Macroand microscopic analysis of the herbal sedative composition
- Authors: Prozhogina Y.E.1, Javakhyan M.A.1,2, Bobkova N.V.3
-
Affiliations:
- All-Russian Scientific Research Institute of Medicinal and Aromatic
- Lomonosov Moscow State University
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 71, No 5 (2022)
- Pages: 18-24
- Section: Pharmaceutical chemistry and pharmacognosy
- URL: https://journals.eco-vector.com/0367-3014/article/view/113743
- DOI: https://doi.org/10.29296/25419218-2022-05-03
- ID: 113743
Cite item
Abstract
Introduction. Solving the problems of psychoemotional health is one of the priorities of modern medicine. An increase in the level of stress and anxiety can be expressed not only in a worsening of psychological well-being, but also in the development of somatic diseases. Sedative medicines are one of the most effective and promising areas of pharmacotherapy.
Objective: to conduct a pharmacognostic analysis of the self-developed sedative medicinal herbs composition to establish the authenticity of the components included to ensure the possibility of introducing the medicine into pharmaceutical practice.
Material and methods. The object of the study is a four-component sedative herbal composition consisting of the herb of motherwort cordial (common motherwort) (Leonuruscardiaca L.), herb of St. John's wort (Hypericumperforatum L.), herb of lemon balm (Melissa officinalis L.) and herb of thyme (Thymus serpyllum L.). Methods - techniques of macro- and microscopic analysis.
Results. The characteristics of the authenticity of the herbal sedative composition, including a description of external signs and microscopic analysis, are determined.
Conclusion. The analysis was carried out which is necessary stage for the possibility of introduction of the medicine into pharmaceutical practice.
Full Text
About the authors
Yulia Eduardovna Prozhogina
All-Russian Scientific Research Institute of Medicinal and Aromatic
Author for correspondence.
Email: yulia-pro93@mail.ru
Applicant for a Degree Candidate of Pharmaceutical Sciences
Marina Arkadyevna Javakhyan
All-Russian Scientific Research Institute of Medicinal and Aromatic; Lomonosov Moscow State University
Email: akopovamarina13@mail.ru
Chief Researcher; Associate Professor of the Department of Pharmaceutical Technology
Natalia Vladimirovna Bobkova
Sechenov First Moscow State Medical University (Sechenov University)
Email: bobkovamma@mail.ru
Professor of Pharmaceutical Natural Sciences Department, Institute of Pharmacy
References
- The State Pharmacopoeia оf The Russian Federation, XIV-ed. [Electronic resource]. Access mode:
- https://femb.ru/record/pharmacopea14 (in Russian)
- Aliev M.A. Problems of epidemiologic research work and prevalence of psychic disorders in modern world. Vestnik nevrologii, psihiatrii i nejrohirurgii. 2017; 8: 9–16. (in Russian)
- Shalnova S.A., Evstifeeva S.E., Deev A.D., Artamonova G.V. et al. The prevalence of anxiety and depression in different regions of the Russian Federation and its association with sociodemographic factors (according to the data of the ESSE-RF study). Terapevticheskij arhiv. 2014; 6 (12): 53–60. doi: 10.17116/terarkh2014861253-60 (in Russian)
- Mitihina I.A., Mitihin V.G., Yastrebov V.S., Limankin O.V. Epidemiological models of the influence of socio-economic factors on the mental health indicators of the population of the Russian Federation in the period 1992–2008. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2012; 4: 4−10 (in Russian)
- Burtscher J., Burtscher M., Millet G.P. (Indoor) isolation, stress, and physical inactivity: Vicious circles accelerated by COVID-19? Scand J. Med. Sci Sports. 2020; 30 (8): 1544–5. doi: 10.1111/sms.13706
- Shah S.M.A., Mohammad D., Qureshi M.F.H., Abbas M.Z., Aleem S. Prevalence, psychological responses and associated correlates of depression, anxiety and stress in a global population, during the coronavirus disease (COVID-19) pandemic. Community Ment Health J. 2021; 57 (1): 101–10. doi: 10.1007/s10597-020-00728-y
- Tokareva M.G., Prozhogina Y.E., Kalenikova E.I., Dzhavakhyan M.A. The analysis of modern Russian market of sedative herbal medicines. Voprosy obespechenija kachestva lekarstvennyh sredstv. 2019; 24 (2): 4–19 (in Russian)
- Medicines in Russia: The VIDAL Guideline, 27-ed. Moscow: Vidal Rus., 2021; 1120 (in Russian)
- Unified structured directory – catalog of medicines for medical use of the Ministry of Health of the Russian Federation [Electronic resource]. Access mode: https://esklp.egisz.rosminzdrav.ru (accessed: 20.11.2021) (in Russian)
- State Register of Medicines of the Ministry of Health of the Russian Federation [Electronic resource]. Access mode: https://grls.rosminzdrav.ru (accessed: 20.11.2021) (in Russian)
- List of vital and essential medicines for Medical Use for 2021: Decree of the Government of the Russian Federation dated 12.10.2019 No.2406-r "On approval of the List of vital and essential medicines for 2020" with amendments made by Decree of the Government of the Russian Federation dated November 23, 2020 No.3073-r, effective from January 1, 2021 (in Russian)
- Bekker R.A., Bykov Yu.V. Spicy and aromatic plants in psychiatry and neurology: a scientific review. Part I. Siberian J. of Life Sciences and Agriculture. 2018; 10 (1): 90–123. doi: 10.12731/wsd-2018-1-90-123 (in Russian)
- Tokareva M.G., Prozhogina Y.E., Kalenikova E.I., Dzhavakhyan M.A. The pharmacognostic and pharmacological aspects of the creating of the new sedative drugs based on medicinal plant raw materials. Voprosy biologicheskoj, medicinskoj i farmacevticheskoj himii. 2018; 21 (3): 3−11. doi: 10.29296/25877313-2018-03-01 (in Russian)
- Martynov A.M., Dargaeva T.D. Micromorphological elements of the "BRONKHOLISAN" herbal medicinal mixture. Mezhdunarodnyj nauchno-issledovatel'skij zhurnal. 2021; 1–3 (103): 73–8. doi: 10.23670/IRJ.2021.103.1.067 (in Russian)
- Mardaryeva K.R., Ovsyannikova T.P. Macroscopic and microscopic analysis of the «Stop-urate» plant composition. Collection of scientific articles of the All-Russian Scientific and practical Conference of students and young scientists with international participation, Irkutsk, 3–4 December. 2020; 97–103 (in Russian)
- Samylina I.A., Ermakova V.A., Bobkova N.V., Anosova O.G. Pharmacognosy. Atlas. Volume 3. Moscow: GEOTAR-Media, 2009; 488 (in Russian)