myelinated retinal fibers complicated by vascular abnormalities 3 months after intravitreal injection of ranibizumab (explanations in the text): a — fundus image; b–d — partial regression of the neovascularization and reduction of leakage

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