Antimicrobial activity of essential oil fractions of siberian fir and scotch pine
- Authors: Saveleva E.E.1, Efremov A.A.1,2,3, Rukosueva T.V.1, Bulgakova N.A.1, Logunova A.K.1
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Affiliations:
- FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia
- Institute of Space Technologies FRC KSC SB RAS
- Siberian Federal University
- Issue: Vol 73, No 1 (2024)
- Pages: 16-21
- Section: Pharmaceutical chemistry and pharmacognosy
- URL: https://journals.eco-vector.com/0367-3014/article/view/626959
- ID: 626959
Cite item
Abstract
Introduction. Plants of the pine family, growing mainly in the Northern Hemisphere, are of interest both from an economic and medical point of view. The antimicrobial properties of essential oils of coniferous plants are being actively studied.
Objective: to study the antimicrobial activity of the essential oil fractions of Siberian fir and Scotch pine growing in the Krasnoyarsk Territory.
Material and methods. Essential oils were isolated by hydrosteam distillation on an all-metal installation with a Clevenger nozzle. The component composition of the essential oil fractions was determined by gas chromatography-mass spectrometry. The disc diffusion method was chosen to detect the antimicrobial activity of essential oil fractions. The following test cultures were used: Staphylococcus aureus (MSSA), Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa, Candida albicans.
Results. In all fractions of the essential oil of Siberian fir and Scotch pine, monoterpenoids predominate, the dominant components are bornylacetate and pinene, respectively. All fractions of both oils showed antimicrobial activity against Staphylococcus aureus (MRSA), Staphylococcus aureus (MSSA) and Candida albicans. Isolated individually dominant compounds bornylacetate (Siberian fir) and pinene (Scots pine) also showed antimicrobial activity.
Conclusion. The antimicrobial activity of individual fractions of essential oils of Siberian fir and Scotch pine and the dominant components of the fractions against Staphylococcus aureus (MSSA and MRSA), Escherichia coli, Pseudomonas aeruginosa, Candida albicans was studied. The activity of the fractions is largely due to the dominant components. The fractions enriched in monoterpenoids showed the highest activity. The strain of Staphylococcus aureus (MRSA) turned out to be the most sensitive to the fractions of essential oils.
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About the authors
Elena Evgenievna Saveleva
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia
Email: saveleva_ee@mail.ru
ORCID iD: 0000-0002-6963-5851
PhD in pharmaceutical sciences, associate professor, head of the Department of Pharmacy
Russian Federation, Krasnoyarsk, Partizan Zheleznyak str., 1, 660022Alexander Alekseevich Efremov
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia; Institute of Space Technologies FRC KSC SB RAS; Siberian Federal University
Email: aefremov15@mail.ru
ORCID iD: 0009-0004-5946-1140
Doctor of chemical sciences, professor, Researcher at the Laboratory of Fundamental and Personalized Pharmacy, FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia; head of the Department of Complex Processing of Vegetable Raw Materials, Institute of Space Technologies FRC KSC SB RAS; Professor of the Department of Chemistry of the Polytechnic Institute, Siberian Federal University
Russian Federation, Krasnoyarsk, Partizan Zheleznyak str., 1, 660022; Krasnoyarsk, Akademgorodok str., 50, 660036; Krasnoyarsk, Svobodny ave., 82А, 660041Tatiana Vladimirovna Rukosueva
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia
Email: ru-ta@inbox.ru
ORCID iD: 0000-0002-2713-8726
PhD in biological sciences, associate professor at the Department of Microbiology
Russian Federation, Krasnoyarsk, Partizan Zheleznyak str., 1, 660022Nadezhda Anatolyevna Bulgakova
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia
Email: bulgakovana@bk.ru
ORCID iD: 0000-0002-3512-6573
PhD in chemical sciences, associate professor, associate professor at the Department of Pharmacy
Russian Federation, Krasnoyarsk, Partizan Zheleznyak str., 1, 660022Alexandra Konstantinovna Logunova
FSBEI НЕ Prof. V.F. Voino-Yasenetsky KrasSMU MOH Russia
Author for correspondence.
Email: klaleks4@gmail.com
ORCID iD: 0000-0002-1002-1732
3rd year student of the Faculty of Medicine, Psychology and Pharmacy
Russian Federation, Krasnoyarsk, Partizan Zheleznyak str., 1, 660022References
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