Vol XXXIV, No 3-4 (2002)

Some lesions were revealed in the system of oxidation mitochondrial phosphorylation in Fredreich disease, as well as their correlation with the disease course at its different clinical variants. A vivid tendency has been traced to normalization of these cytochemical indices after single treatment by medicines, stabilizing mitochondrial functions.

Some factors, enfluencing multiple sclerosis development, have been studied. Connection of tire disease with living close to metallurgical plants has been confirmed, as well as with prevailing meat products in food and with craniocerebral trauma. For the first time association of multiple sclerosis with infectionous eye diseases has been revealed, as well us with soft tissue absesses, critical dental caries, with contact with birds and with age of a father (senior than 31 y.o.) at the moment of a patient birth. The factors, determining unfavourable course of MS are: craniocerebral trauma without loss of consciousness, contact with agricultural animals, prevailing meat products in nutrition of persons at the age of untill 15 y.o. and disease beginning with cerebellar symptomatology.

A complex clinico-instrumental and immunogenetic study has been performed in 34 patients with different forms of infantile cerebral palsy in Kazan population. HLA-typing has revealed a reliable disease association with antigen B₁₃. The control group was made up of 115 healthy patients. For the first time a comparable risk criteria has been counted: if a patient has B₁₃ antigen — risk of infantile cerebral paralysis development increases by 3.55 times. Contribution of HLA-B13 associated gene into genesis of the disease makes up not less than 11,6%. The study results testify to heridatary mechanisms envolvement into etiopathogenesis of infantile cerebral paralysis and demand further study of genetic peculiarities of «susceptibility» genome to different harmful factors.

Changes of caused potentials at hemorrhagic fever with renal syndrome have been studied, as well as correlation of these indices to EEG data. Mathematical and statistical analysis of EEG parameters and caused potentials in convalescents after HFRS showed significant deviations in brain bioelectric activity; these deviations being characterized by a considerable decrease of amplitude characteristics of the EEG basic rhythms with a tendency to rhythm frequency lowering practically in all cerebral cortex regions, prolongation of latent periods and decrease of caused potentials amplitude. Changes in visual caused potentials can indicate to the cerebral demyelinization process. This correlation analysis has revealed an interchange between different electrophysiologic characteristics.

In the International Classification of Epilepsies and Epileptic Syndromes in 1989 [7], syndromes of both partial and generalized and symptomatic, cryptogenic and idiopathic epilepsy are distinguished. The latter are characterized as “diseases not caused by obvious causes, with the exception of the alleged hereditary predisposition and occur in 25-30% of all epilepsy cases [2]. Idiopathic generalized epilepsies (IGE) are characterized by such common features as the onset of seizures mainly in childhood and adolescence, a high incidence of epilepsy among relatives, the absence of any organic brain disease that causes epilepsy, and focal symptoms in the neurological status, and normal intelligence of patients. , absence of gross morphological changes in the brain during neuroimaging. The IGE is also characterized by the presence of a triad of primary generalized seizures (absences, myoclonic paroxysms and generalized seizures) in any combination, registration on the EEG in the interictal period of spike-wave and polyspike-wave epileptiform activity and the possibility of arresting all seizures (especially valproate) [ 2].

The problem of the meaning of life is connected with the general problem of the Universe, its place in the general development of the Universe, the evolution of man and mankind, the specific meaning of life of each person - with the satisfaction of his basic needs, in particular biological, social and spiritual. The meaning of every person's life is determined by the desire for continuous self-improvement, while if the person himself improves, then the whole of humanity is also improved.

The problem of rehabilitation treatment of patients who have suffered a cerebral stroke is extremely relevant due to its widespread prevalence, high rates of mortality and disability. One of the main reasons for persistent disability are, along with impaired speech function, psychological and social maladjustment, impaired motor functions of patients.

Severe kyphoscoliosis and their complications are one of the causes of disability and mortality in people of working age. After individual correction of gross deformities of the spine, followed by stabilization, regression of severe neurological complications often occurs.

The emergence of the possibility of MRI tomographic diagnostics of neurological diseases stimulated the opening of a new era in the study of syringomyelia. The detection of a frequent combination of Arnold-Chiari malformation with syringomyelia made it possible to revise in many ways the traditional ideas about the nature of this disease.

This study describes 5 cases of epileptic seizures when bathing in a hot bath in children aged 6 months to 2 years. The children were somatically healthy and developing normally. In all cases, the course of epilepsy was mild. The regression of symptoms occurred either after the prescription of antiepileptic drugs, or when the bathing regimen was changed.

The aim of the work was to determine the information content of the figures in the differential diagnosis of migraine and non-migraine headache in children. The need for such a study is dictated by the fact that young children usually cannot accurately characterize headaches, and this makes it difficult to correctly diagnose.

Italian researchers from the University of Tor Vergata have found that some species of Helicobacter pylori bacteria with cytotoxin-associated gene-A (CagA) are significantly more likely to be found in patients who have suffered from stroke associated with atherosclerotic vascular lesions.