Selenium and selenium-containing drugs: importance for the body and prevention of various diseases


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Abstract

Introduction. Selenium is a trace element with pronounced catalytic properties. It is an important element for maintaining a healthy physiological state of the body. Selenium is involved in the regulation of immune system functions. Decreased selenium levels in patients with heart failure is associated with a deterioration of exercise tolerance, quality of life, and an unfavorable prognosis. Selenium deficiency causes irreversible damage in brain depletion. Selenium intake in physiological doses is crucial for human health and reproductive functions. Objective of the study. To study the literature data on Russian and foreign researches of significance of selenium and selenium-containing preparations for the organism and their role in prevention of various diseases. Material and methods. The review-analytical research of 6 Russian and 23 foreign articles was carried out. They were published in the period from 1994 till 2021. Results. It has been established that the biological activity of selenium is determined not only by the dose, but also by the chemical forms of the trace element. Its anticarcinogenic and cardioprotective effects essentially depend on them. It was found that Se exists in 2 forms: inorganic (selenite and selenite) and organic (selenomethionine and selenocysteine). The organic form of selenium, selenocysteine, is more bioavailable than other selenium derivatives. The above-ground part of the plant Astragalus woolly-flowered is a source of selenocysteine. It is used to manufacture SELENBIO for women vitamin-mineral complex. Important components of SELENBIO for women are also vitamins C, E and zinc. Conclusion. Components of SELENBIO for women are mutually complementary and reinforce each other's action. All together they provide a powerful total antioxidant effect, reliable protection of the female body from cardiovascular, hormonal, oncological diseases, pathology of the musculoskeletal system, while delaying the aging process, preserving the beauty and health of the skin, hair and nails.

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D. V Dedov

Tver State Medical University of the Ministry of Health of the Russian Federation; Tver Regional Clinical Cardiology Dispensary

Email: dedov_d@inbox.ru
4, Sovetskaya str., Tver, 170100, Russian Federation; 19, Komsomolsky Avenue, Tver, 170041, Russian Federation

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