Development and implementation of a methodology for integrated assessment and prediction of non-compliance risk for HIV-infected patients

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Abstract

Introduction. In the current global situation, HIV-infected persons are still a vulnerable group of the population, therefore it is extremely important that effective preventive measures are developed and taken to ensure their well-being. An integral part of monitoring the effectiveness of preventive measures is the importance of understanding the essence and correct assessment of the risk of non-compliance. A scientifically based assessment of this risk and its prediction can protect HIV-infected people from further complications. This paper presents a method of integral assessment and prediction of the risk of non-compliance with the patient's treatment regimen as a way to control the effectiveness of preventive measures for HIV-infected patients, based on the results of a survey of HIV-infected patients for adherence to treatment and based on the proposed methodological approach.

Objective: to develop a methodological approach to predicting the risk of non-compliance in patients with HIV infection.

Material and methods. A survey was conducted of 200 patients treated at the State Medical Institution "Kuzbass Center for the Prevention and Control of AIDS". The methodological approach to predicting the risk of non-compliance with the treatment regimen by HIV-infected patients is based on taking into account a set of factors affecting the results of therapy of HIV-infected patients.

Results. It has been established that patients with HIV infection, as a rule, do not follow many recommendations of doctors on compliance with the treatment regimen, which significantly reduces the level of adherence to pharmacotherapy. Therefore, the proposed methodology for assessing patients' non-compliance with the treatment regimen and determining risk ranges are aimed at monitoring the effectiveness of preventive measures and increasing its practical significance.

Conclusion. In the evaluation process, a fairly low level of compliance with the treatment regimen was established by patients (the value of the HIV-infected patients' treatment adherence index was 52.5%), which indicates the need to eliminate risk factors for non-compliance by adopting special requirements.

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About the authors

A. G. Petrov

Kemerovo State Medical University

Author for correspondence.
Email: mefc@mail.ru
ORCID iD: 0000-0001-9543-1134

доктор фармацевтических наук, доцент, профессор кафедры фармации

Russian Federation, Voroshilova str., 22a, Kemerovo, 650056

G. T. Glembotskay

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: glembotskaya_g_t@staff.sechenov.ru
ORCID iD: 0000-0002-4193-8973

доктор фармацевтических наук, профессор, профессор кафедры организации и экономики фармации Института фармации им. А.П. Нелюбина

Russian Federation, Trubetskaya str., 8, p. 2, Moscow, 119991

O. V. Khoroshilova

Kemerovo State Medical University

Email: olgakhorosh77@yandex.ru
ORCID iD: 0000-0001-6607-8431

кандидат фармацевтических наук, ассистент кафедры фармации

Russian Federation, Voroshilova str., 22a, Kemerovo, 650056

V. A. Semenikhin

Kemerovo State Medical University

Email: viansem@yandex.ru
ORCID iD: 0000-0003-0517-2154

доктор медицинских наук, профессор кафедры факультетской терапии, профессиональных болезней и эндокринологии

Russian Federation, Voroshilova str., 22a, Kemerovo, 650056

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  7. Petrov A.G., Abramov N.V., Kashatalap V.V., Glembotskaya G.T., Knysh O.I., Sedykh D.Yu., Khoroshilova O.V. Organizational and methodological foundations for improving medical and pharmaceutical care for patients with myocardial infarction: monograph. Kemerovo, 2022; 277.
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