Effect of Tourniquet upon Development of Intra- and Postoperative Complications in Total Knee Replacement in Patients Treated with Pradaxa

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Abstract

Results of comparative study of intra- and postoperative blood loss, rate of thromboembolic complications at total knee replacement with and without tourniquet application on the background of anticoagulant therapy with Pradaxa. It was shown that application of pneumatic tourniquet considerably decreased blood loss during the most laborious steps of operation but did not decreased the total blood loss and simultaneously increased the risk of thromboembolic complications development in the early postoperative period. Anticoagulant therapy including oral Pradaxa 220mg/day provided the convenience for the patient to continue thromboprophylaxis after discharge that greatly increased its efficacy.

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