Differential evaluation of iron metabolism in children with hypochromic anemia

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Abstract


In the article are presented the indicators of iron metabolism in the two groups of children with hypochromic anemia in age from 7 months to 16 years who were examined in the Consultative and Diagnostic Center for Children of St. Petersburg: 28 patients with iron deficiency anemia and 21 patients with thalassemia minor. Characteristic changes are marked at children with IDA: reduced average iron and ferritin of serum and increasing the total iron binding capacity (TIBC) and soluble transferrin receptor (RTR). Children with thalassemia minor are characterized normal average serum iron, TIBC and ferritin, and a slight increase in RTR. But when we’ve analyzed the vibrations of each of these parameters in different groups of children, we founded a more diverse spectrum of disorders that may be associated with a combination thalassemia minor and iron deficiency, as well as the presence of comorbidities and conducted recently therapy by ferrum. Conclusion: it is necessary to evaluate the maximum number of biochemical parameters of iron metabolism, taking into account premorbid background and comorbidity.

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About the authors

Ksenia I Pshenichnaya

Saint Petersburg State Pediatric Medical University of Health Ministry of Russia

Email: kpshenichnaya@yandex.ru
MD, PhD, Dr Med Sci, Professor, Department of Pediatrics, Endocrinology and Abilitologii AF and DPO. St. Petersburg State Pediatric Medical University.

Yuliya I Zhilenkova

North-Western State Medical University named after I.I. Mechnikov

Email: yuliaismailovna@mail.ru
Postgraduate Student. ClinicalChemistry Department. I. I. Mechnikov Northwestern State Medical University.

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