Diagnostics and prevention of infections caused by Streptococcus agalactiae in pregnant women and newborn infants


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Abstract

The study investigates colonization of the genitourinary tract and rectum in pregnant women by Streptococcus agalactiae in early pregnancy, as well as pregnancy outcomes for mother and infant depending on the use of antibiotic prophylaxis. The frequency of GBS colonization was 15.9 %, with the detection rate in urine being 8.6 %, in the vagina - 3.5 %, in the rectum - 10 %. The efficiency of amoxicillin/clavulanic acid administered in the II trimester was 66.7 %. Pregnancy outcomes in women receiving and those not receiving antibiotic prophylaxis were studied. In all women receiving amoxicillin/clavulanic acid term labor occurred, with healthy full-term infants born. In one woman not receiving antibiotic prophylaxis there was preterm labor at 34 weeks of gestation.

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About the authors

Svetlana L’vovna Zatsiorskaya

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: zatziorskaya@yandex.ru
PhD, Senior Researcher, Laboratory of Microbiology

Anna Alexandrovna Krysanova

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: annakr@inbox.ru
Researcher, Laboratory of Microbiology

Vladislav Olegovich Khvan

Saint Petersburg state Maternity hospital N 18

Email: vladvit2001@inbox.ru
Obstetrician-gynecologist

Zinaida Mikhailovna Martikainen

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: zinaida.martikaynen@gmail.com
PhD, Senior Researcher, Laboratory of Microbiology

Alevtina Mikhailovna Savicheva

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: savitcheva@mail.ru
MD, PhD, Dr Med Sci, Professor, Laboratory of Microbiology

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Copyright (c) 2014 Zatsiorskaya S.L., Krysanova A.A., Khvan V.O., Martikainen Z.M., Savicheva A.M.

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