Diagnostics and prevention of infections caused by Streptococcus agalactiae in pregnant women and newborn infants

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract


The study investigates colonization of the genitourinary tract and rectum in pregnant women by Streptococcus agalactiae in early pregnancy, as well as pregnancy outcomes for mother and infant depending on the use of antibiotic prophylaxis. The frequency of GBS colonization was 15.9 %, with the detection rate in urine being 8.6 %, in the vagina - 3.5 %, in the rectum - 10 %. The efficiency of amoxicillin/clavulanic acid administered in the II trimester was 66.7 %. Pregnancy outcomes in women receiving and those not receiving antibiotic prophylaxis were studied. In all women receiving amoxicillin/clavulanic acid term labor occurred, with healthy full-term infants born. In one woman not receiving antibiotic prophylaxis there was preterm labor at 34 weeks of gestation.

Full Text

Restricted Access

About the authors

Svetlana L’vovna Zatsiorskaya

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: zatziorskaya@yandex.ru
PhD, Senior Researcher, Laboratory of Microbiology

Anna Alexandrovna Krysanova

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: annakr@inbox.ru
Researcher, Laboratory of Microbiology

Vladislav Olegovich Khvan

Saint Petersburg state Maternity hospital N 18

Email: vladvit2001@inbox.ru
Obstetrician-gynecologist

Zinaida Mikhailovna Martikainen

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: zinaida.martikaynen@gmail.com
PhD, Senior Researcher, Laboratory of Microbiology

Alevtina Mikhailovna Savicheva

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: savitcheva@mail.ru
MD, PhD, Dr Med Sci, Professor, Laboratory of Microbiology

References

  1. Башмакова М. А., Кошелева Н. Г., Калашникова Е. П. Инфекция и бактериальная колонизация урогениталий у беременных, влияние на течение беременности, плод и новорожденного // Акуш. и гинек. - 1995. - № 1. - С. 18.
  2. Зациорская С. Л. Стрептококки группы B у беременных женщин и новорожденных: Автореф. дисс… канд. мед. наук. - СПб., 1996.
  3. Оганян К. А., Зациорская С. Л., Аржанова О. Н., Савичева А. М. Колонизация мочевых путей беременных стрептококками группы В и перинатальные исходы // Журнал акушерства и женских болезней. - 2006. -Т. LV, вып. 1. - С. 26-31.
  4. Оганян К. А. Течение и исход беременности при колонизации мочеполового тракта женщин стрептококками группы B и D: Автореферат дис… канд. мед. наук. - СПб, 2008.
  5. Тотолян А. А., Суворов А. Н., Дмитриев А. В. Стрептококки группы B в патологии человека. - СПб.: Человек, 2009. - С. 211.
  6. American Academy of Pediatrics. Revised guidelines for prevention of early-onset group B streptococcal (GBS) infection. American Academy of Pediatrics Committee on Infectious Diseases and Committee on Fetus and Newborn // Pediatrics. - 1997. - Vol. 99. - P. 489-496.
  7. Baker S., Edwards M. S. Group B streptococcal infections // Infections Deseases of the Fetus and Newborn Infant, 4th ed. / Remington J. S. And Klein O. J. (eds.). - Philadelphia, The W. B. Saunders Co., 1995. - P. 980-1054
  8. Baltimore R. S. Consequences of prophylaxis for group B streptococcal infections of the neonate // Semin. Perinatol. 2007. - Vol. 31, N 1. - P. 33-38.
  9. Bolter S., Whitney C., Schuchat A. Epidemiology of group B streptococcal infections // Gram-Positive Pathogens / Fishetti et al. (eds.). - Washington D. C.: American Society for Microbiology, 2000. - P. 154-162.
  10. CDC. Prevention of perinatal group B streptococcal disease: revised guidelines from CDC. - MMWR 2002. - 51 (No. RR - 11).
  11. Whitney C. G., Plikaytis B. D., Gozansky W. S. et al. Prevention practices for perinatal group B streptococcal diseases: multistate surveillance analysis // Obstet. Gynecol. - 1996. - Vol. 89. - P. 28-32.
  12. Yancey M. K., Duff P., Kubilis P. et al. Risk factors for neonatal sepsis // Obstet. Gynecol. - 1996. - Vol. 87. - P. 188-194.

Statistics

Views

Abstract - 616

PDF (Russian) - 715

Cited-By


Article Metrics

Metrics Loading ...

PlumX

Dimensions


Copyright (c) 2014 Zatsiorskaya S.L., Krysanova A.A., Khvan V.O., Martikainen Z.M., Savicheva A.M.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies