Conceptual Model of Spine Osteochondropathy Pathogenesis

Abstract


The new direction in study of spine osteochondropathy pathogenesis was worked out from the point of systemic approach. The disease is considered as continuous dysplastic-dystrophic process. The base of this process is a structural anomaly of the end-plates of vertebral body that changes morphogenesis of the vertebral segment. Subsequent clinical course is determined by anatomic-biomechanic characteristics of the affected zone, peculiarities of spine configuration in the saggital plane as well as by the variants of disorders in vertebral body shape formation.

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