Investigation of low baby's breath (Gypsophila muralis) herb: anatomical structure and chemical composition


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Abstract

Introduction. Low baby's breath (Gypsophila muralis L.) is an annual herbaceous plant that is widely distributed in Eurasia. It is not picky about soils, grows on sands, roads, and wastelands. It often supplanted by other species. Its decorative forms run wild easily. It has never been used in official and folk medicine, but in recent years it has been applied for decorative purposes. Objective: to investigate the anatomical structure and chemical composition of low baby's breath herb. Material and methods. The investigation object was dried low baby's breath herb collected on fallow lands in the vicinity of the village of Retkino, Ryazan Region. Morphological and anatomical analyses were carried out in accordance with the requirements of the 14th Edition of the Russian Federation's State Pharmacopoeia. The chemical composition of the herb was examined for ecdysteroids and polyphenolic compounds by HPLC on a Gilson-305 chromatograph with a UV detector. Results. The structure of the vegetative and generative organs of low baby's breath was investigated. There was evidence that its raw material contained ecdysteroids (ecdysterone, polypodine B) and polyphenolic compounds (caffeic, gallic, chicory, ferulic, neochlorogenic acids, vicenin, catechin, coumarin, epigallocatechin gallate, lutein-7-glucosamine, hesperidin, and rutin. Conclusion. Low baby's breath can and must be used as a highly effective source of ecdysteroids and polyphenolic compounds.

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About the authors

Sergey Vasilyevich Darmogray

Academician I.P. Pavlov Ryazan State Medical University

Email: pharmacognosia_rzgmu@mail.ru
Head of the Department of Pharmacognosy

Natalia Stanislavovna Erofeeva

Academician I.P. Pavlov Ryazan State Medical University

Email: natalia_erofeeva_ryazan@mail.ru
Senior Lecturer of the Department of Pharmacognosy

Tatyana Olegovna Ostrikova

Academician I.P. Pavlov Ryazan State Medical University

Email: tostrikova0@gmail.com
Assistant of the Department of Pharmacognosy

Vasily Nikolaevich Darmogray

Academician I.P. Pavlov Ryazan State Medical University

Email: pharmacognosia_rzgmu@mail.ru
Professor of the Department of Pharmacognosy

Valentina Anatolyevna Morozova

Academician I.P. Pavlov Ryazan State Medical University

Email: vmorozova16@mail.ru
Senior Lecturer of the Department of Pharmacognosy

Alla Sergeevna Lizunova

Academician I.P. Pavlov Ryazan State Medical University

Email: lizunova-alla@mail.ru
Associate Professor of the Department of Pharmacognosy

Nadezhda Feliksovna Darmogray

Regional State Budget Professional Educational Institution «Ryazan Medical College»

Email: nadin.darmogray@gmail.com
lecturer

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