Nachal'nye etapy distraktsionnogo osteogeneza

Abstract


Analysis of literature data dedicated to the study of distraction osteosynthesis is presented. In accordance with the ideas of the mechanisms of reparative regeneration in distraction osteosynthesis, the main factors responsible for the triggering of reparative regeneration are artificially created tissue “deficit” and tension-stress effect on the vascular network that was formed during the latent period. Consecutive local effect of growth factors and other peptide regulators provides sufficient level of reparative osteogenesis within the whole distraction period. The volume and quality of newly formed bone tissue depend upon the spatial and temporal characteristics of distraction as well as on the potentialities of concrete individual.

About the authors

S. P Mironov

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia


N. P Omel’yanenko

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia


I. N Karpov

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia

Email: igorkarpoff@mail.ru

A. V Ivanov

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia


A. V Khlystova

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia


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