Vol 21, No 4 (2013)

Articles
Causes of length of conotruncus of embryonic mouse heart at normal condition and under the maternal dehydration
Dyagovets K.I., Tverdokhleb I.V.
Abstract
This work presents the histogenetic transformation from conotruncus of embryonic mouse heart (С57BL/6) under the normal and experimental condition. It was establish the reason of the shortening of the conotruncus of embryonic heart was delayed physiological proliferative activity of the cells of myocardial cuff during our research.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):7-11
views
Immunohistochemical characteristics age transformation of the cell phone mastoid brain people of different sex
Pavlov A.V., Saveljev S.V.
Abstract
Age-related changes in the structure of the human brain mamillary bodies were found in different age and sex. In elderly and senile age there is a decrease of GFAP-immunopositive cells. This process leads to an involutive transformations of neurons in the appropriate age. From 45 years of age in the mamillary bodies NSE-immunopositive cells are located around blood vessels in both sexes. Such an arrangement may be due to age-related changes in hemodynamics this structure. Reducing the number of MBP-immunopositive fibers in the elderly explains violation of synaptic connections both within the mamillary bodies and beyond. The observed changes in the expression of selected neuronal markers indicate age involution of mamillary bodies in both sexes.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):12-16
views
Morphological characteristics and features in sertoli cell ultrastructure experimental varicocele
Pivtorak V.I., Smiyukha O.A.
Abstract
Established anatomical morphometric characteristics of Sertoli cells in the simulation of varicocele and after treatment. After modeling varicocele perimeter and diameter of the cells and their nuclei was significantly decreased with increasing periods of varicocele. After undergoing surgery to Ivanissevich increased performance area, perimeter and diameter of Sertoli cells and their nuclei, but not enough to normalize their function. Forming operation between veins microvascular anastomosis using the method gives better results Sertoli cell regeneration compared to traditional obstructive operations because it normalizes the nuclear-cytoplasmic ratio and thereby creating more favorable conditions for the restoration of spermatogenic function.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):17-23
views
Morpholology of immune system of offspring after stimulation of maternal immune system in early pregnancy
Yaglova N.V., Obernikhin S.S.
Abstract
Stimulation of maternal immune system in early pregnancy with Concanavalin A, a T-cell mitogen, prior to formation of fetal immune system impairs development of the offspring’s spleen and thymus. Our findings demonstrate that short-term exposure of pregnant murine dams to Concanavalin A, leads to retardation of postnatal development of offspring’s spleen and reduction of lymphocytes count in thymus medulla and accelerated formation of thymic corpuscles.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):24-28
views
Topography of thymus humans in early fetal period of its development
Galeeva E.N., Zheleznov L.M.
Abstract
Сongenital malformations of the thymus, the interpretation of which is difficult when ultrasound study of the chest cavity in the early stages of prenatal ontogenesis often put the question of choosing one of the planes 3 standard directions. Compliance plane images structures, ultrasound and sectional slices is key for conducting work in this direction. The study was 60 human fetuses obtained at artificial abortion for social reasons in age from 16 to 18 weeks ’ gestation. New data have been obtained outside of organ topography of the thymus man in the early fetal period of ontogenesis, depending on the level and the slice of the torso of the fetus. Research data complement the information on the morphology of the thymus fetus and are basic in conducting ultrasound examination.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):29-34
views
Nicotinic acetylcholine receptors as modulators off sympathetic neurons and sattelit glial cells protein-synthesizing systems in cranial cervical ganglion
Gorelikov P.L.
Abstract
In the experimentally established pharmacological blockade of nicotinic cholinergic receptor type (nCR) was studied the dynamics of the content of RNA in the cytoplasm of neurons and in the sattelite glial cells cranial cervical sympathetic ganglion of rabbits. It was determined the neurotrophic nCR role in the cellular mechanisms of the ganglion, which lies in the fact that the synaptic signal through nHR has modulating effect on the activity of the protein-synthesizing system in neurons and is coordinating this activity with the metabolic activity of neighboring satellite glial cells.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):35-40
views
Autonomic "portrait" of different signs emotions subjective experience
Glazachev O.S., Dudnik E.N.
Abstract
Purpose - to identify the specificity in objective autonomic manifestations of different signs emotions of healthy persons in relation to subjective emotional phenomenology. When benchmarking subjective self-reports of experienced emotions and values autonomic in the process of laboratory simulation in 30 subjects negative and positive emotions found that the degree and sign of subjectively evaluated emotional experiences did not always correspond to characteristics of emotion-generating stimulus, and "autonomic portrait" did not associated with the severity and the "sign"of emotional subjective experiences. Students, subjectively experienced vividly expressed strong negative emotions, did not display adequate autonomic activation, but in modeling of positive emotions they retain the negative emotional background and prolonged sympathetic overactivation in cardiovascular functions. In subjects with dominance of positive subjective assessments of their emotional status in modeling of psychological stress and in relaxation minimum shifts to parasympathetic autonomic regulation were observed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):41-48
views
The state of the autonomous (vegetative) nervous system and heart rhythm disorders under exercise conditions
Pokhachevsky A.L., Lapkin M.M.
Abstract
Ingenious methods of exercise cardiac rhythmgram math simulation are used to study the autonomic regulation of the heart rate. Changes in a number of autonomic nervous system (ANS) - an increase in activity in general, and the manifestation of parasympathetic dominance reflects improved exercise tolerance. Supraventricular extrasystole, a typical heart beat disorder which is not observed at rest and manifesting under exercise conditions, is a consequence of its excess (overload) independently of the endurance development level. Improvement of adaptive mechanisms in the formation of endurance reduces the possibility of extrasystole due to the increase of a potentially dangerous load threshold, manifestation time and decrease in the number of extrasystole complexes. In turn, heart beat disorders have fundamental differences in the vegetative base depending on the endurance development level.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):49-56
views
LYMPHOPROLIFERATIVE DISEASES COMPLICATED BY OPPORTUNISTIC INFECTIONS
Bulieva N.B.
Abstract
Opportunistic infections often complicate the course of lymphoproliferative disorders. Study of changes of the immune status of patients with lymphoproliferative diseases complicated by opportunistic infection, it is an urgent problem.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):57-64
views
Oral hormonal contraceptive "janine" influence on P-glycoprotein functional activity
Yakusheva E.N., Kotlyarova A.A., Nikiforov A.A.
Abstract
In the research on rabbits influence of combined oral contraceptive, "Janine" on the functional activity of the protein efflux transporter P-glycoprotein (Pgp) was studied. Pgp activity was assessed by pharmacokinetic analysis of marker substrate fexofenadine. It was found that administration of the drug "Janine" for 14 and 21 days, resulting in inhibition of Pgp functional activity.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):65-70
views
Analysis of the russian wholesale market of eye drops for 2006 - 1-3 quarter 2012
Arustamova A.A., Pokrovsky M.V., Shabelnikova A.S., Kashuba A.S.
Abstract
This article contains analysis of the Russian wholesale market of eye drops for 2006 - 1-3 quarter 2012 using pharmacoeconomic and economic-mathematical methods of analysis. The objects of study were the wholesale market of eye drops registered in the Russian Federation, during the study time period, the official source of information - the Register of medicines in Russia (2012). The analysis for 2006 - 1-3 quarter 2012 found rising wholesale eye drops by a robust demand.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):71-76
views
Role of ATP-dependent K + channels in erythropoietin effects on abdominal organs volumetric blood flow velocity at ischemia/reperfusion
Pokrovsky M.V., Alehin S.A., Ivanova L.V., Nazarenko D.P., Kolmikov D.I.
Abstract
In this article erythropoietin influence on volumetric blood flow velocity in different abdominal organs at early ischemia/reperfusion stages were shown. We determine that glibenclamid as mitochondrial ATPdependent K+ channels blocker abolish erythropoietin protective effects, increasing transient hyperemia, at the same time pancreas has reaction different from other abdominal organs to ischemia/reperfusion and pharmacological agents intake.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):77-82
views
Monitoring of air quality in the city
Lyapkalo A.A., Dementiev A.A., Tsurgan A.M.
Abstract
In the article there is outcome analysis of air quality monitoring in Ryazan by the data of stationary sites. Daily and season dynamics of the average content of carbon oxide and nitrogen dioxide in the air in the warm and cold seasons are investigated and analyzed by the dispenser analysis. Periods characterized by the highest average concentrations of pollutants in the air are revealed. The relation between the air pollution level and the motor transport emissions is revealed and analyzed. Direct correlation dependence between air pollution by carbon oxide and nitrogen dioxide and the motor transport emissions in the cold season is detected.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):83-89
views
Anomalies of kidneys development among the children with idiopatic scoliosis of Ryazan region
Pankratova G.S.
Abstract
The aim: to study the anatomical and topographical peculiarities of urineflowing system organs among the children with idiopatic scoliosis. This work was based on the results of the kidneys ultrasound research carried out among 425 children with idiopatic scoliosis with Cobb ’s angle from 5 to 60 degrees. Children from 4 to 17 years old were under the research. It was shown that the anomalies of urineflowing system organs development exceed population indexes many times. Ultrasound research of kidneys should be included in the obligatory diagnostic investigation of children with idiopatic scoliosis.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):90-94
views
Endoscopic ultrasound role of research in the determination of the possibility endo-biliary stenting in patients with neoplastic lesions periampulyary zone
Chabounine A.V., Tavobilov M.M.
Abstract
The article presents the results of treatment of 249 patients with neoplastic lesions of the head of the pancreas complicated by obstructive jaundice secondary to severe , were treated at the surgical clinics GKB after SP Botkin Clinical Hospital № 1 and the NI Pirogov from 2008 to 2012. The ratio of male to female ratio was 1:1.7 , respectively (155 and 194). Mean age was 65,8 ± 0,7 years. It is shown that the use of the algorithm instrumental diagnosis in patients with obstructive jaundice , including EndoUZI allows a differentiated approach to the choice of biliary decompression in patients with obstructive jaundice of tumorous lesions of the pancreatic head.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):95-103
views
Value assessment in outflow tract reconstruction femoral-tibial
Pokrovsky A.V., Yahontov D.I.
Abstract
The paper presents an algorithm for estimating the initial state outflow tract and assessment of their impact on the immediate and long-term results of treatment of patients with obliterating diseases of the femoral- popliteal - tibial segment. The study included 92 patients who had undergone multiple reconstructive operations in the segment below the knee and, 15.2 % of the patients initially had good outflow tract , in 39.1 % of patients determined satisfactory condition outflow tract and in 45.7 % of cases initially identified poor outflow tract.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):104-112
views
Phenotypic markers of connective tissue dysplasia in primary spontaneous pneumothorax
Miheev A.V., Trushin S.N., Baskevich M.A.
Abstract
The paper presents the results of a survey of 21 patients with primary spontaneous pneumothorax using valuation techniques phenotypic criteria of connective tissue dysplasia.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):113-116
views
Prognostic significance of degree histologically malignant ductal pancreatic adenocarcinoma
Filippova E.M., Pakhlim O.V., Chekmareva I.A., Kochatkov A.V., Lebedeva A.N., Kravchenko E.V.
Abstract
The article presents the results of a study of 47 patients (22 males and 25 females) PAK prostate treated at Institute of Surgery. A.V. Vishnevsky from 2005 to 2012. The age of patients ranged from 47 to 76 years, mean age was 60 years. In 24 patients at the time of surgery was diagnosed IIb (pT2- 3, N1) tumor stage, 19 - IIa (pT2-3, N0), have 3 -III (pT4), from 1 - Ib (pT2, N0). In 27 observations revealed metastases to regional lymph nodes (N1). Staging was performed according to the revision of the International Classification of 7 TNM (UICC, 2010). The results also show that such clinical and morphological characteristics as gender, patient age, stage and tumor size did not affect the postoperative survival. No significant correlation between patient survival and tumor grade (grade), determined by the degree of differentiation, as recommended by WHO. In contrast, when using the Gleason system, which takes into account not only the most abundant component in the tumor, but also the second most common, obtained a significant correlation with postoperative survival rates, making this a promising grading system for use in the diagnosis of ductal adenocarcinoma of the pancreas.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):117-127
views
Research flow cytometric of the DNA content in tumor cells of lung cancer patients with paraneoplastic rheumatic syndrome
Lysenko S.A., Kirkilevsky S.I., Chereshnyuk I.L.
Abstract
The study of the DNA content and cell cycle indicators of tumor cells of 70 lung cancer patients: 30 patients with paraneoplastic rheumatic syndrome (PNRS) and 40 - without manifestations of the syndrome. Found that in tumors of lung cancer patients with PNRS, unlike tumors of lung cancer patients without symptoms of this syndrome are observed higher proliferative activity of tumor cells (S-phase), increased indicators of DNA aneuploidy (DNA index, cell index, aneuploidy index) and also have lower levels of apoptosis. All these changes are indicative of more highly aggressiveness and malignancy of tumor process in lung cancer patients with PNRS.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):128-133
views
Morphologic and morphometric description of vascular component part (vessels of microcirculatory net and cell population around them) of communication systems in the cervical carcinona tissues
Bekhtereva I.A.
Abstract
The data of morphometric and morphologic study of cervical carcinoma is cited in this article. Morphometric study of cellular population revealed significant increase of fibroblasts, lymphocytes, plasmocytes and macrophages around arteriola, capillaries, venula in the tumour's tissues in comparison with contralateral region. The number of lymphocytes, plasmocytes and granulocytic leucocytes around venula and capillaries in the tumour's region was growing as compared with contralateral region. Fibrocytes' and macrophages' population and parenchymal cells were the most stable.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):134-138
views
Matrix metalloproteinase-9 as a biomarker of poag
Sokolov V.A., Levanova O.N., Nikiforov A.A.
Abstract
Diagnosis of primary open angle glaucoma (POAG) early stages of the pathological process remains a difficult task, even for experienced ophthalmologists. This work is devoted to the study of matrix metalloproteinase-9 (MMP-9) in lacrimal fluid of patients with POAG as a biomarker of this disease. Revealed a significantly higher concentration of MMP-9 in a lacrimal fluid in patients with glaucoma, at the initial stage of the pathological process. Dependence between levels of MMP-9 and stages of the pathological process has been established.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):139-142
views
Kinds of rhinolordosis at the combined deformations of a nose and methods of their surgical correction
Medvedev V.A.
Abstract
In the group consisted of 56 patients with rhinolordosis, combined with other deformities of the nose was the most often identified (total) bone and cartilage form of rhinolordosis - 31 cases (the sizes of implants were the largest and donor cartilage was commonly used). Cartilaginous form was less commonly observed - 22 observations (the sizes of implants were smaller and donor cartilage was used less frequently). The most rare form of rhinolordosis was bone kind - 3 cases (the sizes of implants were the smallest and only autocartilage of the nasal septum was used). The use of a donor cartilage at lack of an own material during operations concerning rhinolordosis is justified and expediently.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):143-147
views
Regularities of gastrointestinal sphincter structure and functions
Lazutina G.S., Rumyantseva T.A.
Abstract
The article provides a brief literature review of the definitions "sphincters of digestive system.” The authors discuss various morphological data of gastrointestinal sphincters in connection of structure, function and organization of their innervation. The article presents data of different authors about terminology, classifications and innervation of the sphincter apparatus of the gastro-intestinal tract. Particular attention is paid to the role of their own pacemaker interstitial cells of Cajal (the organizers of peristalsis).
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):148-153
views
The functional mechanisms of the white line of the abdomen and their role in the pathogenesis of ventral hernia
Fedoseyev A.V., Muravev S.J., Avdeev S.S., Gazuani A.I.
Abstract
The article gives a detailed analysis of the scientific work and their own data for the last ten years devoted to the problem of treatment of patients with umbilical hernias. Covered in detail and summarized the practical experience of various authors on the surgical treatment of patients with this pathology. Identified the causes of relapse and development periomphalic umbilical hernia in the postoperative period . Based on a detailed analysis of morfofuntional and biomechanical properties of the fascial- musculo- aponeurotic complex abdominal wall author justifies the use of prosthetic techniques in closing the defect of the umbilical ring.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):154-161
views
Principles of modern treatment of multiple sclerosis (at the example of Ryazan region)
Lorim L.V., Dzhaparalieva N.T., Mikheeva L.M.
Abstract
Treatment of multiple sclerosis (MS) is one of the most challenging problems of the modern practice of neurology. Due to the fact that the etiology of the disease is still un-clear,and it is impossible for prevention and etiological therapy. At the same time, the active introduction of drugs in the clinical practice of disease-modifying therapy for multiple sclerosis (DMT), earlier was kind of impossible but at present days it is one the of the difficult disease to treat. Now a days, immunomodulatory drugs are the drug of choice for thepathogenetic treatment of MS. The paper presents the main factors determining the current approaches to the treatment of MS. Based on the literature data and the results of our observations are given basic regimen in different stages of the disease depending on the type of disease in MS patients at Ryazan region.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):162-167
views
The memory of professor A.F. Belov
- -.
Abstract
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):168-169
views
K SVEDENIYu AVTOROV
- -.
Abstract
I.P. Pavlov Russian Medical Biological Herald. 2013;21(4):171-174
views

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies