Molecular genetics — a way to the individual personalized medicine

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Review of modern technologies that are used for identification and mapping of genetic risk factors associated with different multifactorial diseases. The principles of the wide genomic association scan (GWAS) are accounted. A significance of this method is considered on the example of hereditary predisposition to autoimmune diseases. The role of MCH complex gene polymorphism and specific genetic risk factors in the autoimmunity forming and a possibility of multifactorial diseases personalized therapy with taking into account of the patient hereditary constitution are discussed.

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About the authors

Viktoriya Nikolayevna Gorbunova

Saint-Petersburg State Pediatric Medical University

MD, Professor, Deptartment of medical genetics


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Copyright (c) 2013 Gorbunova V.N.

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