Immunohistochemical value to treat patients with chronic endometritis

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Abstract

One of the main causes of violations of women’s fertility is the pathology of the endometrium. Structural and functional inferiority of endometrium due to pathological inflammation, naturally leads to disruption of the implantation process and clinically infertility and prenatal losses. Finding solutions treatment of endometrial pathology exclusively relevant for the prevention of reproductive health of society. The main causes of diseases of the endometrium is inadequate hormonal regulation, acute and chronic inflammation (endometritis). Consistently high frequency CE denies membership issues to the category of banal, more kontraversii recent years postulate avoiding one-sided perception of the disease solely as a classic suppurative inflammation. For chronic endometritis is often characterized by a long asymptomatic and complexity of initial diagnosis. Important role in the development of chronic endometritis today belongs to obligate anaerobes - Bacteroides and peptostreptokokki, combined with microaerophiles and facultative anaerobic microorganisms. A special place in the development of chronic endometritis takes herpes infection. Its prevalence in all, including reproductive age is quite high. Special attention is paid to the verification of chronic endometritis immunohisto-chemical (IHC) study of the endometrium. The method can not only identify the type of infectious agent, but also to establish phase process, which has an important role to determine the treatment strategy. A special role is played by immunohistochemistry in the identification of viral etiology of chronic endometritis, as this method can reliably detect the presence of antigens to a variety of viral agents.

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About the authors

Vera A Kolmyk

St Petersburg State Pediatric Medical University Ministry of Health of the Russian Federation

Author for correspondence.
Email: vera-kolmyk@mail.ru
Postgraduate Student. Department of Children Gynecology and Female Reproductology, Faculty of Postgraduate Education Russian Federation

Ruslan A Nasyrov

St Petersburg State Pediatric Medical University Ministry of Health of the Russian Federation

Email: rrmd99@mail.ru
MD, PhD, Dr Med Sci, Professor, Head. Department of Pathological Anatomy at the rate of Forensic Medicine Russian Federation

Galiya F Kutusheva

St Petersburg State Pediatric Medical University Ministry of Health of the Russian Federation

Email: Galiya@chadogyn.ru
MD, PhD, Dr Med Sci, Professor, Head. Department of Children Gynecology and Female Reproductology, Faculty of Postgraduate Education Russian Federation

Vitaliy V Petrov

Military Medical Academy named after S.M. Kirov

Email: petrovit@inbox.ru
MD, PhD, Resident doctor. Department of Military Surgery Russian Federation

Stepan G Grigoryev

Military Medical Academy named after S.M. Kirov

Email: Gsg_rj@mail.ru
MD, PhD, Dr Med Sci, Leading Scientist. Department of Medical Service Management Automation Russian Federation

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Copyright (c) 2016 Kolmyk V.A., Nasyrov R.A., Kutusheva G.F., Petrov V.V., Grigoryev S.G.

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