Analysis of the pharmaceutical market of drugs containing a sulfanilamide group

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Abstract

Introduction. Antimicrobial resistance (AMR) infections are currently a global public health problem. The global medical community has developed a number of measures to address this issue. One of the promising ways to overcome AMR is to create a new class of antimicrobial drugs by modifying existing drugs that have proven themselves in the treatment of infectious diseases. These parameters correspond to the group of sulfanilamide preparations. To assess the possibility of their use as a basis for modification, it is necessary to study their current range. This analysis is an important step, because the modern pharmaceutical market of the Russian Federation tends to increase the product range. Objective: to study the current range of drugs of the sulfanilamide group on the pharmaceutical market of the Russian Federation in order to identify trends in the direction of creating new drugs based on them. Material and methods. As objects of study, data from the State Register of Medicines were used, which were studied by the method of content analysis. Results. As a result of the content analysis, it was found that, due to their effectiveness in treating a wide range of diseases, drugs of the sulfanilamide group are included in 5 clinical and pharmacological groups of the State Register of Drugs at once. However, the total number of drugs of the sulfanilamide group and their dosage forms is not enough. Conclusion. It was shown that in order to improve the quality of medical care in the treatment of infectious diseases, it is necessary to create new domestically produced chemotherapeutic agents that are effective against microbial pathogens that are resistant to existing antimicrobial drugs. The content analysis performed showed that sulfanilamide group drugs are a promising class for creating new drugs based on them by modifying them.

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About the authors

Natalia Sergeevna Skosyreva

Ural State Medical University of Ministry of Health of Russia

Author for correspondence.
Email: skosyreva.nataly@mail.ru
post-graduate student at the Department of Management and Economics of Pharmacy, Pharmacognosy

Olga Alexandrovna Melnikova

Ural State Medical University of Ministry of Health of Russia

Email: newfarmacia@mail.ru
Doctor of Pharmaceutical Sciences, Professor, associate professor at the Department of Management and Economics of Pharmacy, Pharmacognosy

Mikhail Yurievich Melnikov

Ural State Medical University of Ministry of Health of Russia

Email: sasha-ber73@mail.ru
PhD in Chemical Sciences, associate professor at the Department of Pharmacy and Chemistry

Aleksandr Yurievich Petrov

Ural State Medical University of Ministry of Health of Russia

Email: uniitmp@yandex.ru
Doctor of Pharmaceutical Sciences, Professor, Head of the Department of Pharmacy and Chemistry

References

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Supplementary files

Supplementary Files
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2. Fig. 1. Content analysis of the nomenclature of sulfanilamide drugs of the pharmaceutical market of the Russian Federation

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3. Fig. 2. Percentage by number of countries producing sulfanilamide drugs (in %)

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4. Fig. 3. Analysis of subgroups by number of drugs and types of dosage forms

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5. Fig. 4. Summary results of the content analysis of the nomenclature of sulfanilamide drugs of the pharmaceutical market of the Russian Federation by subgroups

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