Functional dyspepsia through chronic gastritis in patients with marfan syndrome and marfan-like states
- 作者: Rudoy A.S1, Uryvaev A.M1
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隶属关系:
- Educational Institution “Belarusian State Medical University”
- 期: 卷 7, 编号 3 (2016)
- 页面: 76-83
- 栏目: Articles
- URL: https://journals.eco-vector.com/pediatr/article/view/5727
- DOI: https://doi.org/10.17816/PED7376-83
- ID: 5727
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详细
The article presents the results of clinical and endoscopic examination of patients (n = 89; 33 ± 9,3 years; F : M/23 : 66) with confirmed chronic gastritis associated with hereditary disorders of connective tissue (Marfan syndrome phenotype and Marfan-like states) in order to examine the relationship associated HDCT as monogenic diseases - Marfan syndrome, as well as related pathology in the form of Marfan-like states with the clinical manifestations of functional dyspepsia and endoscopic picture of H. pylori infection in chronic gastritis. Diagnosis of Marfan syndrome was based on the revised criteria of Ghent. For the differential diagnosis with other “related” diseases of the connective tissue used syndrome diagnostic criteria of hypermobility of joints, Ehlers - Danlos syndrome. Evaluation of complaints and diagnosis of functional dyspepsia was based on the criteria of Rome III (2006) and the Florence Agreement. Evaluation of the symptoms of functional dyspepsia showed different from control (p < 0,05) lower frequency of epigastric pain syndromes and postprandial distress syndrome in a group with Marfan syndrome not associated with H. pylori infection and, at the same time, does not correlate with available in this group of patients a high frequency of precancerous lesions in the gastric mucosa. Frequent endoscopic manifestations associated with the HDCT served esophagitis gastroduodenal motility disorders and the development of GERD with catarrhal esophagitis (p < 0,05) and the absence of erosive and ulcerative lesions of gastroduodenal mucosa (p < 0,05). The findings strongly indicate the absolute necessity of endoscopic and morphological screening regardless of the presence of gastrointestinal complaints in patients with associated HDCT.
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作者简介
Andrey Rudoy
Educational Institution “Belarusian State Medical University”
编辑信件的主要联系方式.
Email: andrewrudoj@gmail.com
MD, PhD, Dr Med Sci. Department of Military Field Therapy 俄罗斯联邦
Alexey Uryvaev
Educational Institution “Belarusian State Medical University”
Email: alexeyuryvaev@gmail.com
Assistant Professor. Department of Military Field Therapy 俄罗斯联邦
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