Clinical Profile of a patient with vitamin D deficiency in the blood

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Abstract

Introduction. The present work is devoted to the analysis of parameters (social and laboratory data) that allowed us to create a clinical profile of a patient with vitamin D deficiency. It is known that vitamin D is involved not only in the regulation of phosphorus-calcium metabolism, but also has extra-bone effects. However, violations of these processes do not always have specific manifestations that make the doctor and the patient think about vitamin D deficiency. The study found that 64% of patients had vitamin D deficiency in their blood. Considering the above, a doctor of any specialty should remember about the "erased" clinic of vitamin D deficiency and have a certain alertness when diagnosing this condition. Objective: to evaluate the social and laboratory data available in the medical record by compiling a clinical profile of a patient who is being observed in one of the clinics in Tyumen. Material and methods. The work was carried out on the basis of a multidisciplinary clinic of the Tyumen State Medical University in the period 2019-2020. The study included 231 medical records. The D3 content in the blood was determined by laboratory immunological method of quantitative determination of the D3 level in vitro. The ELISA method was used. The results were calculated based on a standard calibration curve. Results. In the course of the study, it was possible to make a clinical profile of the patient depending on the content of vitamin D in the blood. Conclusion. When managing a patient with a particular pathology, determining the level of vitamin D in the blood plays an important role. Since this, among other things, will allow you to approach the treatment and examination of the patient individually.

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About the authors

Yu. V Boldyreva

Federal State Budgetary Educational Institution of Higher Education "Tyumen State Medical University" of the Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: tgma.06@mail.ru

I. A Lebedev

Federal State Budgetary Educational Institution of Higher Education "Tyumen State Medical University" of the Ministry of Healthcare of the Russian Federation

Email: lebedef@mail.ru

E. A Hajiumarova

Federal State Budgetary Educational Institution of Higher Education "Tyumen State Medical University" of the Ministry of Healthcare of the Russian Federation

Email: aminaumara2016@mail.ru

References

  1. Биохимия: учебник. Под ред. Е.С. Северина. 5-е изд., испр. и доп. М.: ГЭОТАР-Медиа, 2014; 768.
  2. Доан Т.М., Александрова В.А., Чурилов Л.П. Дефицит витамина D в тропиках и субтропиках. Крымский журнал экспериментальной и клинической медицины. 2017; 7 (1): 12-6.
  3. Bikle D.D. Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology. 2014; 3: 319-29.
  4. Chun R.F., Peercy B.E., Orwoll E.S. et al. Vitamin D and DBP: The free hormone hypothesis revisited. The J. of Steroid Biochemistry and Molecular Biology. 2014; 144: 132-7.
  5. Holick M.F. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord. 2017; 18: 153-65.
  6. Струков В.И. Гипервитаминоз D и гиперкальциемические состояния. Когда кальций опасен? Пенза, 2014.
  7. Клинические рекомендации. Дефицит витамина D у взрослых: диагностика, лечение и профилактика. Российская ассоциация эндокринологов; ФГБУ «Эндокринологический научный центр». М., 2015.
  8. Бурмистрова Л. А. Физико-химический анализ и биохимическая оценка биологической активности трутневого расплода: дис.. канд. биол. наук. Рыбное, 1999.
  9. Митрофанов Д.В., Будникова Н.В. Содержание деценовых кислот в препаратах трутневого расплода и комбинированных препаратах на его основе. Биомика. 2020; 12 (3): 38993.

Supplementary files

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2. Fig. 1. Distribution of patients by age, %

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3. Fig. 2. Distribution of patients depending on the territory of residence, %

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4. Fig. 3. Distribution of the frequency of requests for medical care depending on the time of year, %

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5. Fig. 4. Assessment of vitamin D levels in the blood, %

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