The influence of vital stress experienced by women in pregravidarum period on sexual development of their daughters

Comparative evaluation of sexual development among adolescent girls whose mothers experienced and did not experience psychological trauma associated with life-threatening was conducted. The physiological features of sexual development in girls in the Republic of Dagestan, whose mothers experienced a high risk of terror threat in pregravidarum period were identified. It was determined that in pre-pubertal period the concentration of luteinizing and follicle-stimulating hormone in peripheral blood in girls whose mothers experienced stress associated with life-threatening was significantly higher than in girls of the control group. In prepubertal period in girls whose mothers experienced a vital stress, the earlier decrease in the activity of the adrenal cortex in the transition from prepuberty to puberty was observed. Girls whose mothers experienced a vital stress can be characterized by an earlier menarche, at the age of 10-12 the menarche occurred significantly more often than in the control group. The anthropometric data show an earlier maturation of these girls under the age of 12. In the prepubertal period the formation of breast and pubic hair growth were ahead of girls in the control group. Thus, girls whose mothers experienced vital stress are characterized by an earlier and at the same time disharmonious puberty. They are characterized by earlier menarche, delayed rhythm of the menstrual cycle and some changes in humoral regulation rhythm. Thus, it is vital the stress suffered by women before pregnancy causes changes in hormonal regulation in pregnancy that leads to long-term damage of physiological homeostasis of the offspring.