Comparison of the effectiveness of extracorporeal detoxification methods in the treatment of post-load rhabdomyolysis complicated by acute renal damage
- Authors: Belskikh A.N1, Zakharov M.V1, Marukhov A.V1, Korolkov O.A1
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Affiliations:
- FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
- Issue: Vol 340, No 6 (2019)
- Pages: 49-54
- Section: Articles
- URL: https://journals.eco-vector.com/0026-9050/article/view/81896
- DOI: https://doi.org/10.17816/RMMJ81896
- ID: 81896
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Abstract
To study the effectiveness of different methods of renal replacement therapy for treatment of afterload rhabdomyolysis was considered a case of treating a patient of 21 years with postload rhabdomyolysis complicated by acute renal damage. The patient was counted and compared the values of clearance and elimination (relative clearance) of myoglobin during different variants of renal replacement therapy: hemofiltration in predilution and postdilution modes, as well as hemodiafiltration in predilution and postdilution modes. The highest values of clearance and elimination of myoglobin (69.2 ml/min and 23.1%, respectively) were obtained during hemodiafiltration in the post-dilution mode, which made it possible to level the damaging potential of myoglobin and contributed to the complete restoration of renal function.
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About the authors
A. N Belskikh
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian FederationSaint-Petersburg
M. V Zakharov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
Email: zamivlad@yandex.ru
Saint-Petersburg
A. V Marukhov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian Federation
Email: maruxov84@mail.ru
Saint-Petersburg
O. A Korolkov
FGBOU VPO "Military medical Academy named after S. M. Kirov" MO of the Russian FederationSaint-Petersburg
References
- Жарский С.Л., Слободянюк О.Н., Слободянюк С.Н. Рабдомиолиз, связанный с физической нагрузкой у лиц молодого возраста // Клин. мед. - 2013. - № 3. - С. 62-65.
- Слободянюк С.Н. Рабдомиолиз вследствие физической нагрузкиу мужчин молодого возраста в организованном коллективе: Автореф. дис.. канд. мед. наук. - Хабаровск, ГБОУ ВПО ДГМУ, 2013. - 24 с.
- Хорошилов С.Е., Никулин А.В. Патогенез, диагностика и эфферентное лечение рабдомиолиза, осложненного острой почечной недостаточности // Тверской мед. журн. - 2017. - № 5. - С. 10-15.
- Albert C., Haase M., Bellomo R., Mertens P.R. High cut-off andhigh-flux membrane haemodialysis in a patient with rhabdomyolysis-associated acute kidney injury // Crit. Care Resusc. - 2012. - Vol. 14 (2). - Р. 159-162.
- Core Concepts in Dialysis and Continuous Therapies / Colm C., Magee J., Kevin Tucker, Ajay K. Singh (Editors). - Springer, 2016. - 292 p.
- Naka T., Jones D., Baldwin I., Fealy N., Bates S., Goehl H. et al. Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report // Crit. Care. - 2005. - Vol. 9 (2). - Р. 90-95.
- Petejova N., Martinek A. Acute kidney injury due to rhabdomyolysis and renal replacement therapy: a critical review // Crit. Care. - 2014. - Vol. 18 (3). - Р. 224.
- Premru V., Kovac J., Ponikvar R. Use of myoglobin as a marker and predictor in myoglobinuric acute kidney injury // Ther. Apher. Dial. -2013. - Vol. 17. - Р. 391-395.
- Schwartz J., Winters L.J., Padmanabhan A., Balogun R.A., Delaney M., Linenberger M.L. et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice - Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Sixth Special Issue // Journal of Clinical Apheresis. - 2013. - Vol. 28. - Р. 145-284.
- Zimmerman J.L., Shen M.C. Rhabdomyolysis // Chest. - 2013. - Vol. 144. - Р. 1058-1065.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).