Chondrosarcoma in Children

Full Text


Treatment experience was analyzed in 77 patients (aged from 1 to 17 years) with chondrosarcoma. All patients were under treatment at the Scientific Research Institute of Pediatric Oncology and Hematology during the period from 1982 to 2008. In 36 patients including patients with second degree of malignancy (main group) new treatment protocol that provided application of polychemotherapy with regard to the risk group was used. Second degree of malignancy was determined by the degree of DNA ploidy and proliferative tumor cells activity by flow cytophotometry data. Forty one patients (control group) were treated according to the routine protocol. It has been shown that early application of polychemotherapy enabled to expand the indications to organ saving surgical interventions and to increase 5-years relapse-free survival at unfavo-rable forms of chondrosarcoma up to 75±7.8%.


  1. Алиев М.Д., Соловьев Ю.Н., Харатишвили Т.К. и др. Хондросаркома кости. - М., 2006.
  2. Волков М.В. Болезни костей у детей. - 2-е изд. - М., 1985.
  3. Кочергина Н.В. Лучевая диагностика и общие принципы дифференциальной рентгенодиагностики опухолей костей и мягких тканей. - М., 1994. - С. 121-127.
  4. Соловьев Ю.Н. Опухоли костей //Патологоанатомическая диагностика опухолей человека. - Т. 2. - М., 1993. - С. 482-523.
  5. Харатишвили Т.К. Хондросаркома кости (клиника, диагностика, лечение, прогноз): Дис. … д-ра мед. наук. - М., 2000.
  6. Delepine G., Delipine F., Guikov E. Degeneration of be-ning cartilage tumours: diagnosis and prognosis //J. Bone Jt Surg. - 2005. - Vol. 87B, Suppl. 2. - P. 105.
  7. Moussavi-Harami H., Rhomberg R. What's new in musculoskeletal oncology //J. Bone Jt Surg. - 2007. - Vol. 89A. - P. 1403-1407.



Abstract: 84


CrossRef: 1

  1. Dorokhin MV, Kuznetsov YM, Lesnikov VP, Zdoroveyshchev AV, Demina PB, Erofeeva IV. Studies of Thermoelectric Properties of Superlattices Based on Manganese Silicide and Germanium. Physics of the Solid State. 2019;61(12):2348. doi: 10.1134/S1063783419120102


Article Metrics

Metrics Loading ...



  • There are currently no refbacks.

Copyright (c) 2009 Eco-Vector

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies