Correlation of Immunogenicity the different oat varieties from children with celiac disease and expansion gluten-free diet


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Most of the recent studies suggest that oats are well tolerated by celiac disease patients. However, it is still possible that different oat cultivars may display different biological properties relevant for celiac disease pathogenesis. The aim of this study was to investigate biological and immunological properties of two oat varieties, in relation to their safety for CD patients. Our data show different immunological properties of two oat varieties for celiac disease patients. It is necessary update on serologic testing for anti-avenin antibodies for individualization gluten-free diet.

Full Text

Restricted Access

About the authors

Natalya Vasilyevna Vokhmyanina

St. Petersburg State medical establishment «Diagnostic Medical Genetic Center»

Email: spbnat@yandex.ru
PhD, Сhief of Laboratory

Inna Pavlovna Gavrilyuk

St. Petersburg Academy of Agricultural Sciences

Email: saidakubalova@mail.ru
MD, PhD, Professor, Department of Cereals

References

  1. Di Sabatino A., Corazza G. Coeliac disease // Lancet. — 2009. — Vol. 373. — P. 1480–1493.
  2. Dickey W. Making oats safer for patients with coeliac diseas // Eur. J. Gastroenterol Hepatol. — 2008. — Vol. 20. — P. 494–495.
  3. Guttormsen V., Løvik A. et al. No induction of anti-avenin IgA by oats in adult, diet-treated coeliac disease // Scand. J. Gastroenterol. — 2008. — Vol. 43 (2). — P. 161–165.
  4. Haboubi N., Taylor N., Jones S. Coeliac disease and oats: a systematic review // Postgrad. Med. J. — 2006 October. — Vol. 82 (972). — P. 672–678.
  5. Jonas F. Ludvigsson and Alessio Fasano Timing of Introduction of Gluten and Celiac Disease Risk // Ann. Nutr. Metab. — 2012. — Vol. 60 (suppl 2). — P. 22–29.
  6. Koning F. Toxicity of prolamins in celiac disease // International Celiac Disease Meeting, Maribor, 13–16 September. — 2007. — P. 49–54.
  7. Kumar V., Wijmenga C., Withoff S. From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases // Semin. Immunopathol. — 2012. — Vol. 34. — P. 567–580.
  8. Lionetti E., Catassi C. New Clues in Celiac Disease, Epidemiology, Pathogenesis, Clinical Manifestations, and Treatment // International Reviews of Immunology. — 2011. — Vol. 30. — P. 219–231.
  9. Mazzarella G., Barone M., Gianfrani C. et al. Immunogenicity of two oat varieties, in relation to their safety for celiac patients // Scand. J. Gastroenterol. — 2011, Aug 15. [Epub ahead of print].
  10. Trynka G., Wijmenga C., A van Heel D. A genetic perspective on coeliac disease Trends // Mol. Med. — 2010. — Vol. 16 (11). — p. 537–550.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2013 Vokhmyanina N.V., Gavrilyuk I.P.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 69634 от 15.03.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies