Polymorphisms of the BDNF (rs6265) and LIPC (rs2043085) genes associated with the violation of military professional activity in the Arctic zone

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Abstract

The association of polymorphisms of 8 different genes with the pathology of the nervous and cardiovascular systems of military personnel serving in the Arctic zone was studied. It has been shown that military personnel with the G/G genotype (G/A polymorphism – rs6265 in the brain-derived neurotrophic factor BDNF gene) in combination with the C/C genotype (T/C polymorphism – rs2043085 of the LIPC gene) are recommended for service in the Arctic belt. Ceteris paribus, it is preferable that the genotype of officers serving in the Arctic zone be G/G for the BDNF gene and C/C for the LIPC gene (rs6265 and rs2043085 polymorphisms, respectively). From a prognostic point of view, the selection criteria for military personnel by genotypes will increase the combat capabilities of groupings of troops (forces) in the Arctic zone of Russia.

About the authors

A. V. Lemeshchenko

The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation

Author for correspondence.
Email: lav_1981@mail.ru

кандидат медицинских наук, подполковник медицинской службы

Russian Federation, Saint Petersburg

V. N. Tsygan

The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation

Email: lav_1981@mail.ru

заслуженный деятель науки РФ, профессор, полковник медицинской службы в отставке

Russian Federation, Saint Petersburg

E. A. Kazakova

The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation

Email: lav_1981@mail.ru

кандидат биологических наук

Russian Federation, Saint Petersburg

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Copyright (c) 2023 Lemeshchenko A.V., Tsygan V.N., Kazakova E.A.


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: № 01975 от 30.12.1992.

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