Modern lower extremity alignment philosophies in total knee arthroplasty
- Authors: Airapetov G.A.1,2, Zagorodniy N.V.1,3, Daniliyants A.A.1,2, Dzampaev K.A.1, Al Kafavin A.H.1, Akhmat A.A.1, Samkovich D.A.1,2
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Affiliations:
- Peoples' Friendship University of Russia named after Patrice Lumumba
- City Clinical Hospital № 31 named after Academician G.M. Savelyeva
- Priorov National Medical Research Center of Traumatology and Orthopedics
- Issue: Vol 33, No 2 (2026)
- Pages: 416-427
- Section: SCIENTIFIC REVIEWS
- Submitted: 06.04.2025
- Accepted: 16.08.2025
- Published: 12.11.2025
- URL: https://journals.eco-vector.com/0869-8678/article/view/678181
- DOI: https://doi.org/10.17816/vto678181
- EDN: https://elibrary.ru/EWPDCO
- ID: 678181
Cite item
Abstract
Total knee arthroplasty is the primary treatment method for advanced stages of knee osteoarthritis. However, according to the published data, 10%–20% of patients are dissatisfied with the surgical outcome. To improve the results of knee arthroplasty, various lower extremity alignment techniques have been developed and proposed for clinical use over several decades. The review aimed to analyze contemporary techniques of lower extremity alignment in total knee arthroplasty. Scientific data was searched using the Scopus and PubMed databases, the ResearchGate platform, and the eLibrary electronic scientific database. Publications in both Russian and English were retrieved and analyzed. Each alignment philosophy has its own advantages and limitations. The most widely discussed alignment concepts include mechanical alignment, anatomical alignment (systematic techniques aimed at achieving a neutral axis), adjusted mechanical alignment, restricted kinematic alignment (hybrid techniques), kinematic alignment, and functional alignment (personalized techniques). With a more detailed understanding of knee anatomy, kinematics, and the identification of different knee phenotypes, some surgeons advocate the use of hybrid and personalized lower extremity alignment strategies that take into account the constitutional anatomy of the knee joint. Available scientific data indicates that long-term outcomes after total knee arthroplasty using these approaches are either superior to or comparable with those achieved using the classical mechanical alignment philosophy. Nevertheless, the modern alternative axis alignment techniques described in this review are aimed at improving the outcomes of total knee arthroplasty. However, because of insufficient data on long-term implant survivorship, further time and research are required to fully assess the feasibility and appropriateness of their use in orthopedic surgical practice.
Full Text
About the authors
Georgii A. Airapetov
Peoples' Friendship University of Russia named after Patrice Lumumba; City Clinical Hospital № 31 named after Academician G.M. Savelyeva
Email: airapetovga@yandex.ru
ORCID iD: 0000-0001-7507-7772
SPIN-code: 7333-6640
MD, Dr. Sci. (Medicine), Professor
Russian Federation, Moscow; MoscowNikolay V. Zagorodniy
Peoples' Friendship University of Russia named after Patrice Lumumba; Priorov National Medical Research Center of Traumatology and Orthopedics
Email: zagorodniy51@mail.ru
ORCID iD: 0000-0002-6736-9772
SPIN-code: 6889-8166
MD, Dr. Sci. (Medicine), Professor, Academician of the Russian Academy of Sciences
Russian Federation, Moscow; MoscowArmen A. Daniliyants
Peoples' Friendship University of Russia named after Patrice Lumumba; City Clinical Hospital № 31 named after Academician G.M. Savelyeva
Author for correspondence.
Email: armendts@mail.ru
ORCID iD: 0000-0001-6692-0975
SPIN-code: 9880-2555
Russian Federation, Moscow; Moscow
Konstantin A. Dzampaev
Peoples' Friendship University of Russia named after Patrice Lumumba
Email: kostya199921@gmail.com
ORCID iD: 0009-0008-4190-3114
SPIN-code: 5191-4314
Russian Federation, Moscow
Anjum H.A. Al Kafavin
Peoples' Friendship University of Russia named after Patrice Lumumba
Email: anjum.hasan@mail.ru
ORCID iD: 0009-0005-7329-4446
Russian Federation, Moscow
Abdoulaye A. Akhmat
Peoples' Friendship University of Russia named after Patrice Lumumba
Email: dr.ahmataa@gmail.com
ORCID iD: 0009-0000-3654-2408
Russian Federation, Moscow
Dmitry A. Samkovich
Peoples' Friendship University of Russia named after Patrice Lumumba; City Clinical Hospital № 31 named after Academician G.M. Savelyeva
Email: dmitry.samkovitch@gmail.com
ORCID iD: 0000-0001-5770-7304
Russian Federation, Moscow; Moscow
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