Vol 26, No 2 (2015)

Chronic obstructive pulmonary disease is presently considered as a disease of the airways and lung with systemic manifestations. The latter include cardiovascular events, particularly hypertension that may be caused by hypoxemia, systemic inflammation, systemic oxidative stress, and neurohumoral activation.

This study enrolled 149 patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), who were ascertained to have a high incidence of multifocal atherosclerosis. The poor predictors were found to include increased cardiac-ankle vascular index and statin therapy discontinuation after NSTE-ACS. The women are more frequently discharged from hospital with a diagnosis of unstable angina pectoris and have no atherosclerotic lesion in the coronary and peripheral arteries while the men more commonly develop non-Q-wave myocardial infarction and have multifocal injury in the vascular bed.

Sore throat caused by tonsillopharyngitis in the vast majority of cases is a very frequent reason people visit their doctor. Symptomatic therapy aimed mainly at relieving pain plays a large role in the treatment of tonsillopharyngitis. The local nonsteroidal ant-inflammatory drug flurbiprofen has the high efficacy and safety established in evidence-based clinical trials.

The capabilities of intraperitoneal chemotherapy have recently attracted increasing attention. The use of subcutaneous port systems for intraperitoneal administration of chemicals is effective both in combination therapy for gastric malignancies and as a palliative treatment method for patients with unresectable gastric cancer. The authors describe their own experience with fully implantable subcutaneous peritoneal Port-A-Cath systems for combined chemotherapy of disseminated gastric cancer. The installation and operating maintenance of the system are detailed; possible complications during its operation and methods for their prevention are given; and long-term treatment results are assessed.

Trends in neurological syndromes and transcranial Doppler ultrasound changes are estimated in patients with spondylogenic vertebrobasilar insufficiency during treatment.

Interstitial lung disease (ILD) is one of the common systemic manifestations of rheumatoid arthritis. High-resolution computed tomography can reveal the signs of ILD in 70% of cases.

Combination treatment using tacrolimus produced a pronounced clinical effect in a 60-year-old patient with the manifestations of discoid lupus erythematous on the scalp and keratoma at the nasal tip.

The authors show the high informative value of a lipocalin investigation in predicting the risk of acute kidney injury in acute pancreatitis and the absolute value of the HGAL test in verifying acute kidney injury, including that during urgent surgery.

The introduction of the hyaluronic acid is still considered as a qualitative breakthrough in the treatment of patients with osteoarthritis (OA). In order to obtain primary information to assess the market potential of hyaluronan in Russia in 20 centers in 18 cities conducted in-depth interviews with medical professionals as well as patients with OA. The data reveal a large potential market hyaluronic acid in Russia, which manifests itself as a high level of training, and a good response in patients with OA treatment. Proven efficacy and safety· as well as the diversity of the positive ef-fect is the basis for the widespread use of these drugs in OA for intraarticular injection as Suplazin and Suplazin 1-SHOT (Вioniche teoranta Co., Ireland).

A total of 373 neonatal infants on mechanical ventilation were examined. Microaspiration of gastric contents was established from the pepsin isolated from a tracheobronchial aspirate (TBA). In the children with microaspiration, the incidence and severity of bronchopulmonary dysplasia (BPD) in all degrees of gestational maturity were found to be higher and to increase in proportion to enhanced TBA pepsin activity and a shorter gestational period. In this patient category, a classic form of BPD prevailed in preterm infants, BPD was significantly more common than in the comparison group, and a follow-up study revealed a statistically significant number of cases of chronic bronchopulmonary disease developed by 3 years of life.

The result of treatment is increased if systemic etiological and pathogenetic therapy is prescribed, which becomes possible if the source of a hyperandrogenic state, as well as metabolic abnormalities are found in women with acne.

This paper describes a clinical case of status asthmaticus in a gerl adolescent with bronchial asthma. Status asthmaticus terminated in death. Morpologic data is present. This case is illustration of fact that diabetes mellitus type 1 is predictor of status asthmaticus in children.

Seventy-seven emergency care physicians and 33 medical interns were anonymously questioned. The respondents were established to be equally aware of risk factors for decompensation of hypertension. Those asked in both groups do not consider physicians and tolerance to treatment to play a significant role in loss of blood pressure control.