Physical fatigue and the morfofunctional state of myocardium in experimental chronic stress

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Abstract

The relationship between skeletal muscle fatigue and morpho-functional alterations in the myocardium was analyzed for the first time in Wistar male rats exposed to chronic stress. Post traumatic stress disorder (PTSD) was associated with signs of increased oxidative stress, which apparently induced the changes in cardiomyocyte structural components and the acceleration of skeletal and muscular fatigue.

About the authors

M. V. Kondashevskaya

Research institute of human morphology

Author for correspondence.
Email: marivladiko@mail.ru
Russian Federation, Moscow

V. E. Tseylikman

South Ural State University

Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk

M. V. Komelkova

South Ural State University

Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk

M. S. Lapshin

South Ural State University

Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk

A. P. Sarapultsev

Institute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences;Ural Federal University

Email: marivladiko@mail.ru
Russian Federation, Ekaterinburg;Ekaterinburg

S. S. Lazuko

Educational Establishment Vitebsk State Order of Peoples' Friendship Medical University

Email: marivladiko@mail.ru
Belarus, Vitebsk

O. P. Kuzhel

Educational Establishment Vitebsk State Order of Peoples' Friendship Medical University

Email: marivladiko@mail.ru
Belarus, Vitebsk

E. B. Manukhina

South Ural State University;Institute Of General Pathology And Pathophysiology;University of North Texas Health Science Center

Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk;Moscow;Fort Worth

H. F. Downey

South Ural State University;University of North Texas Health Science Center

Email: marivladiko@mail.ru
Russian Federation, Chelyabinsk;Fort Worth

M. V. Chereshneva

Institute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences

Email: marivladiko@mail.ru
Russian Federation, Ekaterinburg

V. A. Chereshnev

Institute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences;Ural Federal University

Email: marivladiko@mail.ru

academician of the RAS

Russian Federation, Ekaterinburg;Ekaterinburg

References

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