Vitamins, iron, zinc, selenium, selenium-containing drugs in the complex prevention of complications and treatment of patients with COVID-19

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Abstract

Introduction. COVID-19 disease is associated with an unfavourable prognosis, high mortality of patients, especially if immunity is compromised. Obviously, the issue of comprehensive prevention of complications and treatment of patients with COVID-19 using vitamins, minerals, selenium and selenium-containing drugs is not fully understood and needs to be discussed in more detail. Objective: to study Russian and foreign literature data on the application of vitamins, minerals, selenium-containing drugs in complex prophylaxis of complications and treatment of patients with COVID-19. Material and methods. The review-analytical study of 2 Russian and 30 foreign articles, published in 2011-2021, was carried out. Results. In patients with COVID-19, nutritional and immune system disorders have been identified. A balanced diet including vitamins A, B, C, D, E, iron, zinc and selenium was associated with better treatment results in these patients. They found an association between the nutritional status of the population and the severity of the course of COVID-19. Noted the importance of selenium for life, immune system function, prevention of infectious diseases. Presented the antioxidant, anti-inflammatory, antiviral properties of selenium in COVID-19. Inorganic forms of selenium had high toxicity. Organic forms of selenium (selenocysteine) are more promising for use. The plant Astragalus dasyanthus Pall. has shown useful properties: its accumulation of organic selenium from soil, its content of minerals and antioxidants necessary for humans (vitamins A, E, C, amino acids, bioflavonoids, polysaccharides, terpenes). This plant was used to manufacture the SELENBIO for women vitamin and mineral complex. Conclusion. The prescription of vitamins, minerals, selenium and selenium-containing drugs to patients with COVID-19 undoubtedly requires an individual approach, assessment of the initial trace element content in the body, analysis of the clinical symptoms and severity of the new coronavirus infection and consideration of comorbid diseases already present in the patient.

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About the authors

Dmitry Vasilyevich Dedov

Tver State Medical University of the Ministry of Health of the Russian Federation; Regional Clinical Cardiological Dispensary

Email: dedov_d@inbox.ru
Doctor of Medical Sciences, Professor of the Department; cardiologist Russian Federation,

Sevara Dzhurabekovna Marchenko

The First I.M. Sechenov Moscow State Medical University of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: sevara.marchenko@gmail.com
Candidate of Pharmaceutical Sciences, Associate Professor Russian Federation,

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