Effect of Tourniquet upon Development of Intra- and Postoperative Complications in Total Knee Replacement in Patients Treated with Pradaxa

Abstract


Results of comparative study of intra- and postoperative blood loss, rate of thromboembolic complications at total knee replacement with and without tourniquet application on the background of anticoagulant therapy with Pradaxa. It was shown that application of pneumatic tourniquet considerably decreased blood loss during the most laborious steps of operation but did not decreased the total blood loss and simultaneously increased the risk of thromboembolic complications development in the early postoperative period. Anticoagulant therapy including oral Pradaxa 220mg/day provided the convenience for the patient to continue thromboprophylaxis after discharge that greatly increased its efficacy.

References

  1. Загородний Н.В. Профилактика тромбоэмболических осложнений у ортопедических больных при эндопротезировании крупных суставов //Материалы городского симпозиума «Профилактика тромбоэмболических осложнений в травматологии и ортопедии». - М., 2003. - С. 34-39.
  2. Миронов С.П., Троценко В.В., Андреева Т.М. и др. Современные технологии в травматологии и ортопедии //Съезд травматологов-ортопедов России, 7-й: Тезисы докладов. - Новосибирск, 2002 - С. 447-448.
  3. Abdel-Salam A., Eyres K.S. Effects of tourniquet during total knee arthroplasty. A prospective randomised study //J. Bone Jt Surg. (Br.) - 1995. - Vol. 77. - P. 250-253.
  4. Clarke M.T., Longstaff L., Edwards D., Rushton N. Tourniquet-induced wound hypoxia after total knee replacement //J. Bone Jt Surg. (Br.) - 2001. - Vol. 83. - P. 40-44.
  5. Klenerman L. Is a tourniquet really necessary for total knee replacement? //J. Bone Jt Surg. (Br.) - 1995. - Vol. 77. - P. 174-175.
  6. Li B. Recent postoperative evaluation of tourniquet in total knee replacement surgery //J. Surg. - 2008. - Vol. 46. - P. 1054-1057.
  7. Nadler S.B., Hidalgo J.U., Bloch T. Prediction of blood volume in normal human adults // Surgery. - 1962. - Vol. 57. - P. 224-232.
  8. Parmet J.L., Horrow J.C., Berman A.T. et al. The incidence of large venous emboli during total knee arthroplasty without pneumatic tourniquet use //Anesth. Analg. - 1998. - Vol. 87. - P. 439-444.
  9. Sehat K.R., Evans R.L., Newman J.H. Hidden blood loss following hip and knee arthroplasty: correct managent of blood loss shoud take hidden loss into account //J. Bone Jt Surg. (Br.) - 2004. - Vol.86. - P. 561-565.
  10. Tan J. Clinical impact on invisible blood loss in total hip and total knee replacement surgery //Chin. J. Orthop. (Chin). - 2006. - Vol. 26. - P. 323-326.

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Copyright (c) 2011 Girkalo M.V., Puchin'yan D.M., Voskresenskiy O.Y., Derevyanov A.V., Mandrov A.V., Girkalo M.V., Puchinyan D.M., Voskresenskyi O.Y., Derevyanov A.V., Mandrov A.V.

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