Surgery features of aneurysmal bone cysts of the spine in children

Cover Page

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access


The article presents the long-term experience of stepwise surgical treatment of pediatric patients with aneurysmal cysts of the spine. The considered material is based on the data of long-term results and various approaches to the resection technique of pathological neoplasm; each approach takes into account the localization, lesion volume, spine growth potential, neurological status, secondary spinal deformity.

Full Text

Restricted Access

About the authors

Aleksandr A. Snetkov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Author for correspondence.
ORCID iD: 0000-0001-5837-9584


Russian Federation, 10 Priorova str., Moscow, 127299

Roman S. Gamayunov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics


traumatologist – orthopedist

Russian Federation, 10 Priorova str., Moscow, 127299

Alexander A. Kuleshov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

ORCID iD: 0000-0002-9526-8274
SPIN-code: 7052-0220


Russian Federation, 10 Priorova str., Moscow, 127299

Sergey V. Kolesov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

ORCID iD: 0000-0001-9657-8584
SPIN-code: 1989-6994

MD, PhD, prof

Russian Federation, 10 Priorova str., Moscow, 127299

Aleksandra D. Akinshina

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

SPIN-code: 8740-6190


Russian Federation, 10 Priorova str., Moscow, 127299


  1. Desai SB, O’Brien C, Shaikh R, et al. Multidisciplinary management of spinal aneurysmal bone cysts: a single-center experience. Interv Neuroradiol. 2019;25(5):564–569. doi: 10.1177/1591019919848130
  2. Capanna R, Campanacci DA, Manfrini M. Unicameral and aneurysmal bone cysts. Orthop Clin North Am. 1996;27(3):605–614.
  3. Gibbs CJ, Hefele M, Peabody T. Aneurysmal bone cyst of the extremities. Factors related to local recurrence after curettage with a high-speed burr. J Bone Jt Surg Am. 1999;81:1671–1678.
  4. Bollini G, Jouve JL, Cottalorda J, et al. Aneurysmal bone cyst in children: analysis of twenty-seven patients. J Pediatr Orthop B. 1998;7(4):274–285. doi: 10.1097/01202412-199810000-00005
  5. Rapp TB, Ward JP, Alaia MJ. Aneurysmal bone cyst. J Amer Acad Ortho Surg. 2012;20(4):233–241. doi: 10.5435/JAAOS-20-04-233
  6. Ameli NO, Abbassioun K, Saleh H, Eslamdoost A. Aneurysmal bone cysts of the spine. Report of 17 cases. J Neurosurg. 1985;63(5):685–690. doi: 10.3171/jns.1985.63.5.0685
  7. Beiner JM, Sastry A, Berchuck M, et al. An aneurysmal bone cyst in the cervical spine of a 10-year old girl: a case report. Spine (Phila Pa 1976). 2006;31(14):E475–479. doi: 10.1097/01.brs.0000222126.91514.cb
  8. Ropper AE, Cahill KS, Hanna JW, et al. Primary vertebral tumors: a review of epidemiologic, histological, and imaging findings, Part I: benign tumors. Neurosurgery. 2012;70(1):211–219; discussion 219. doi: 10.1227/NEU.0b013e31822d5f17
  9. Papagelopoulos PJ, Currier BL, Shaughnessy WJ, et al. Aneurysmal bone cysts of the spine: management and outcome. Spine (Phila Pa 1976). 1998;23(5):621–628. doi: 10.1097/00007632-199803010-00018
  10. Dormans JP, Hanna BG, Johnston DR, Khurana JS. Surgical treatment and recurrence rate of aneurismal bone cysts in children. Clin Orthop Relat Res. 2004;(421):205–211. doi: 10.1097/01.blo.0000126336.46604.e1
  11. Voronovich IR, Pashkevich LA. Opukholi pozvonochnika. Minsk: BelTsNII; 2000. (In Russ).
  12. Zatsepin ST. Kostnaya patologiya vzroslykh: rukovodstvo dlya vrachei. Moscow: Meditsina; 2001. (In Russ).
  13. Hay MC, Paterson D, Taylor TK. Aneurysmal bone cysts of the spine. J Bone Joint Surg Br. 1978;60-B(3):406–411. doi: 10.1302/0301-620X.60B3.681419
  14. Schaffer L, Kranzler L, Siqueira E. Aneurysmal bone cyst of the spine. A case report. Spine (Phila Pa 1976). 1985;10(4):390–393. doi: 10.1097/00007632-198505000-00017
  15. Sebaaly A, Ghostine B, Kreichati G, et al. Aneurysmal bone cyst of the cervical spine in children: a review and a focus on available treatment options. J Pediatr Orthop. 2015;35(7):693–702. doi: 10.1097/BPO.0000000000000365
  16. Novais EN, Rose PS, Yaszemski MJ, Sim FH. Aneurysmal bone cyst of the cervical spine in children. J Bone Joint Surg Am. 2011;93(16):1534–1543. doi: 10.2106/JBJS.J.01430
  17. Khalil I, Alaraj A, Otrock Z, et al. Aneurysmal bone cyst of the cervical spine in a child: case report and review of the surgical role. Surg Neurol. 2006;65(3):298–303.
  18. Boriani S, De Iure F, Campanacci L, et al. Aneurysmal bone cyst of the mobile spine: report on 41 cases. Spine (Phila Pa 1976). 2001;26(1):27–35. doi: 10.1097/00007632-200101010-00007
  19. Lastikka M, Aarnio J, Helenius I. Instrumented cervical spinal fusions in children: indications and outcomes. J Child Orthop. 2017;11(6):419–427. doi: 10.1302/1863-2548.11.170115.
  20. de Kleuver M, van der Heul RO, Veraart BE.Aneurysmal bone cyst of the spine: 31 cases and the importance of the surgical approach. J Pediatr Orthop B. 1998;7(4):286–292. doi: 10.1097/01202412-199810000-00006
  21. Vogel LC, Lubicky JP. Cervical spine fusion: not protective of cervical spine injury and tetraplegia. Am J Orthop. 1997;26(9):636–640.
  22. Seller K, Jäger M, Krämer R, et al. Occurrence of a segmental kyphosis after laminectomy of C2 for an aneurysmatic bone cysts—course and treatment strategy. Z Orthop Ihre Grenzgeb. 2004;142(1):83–87. (In German). doi: 10.1055/s-2004-817659
  23. Bell DF, Walker JL, O’Connor G, Tibshirani R. Spinal deformity after multiple-level cervical laminectomy in children. Spine (Phila Pa 1976). 1994;19(4):406–411. doi: 10.1097/00007632-199402001-00005
  24. Yasuoka S, Peterson HA, MacCarty CS. Incidence of spinal column deformity after multilevel laminectomy in children and adults. J Neurosurg. 1982;57(4):441–445. doi: 10.3171/jns.1982.57.4.0441
  25. Naumov DG, Speranskaya EA, Mushkin MA, et al. Spinal aneurysmal bone cyst in children: systematic review of the literature. Hirurgiâ pozvonočnika (Spine Surgery). 2019;16(2):49–55. doi: 10.14531/ss2019.2.49-55
  26. Mushkin AYu, Mal’chenko OV. Onkologicheskaya vertebrologiya: izbrannye voprosy. Novosibirsk; 2012. (In Russ).
  27. Papagelopoulos PJ, Choudhury SN, Frassica FJ, et al. Treatment of aneurysmal bone cysts of the pelvis and sacrum. J Bone Joint Surg Am. 2001;83(11):1674–1681. doi: 10.2106/00004623-200111000-00009
  28. Cisneros AJ, Gomez CH, Benedicto FC, et al. Aneurysmal bone cyst of the ischium. Int Orthop. 1985;9(1):49–54. doi: 10.1007/BF00267037
  29. De Cristofaro R, Biagini R, Boriani S, et al. Selective arterial embolization in the treatment of aneurysmal bone cyst and angioma of bone. Skeletal Radiol. 1992;21(8):523–527. doi: 10.1007/BF00195235
  30. Green JA, Bellemore MC, Marsden FW. Embolization in the treatment of aneurysmal bone cysts. J Pediatr Orthop. 1997;17(4):440–443.
  31. Kónya A, Szendröi M. Aneurysmal bone cysts treated by superselective embolization. Skeletal Radiol. 1992;21(3):167–172. doi: 10.1007/BF00242130
  32. Murphy WA, Strecker EB, Schoenecker PL. Transcatheter embolisation therapy of an ischial aneurysmal bone cyst. J Bone Joint Surg Br. 1982;64(2):166–168. doi: 10.1302/0301-620X.64B2.7068734
  33. Guibaud L, Herbreteau D, Dubois J, et al. Aneurysmal bone cysts: percutaneous embolization with an alcoholic solution of zein: series of 18 cases. Radiology. 1998;208(2):369–373. doi: 10.1148/radiology.208.2.9680561.
  34. Barbanti-Brodano G, Girolami M, Ghermandi R, et al. Aneurysmal bone cyst of the spine treated by concentrated bone marrow: clinical cases and review of the literature. Eur Spine J. 2017;26(Suppl 1):158–166. doi: 10.1007/s00586-017-4978-x
  35. Boriani S, Lo SF, Puvanesarajah V, et al. Aneurysmal bone cysts of the spine: treatment options and considerations. J Neurooncol. 2014;120(1):171–178. doi: 10.1007/s11060-014-1540-0
  36. Gushcha AO, Konovalov NA, Arestov SO, et al. Surgical treatment of primary spinal tumors: tactics and results. Hirurgiâ pozvonočnika (Spine Surgery). 2015;12(3):72–82. doi: 10.14531/ss2015.3.72-82
  37. Shiels WE 2nd, Mayerson JL. Percutaneous doxycycline treatment of aneurysmal bone cysts with low recurrence rate: a preliminary report. Clin Orthop Relat Res. 2013;471(8):2675–2683. doi: 10.1007/s11999-013-3043-2
  38. Doyle A. Recurrent aneurysmal bone cyst of the cervical spine in childhood treated with doxycycline injection. Skeletal Radiol. 2015;44(4):609–612. doi: 10.1007/s00256-014-2027-y
  39. Tonomura ET, Ramos P, Hemais PM, et al. Aneurysmal bone cyst at C2. Imaging evaluation after intralesional injection of calcitonin and methylprednisolone. Arq Neuropsiquiatr. 2008;66(3B):711–715. doi: 10.1590/s0004-282x2008000500020
  40. Rai AT, Collins JJ. Percutaneous treatment of pediatric aneurysmal bone cyst at C1: a minimally invasive alternative: a case report. AJNR Am J Neuroradiol. 2005;26(1):30–33.
  41. D Kieser DC, Mazas S, Cawley DT, et al. Bisphosphonate therapy for spinal aneurysmal bone cysts. Eur Spine J. 2018;27(4):851–858. doi: 10.1007/s00586-018-5470-y
  42. Weinstein R, Roberson P, Manolagas S. Giant osteoclast formation and long-term oral bisphosphonate therapy. Engl J Med. 2009;360(1):53–62. doi: 10.1056/NEJMoa0802633
  43. Tsai JC, Dalinka M, Fallon M, et al. Fluid–fluid level: a nonspecific finding in tumors of bone and soft tissue. Radiology. 1990;175(3):779–782. doi: 10.1148/radiology.175.3.2160676
  44. Vergel De Dios AM, Bond JR, Shives TC, et al. Aneurysmal bone cyst. A clinicopathologic study of 238 cases. Cancer. 1992;69(12):2921–2931. doi: 10.1002/1097-0142(19920615)69:12<2921::aid-cncr2820691210>;2-e
  45. Protas M, Jones LW, Sardi JP, et al. Cervical spine aneurysmal bone cysts in the pediatric population: a systematic review of the literature. Pediatr Neurosurg. 2017;52(4):219–224. doi: 10.1159/000475820

Supplementary files

Supplementary Files
1. Fig. 1. Puncture of aneurysmal cyst C4-5 with measurement of pressure in mm water column

Download (238KB)
2. Fig. 2. 13-year-old patient. The 8-month result of the injection treatment of C2 arch

Download (151KB)
3. Fig. 3. CT and MRI examinations upon admission

Download (227KB)
4. Fig. 4. CT and MRI results after 5 months of puncture treatment with less pronounced stenosis of the spinal canal

Download (396KB)
5. Fig. 5. X-ray after surgery; the postoperative wound

Download (259KB)
6. Fig. 6. CT scan of the operation area in 1.5 years after surgery

Download (310KB)



Abstract: 203

PDF (Russian): 2


Article Metrics

Metrics Loading ...



  • There are currently no refbacks.

Copyright (c) 2021 Eco-Vector

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies