The Fruit Fly for Searching for Genes and Mechanisms that Control Cytoskeleton Structure
- Authors: Simonova O.B1
-
Affiliations:
- Koltsov Institute of Developmental Biology, RAS
- Issue: No 7 (2022)
- Pages: 40-46
- Section: Articles
- URL: https://journals.eco-vector.com/0032-874X/article/view/631038
- DOI: https://doi.org/10.7868/S0032874X22070079
- ID: 631038
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Abstract
Studies of regulatory factors and biochemical properties of the actin cytoskeleton are being successfully carried out in vitro on models or using cell cultures. However, the function of such factors in vivo, when they participate in development of incredible variety of cytoskeleton structure of the organism, remains not clear. To fully understand forms and functions of cytoskeleton structures, it is necessary, firstly, to compose a complete list of factors that regulate the assembly of structures, secondly, to determine the spatiotemporal mechanism which coordinates the activity of these factors, and thirdly, to specify the influence of these regulator factors and subordinated structures on the dynamics of development. This review considers innovative techniques that have made the fruit fly a powerful tool in the study of these issues.
Keywords
About the authors
O. B Simonova
Koltsov Institute of Developmental Biology, RAS
Email: osimonova@hotmail.com
Moscow, Russia
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