Tribochemical Component of Oxidative Stress Development at Artificial Joints Implantation. Part 4. Use of Lubrication and Antioxidant Action of Bone Fat in Total Hip Implant


Human bone fat possesses expressed lubrication action, essentially reduces the torque moment of various friction units, inhibit formation of toxic free radicals. With the purpose of patient's bone fat use in Movshovich — Gavryushenko hip joint implant an arthro-medullar canal that connect bone marrow cavity and wear bearing surface of implant is present. Axial loadings of this implant cause flow of liquid bone fat via canal to friction unit thus promoting improvement of tribologic parameters and inhibiting the development of free radical reactions. Application of bone fat can reduce or completely block the action of several negative factors that deteriorate outcomes of total joint replacement.

Full Text

Трибохимический компонент развития окислительного стресса при имплантации искусственных суставов. часть 4. использование лубрикационного и антиокислительного действия костного жира в эндопротезе тазобедренного сустава


  1. Raimondi M.T., Vena P., Pietrabissa R. Quantative evaluation of the prosthetic head damage induce by microscopic third-body particles in total hip replacement. J. Biomed. Mater. Res. 2001; 58 (4): 436-448.
  2. Mu Y., Kobayashi T., Sumita M., Yamamoto A., Hanawa T. Metal ion release from titanium with active oxygen species generated by rat macrophages in vitro. J. Biomed. Mater. Res. 2000; 49 (2): 238-243.
  3. Jahan M.S., Wang C., Schwartz G., Davidson J.A. Combined chemical and mechanical effects on free radicals in UHMWPE joint during implantation. J. Biomed. Mater. Res. 1991; 25(8): 1005-1017.
  4. Булгаков В.Г., Гаврюшенко Н.С., Цепалов В.Ф., Шаль- нев А.Н. Трибохимический компонент развития окислительного стресса при имплантации искусственных суставов. Часть 1. Определение радикалообразующей способности частиц износа различных ортопедических материалов. Вестн. травматол. ортопед. 2010; 1: 44-48.
  5. Гаврюшенко Н.С., Булгаков В.Г. Выявление и оценка роли артро-медуллярной связи в функционировании суставов человека (экспериментальное исследование). Вестн. травматол. ортопед. 2001; 2: 72-75.
  6. Gavryushenko N.S. Recommendations with respect to the improvement of lubricating qualities of synovial fluid in artificial joints. Proc. Inst. Mech. grs (part H). 1993; 207: 111-114.
  7. ГОСТ Р 52640-2006. Имплантаты для хирургии. Замещение сустава тотальным эндопротезом. Определение долговечности работы узла трения эндопротеза тазобедренного сустава методом оценки крутящего момента.
  8. James S.P., Blazka S, Merrill E.W., Jasty M., Lee K.R., Bragdon C.R., Harris W.H. Challenge to the concept that UHMWPE acetabular components oxidize in vivo. Biomaterials. 1993; 14 (9): 643-647.
  9. Scholes S.C., Unsworth A. Comparison of friction and lubrication of different hip prostheses. Proc. Inst. Mech. Eng. H. 2000; 214 (1): 49-57.
  10. Bell J., Tipper J.L., Ingham E., Stone M.H., Fisher J. The influence of phospholipid concentration in protein- containing lubricants on the wear of ultra-high molecular weight polyethylene in artificial hip joints. Proc. Inst. Mech. Eng. H. 2001; 215 (2): 259-63.
  11. Foy J.R., Williams P.F. 3rd, Powell G.L., Ishihara K., Nakabayashi N., LaBerge M. Effect of phospholipidic boundary lubrication in rigid and compliant hemiarthroplasty models. Proc. Inst. Mech. Eng. H. 1999; 213 (1): 5-18.
  12. Andersson G.B., Freeman M.A.V., Swanson S.A.V. Loosening of the cemented acetabular cap in total hip replacement. J Bone Jt Surg Br. 1972; 54 (4): 590-599.
  13. Nassutt R., Wimmer M.A., Schneider E., Morlock M.M. The influence of resting periods on friction in the artificial hip. Clin. Orthop. Relat. Res. 2003; (407): 127-138.
  14. Morrell K.C., Hodge W.A, Krebs D.E., Mann R.W. Corroboration of in vivo cartilage pressures with implications for synovial joint tribology and osteoarthritis causation. Proc. Natl. Acad. Sci USA. 2005; 102 (41): 14819-14824.
  15. Catelas I., Medley J.B., Campbell P.A., Huk O.L., Bobyn J.D. Comparison of in vitro with in vivo characteristics of wear particles from metal-metal hip implants. J. Biomed. Mater. Res. B Appl. Biomater. 2004; 70 (2): 167-178.



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