Functional endotelian condition of woman with metabolic syndrome associated with autoimmune thyroiditis

The purpose of the research was a complex clinical-instrumental examination of structural and functional artery condition of patients with metabolic syndrome, autoimmune thyroiditis -euthyreose and subclinical hypotheriosis at the background of substitution therapy. Three groups were made during the research: 1 group (23 women) with metabolic syndrome without pathology of thyroid gland, 2 group (14 people) with autoimmune thyroiditis - euthyreose, 3 group (14 woman) with subclinical hypotheriosis. The instrumental examination included assessment of endothelial function and artery hardness, intima-media complex by ultrasound method. The results showed that first two groups of patients ware characterized by the increase of artery hardness with endothelium dysfunction, having normal indices of endothelium-independent vasodilatation (EIVD). The prescription of substitution therapy led to the improvement of the indices of EDVD and to the decrease of the progressing of vascular hardness.

autoimmune thyroiditis, subclinical hypotheriosis, endothelial, dysfunction, artery hardness, substitution therapy