Comparison of the effectiveness of extracorporeal detoxification methods in the treatment of post-load rhabdomyolysis complicated by acute renal damage
- Authors: Belskikh A.N1, Zakharov M.V1, Marukhov A.V1, Korolkov O.A1
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Affiliations:
- FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
- Issue: Vol 340, No 6 (2019)
- Pages: 49-54
- Section: Articles
- URL: https://journals.eco-vector.com/0026-9050/article/view/81896
- DOI: https://doi.org/10.17816/RMMJ81896
- ID: 81896
Cite item
Abstract
To study the effectiveness of different methods of renal replacement therapy for treatment of afterload rhabdomyolysis was considered a case of treating a patient of 21 years with postload rhabdomyolysis complicated by acute renal damage. The patient was counted and compared the values of clearance and elimination (relative clearance) of myoglobin during different variants of renal replacement therapy: hemofiltration in predilution and postdilution modes, as well as hemodiafiltration in predilution and postdilution modes. The highest values of clearance and elimination of myoglobin (69.2 ml/min and 23.1%, respectively) were obtained during hemodiafiltration in the post-dilution mode, which made it possible to level the damaging potential of myoglobin and contributed to the complete restoration of renal function.
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About the authors
A. N Belskikh
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian FederationSaint-Petersburg
M. V Zakharov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
Email: zamivlad@yandex.ru
Saint-Petersburg
A. V Marukhov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
Email: maruxov84@mail.ru
Saint-Petersburg
O. A Korolkov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian FederationSaint-Petersburg
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