The effectiveness of different regimens of testosterone gel therapy in men with androgen deficiency

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The results of androgen replacement therapy with the appointment of a transdermal gel with testosterone in patients with androgen deficiency were presented. 90 men with testosterone deficiency (<12 nmol/L) and impaired erectile function were observed. The average age of patients was 58 ± 5.2 years. Patients were divided into 3 groups. Patients of the 1st (control) group underwent basic behavioral therapy, the 2nd group received basic therapy with testosterone gel for a dose of 50 mg, the 3rd group received basic therapy with testosterone gel at a dose of 100 mg. The duration of treatment was 6 months. The use of testosterone in the form of a transdermal gel led to a significant increase in the content of total testosterone in both patients of the 2nd (50 mg) and 3rd groups (100 mg). A dose-dependent effect was noted, in patients of the 3rd group the level of testosterone was significantly higher than in patients 2nd group. An increase in testosterone was accompanied by a decrease in FSH and LH levels.

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作者简介

Andrey Kuzmenko

N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation

编辑信件的主要联系方式.
Email: kuzmenkoav09@yandex.ru

Doctor of Medical Science, Professor, Head, Department of Urology

俄罗斯联邦, Voronezh

Timur Gyaurgiev

N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation

Email: tima001100@mail.ru

Candidate of Medical Science, Associate Professor, Department of Urology

俄罗斯联邦, Voronezh

Yulia Bakutina

N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation

Email: yul.bakutina@yandex.ru

Student

俄罗斯联邦, Voronezh

Alena Zarubayco

N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation

Email: alenazarubaiko@yandex.ru

Student

俄罗斯联邦, Voronezh

参考

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版权所有 © Kuzmenko A.V., Gyaurgiev T.A., Bakutina Y.Y., Zarubayco A.Y., 2020

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