Quality assessment of Silybum marianum fruits grown in the Republic of Buryatia
- Authors: Saybel O.L.1, Konyaeva E.A.1, Kulyak O.Y.1, Dul V.N.1, Tsybikova O.M.2, Tsydypov B.D.2
-
Affiliations:
- All-Russian Scientific Research Institute of Medicinal and Aromatic Plants
- Buryat State Agricultural Academy named after V.R. Filippov
- Issue: Vol 27, No 3 (2024)
- Pages: 30-34
- Section: Pharmaceutical chemistry
- URL: https://journals.eco-vector.com/1560-9596/article/view/629323
- DOI: https://doi.org/10.29296/25877313-2024-03-05
- ID: 629323
Cite item
Open Access
Access granted
Abstract
Introduction. Medicines of plant origin are widely used in the complex therapy of various diseases. Among the medicines of plant origin used for the treatment of chronic liver diseases, the most popular are preparations based on Silybum marianum (L.) Gaertn.).
The aim of this work was to Silybum marianum fruits to evaluate the possibility of obtaining raw materials of pharmacopoeial quality in the dry-steppe zone of the Republic of Buryatia.
Material and methods. The object of the study was Silybum marianum fruits of the varieties Debut and Start, obtained from experimental fields in Ivolginsky district of the Republic of Buryatia, as well as samples of Silybum marianum fruits received for analysis at the Testing Center of FGBNU VILAR from different regions of the Russian Federation.
Results. As a result of the research it was found that climatic and geographical conditions of the dry-steppe zone of the Republic of Buryatia allow successful cultivation of Silybum marianum and obtaining raw materials (fruits) of pharmacopoeial quality.
Conclusion. Silybum marianum fruits obtained from plants of the Start variety are not inferior to similar raw materials harvested in other regions of the Russian Federation in the content of the sum of flavolignans.
Keywords
Full Text
About the authors
O. L. Saybel
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants
Author for correspondence.
Email: saybel@vilarnii.ru
Dr.Sc. (Pharm.), Head of the Center of Chemistry and Pharmaceutical Technology
Russian Federation, MoscowE. A. Konyaeva
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants
Email: lencon64@mail.ru
Senior Research Scientist, Department of Chemistry of Natural Compounds
Russian Federation, MoscowO. Y. Kulyak
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants
Email: kulyak-olesya@mail.ru
Ph.D. (Pharm.), Head of Testing Center
Russian Federation, MoscowV. N. Dul
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants
Email: dvnslava@yandex.ru
Ph.D. (Pharm.), Leading Research Scientist, Department of Chemistry of Natural Compounds
Russian Federation, MoscowO. M. Tsybikova
Buryat State Agricultural Academy named after V.R. Filippov
Email: oyuna_sodnom@rambler.ru
Ph.D. (Agricul.), Associate Professor, Department of Plant, Meadow and Horticulture
Russian Federation, Ulan-UdeB. D. Tsydypov
Buryat State Agricultural Academy named after V.R. Filippov
Email: saybel@vilarnii.ru
Senior Lecturer, Department of Plant, Meadow and Horticulture
Russian Federation, Ulan-UdeReferences
- Vichkanova S.A., Kolhir V.K., Sokolskaja T.A., i dr. Lekarstvennye sredstva iz rastenij (Opyt VILAR): nauchnoe izdanie. M.: Adris, 2009. S. 305–315.
- Государственный реестр лекарственных средств РФ. Режим доступа: https://grls.rosminzdrav.ru/grls.aspx (Дата обращения 13.12.2023).
- Zhang X., Jiang Y., Guo N., et al. Application of SNAP-tag-EGFR cell membrane chromatography model in screening antitumor active components of Silybum marianum (L.) Gaertn. J Pharm Biomed Anal. 2024 Jan 20; 238: 115816. doi: 10.1016/j.jpba.2023.115816.
- Gheybi F., Rajabian F., Tayarani-Najaran Z., et al. Liposomal silymarin anti-oxidative and anti-apoptotic features in lung cells: An implication in cadmium toxicity. J Trace Elem Med Biol. 2023 Dec; 80: 127291. doi: 10.1016/j.jtemb.2023.127291.
- Awla N.J., Naqishbandi A.M., Baqi Y. Preventive and Therapeutic Effects of Silybum marianum Seed Extract Rich in Silydianin and Silychristin in a Rat Model of Metabolic Syndrome. ACS Pharmacol Transl Sci. 2023 Oct 27; 6(11): 1715–1723. doi: 10.1021/acsptsci.3c00171.
- Kshnikatkin S.A., Alenin P.G., Voronova I.A. i dr. Jekologicheski bezopasnaja tehnologija vozdelyvanija rastoropshi pjatnistoj. Niva Povolzh'ja. 2021; 3(60): 60–64.
- Najda N.M. Biojekologicheskie osobennosti Silybum marianum v uslovijah leningradskoj oblasti. Izvestija Sankt-Peterburgskogo gosudarstvennogo agrarnogo universiteta. 2022. 4(69): 9–20. doi: 10.24412/2078-1318-2022-4-9-20.
- Kislicyna A.P., Popov F.A., Bobchihin O.V. i dr. Opyt vozdelyvanija rastoropshi pjatnistoj v Kirovskoj oblasti. Biodiagnostika sostojanija prirodnyh i prirodno-tehnogennyh sistem: Materialy HX Vserossijskoj nauchno-prakticheskoj konferencii s mezhdunarodnym uchastiem, Kirov, 01 dekabrja 2022 goda. Kirov: Vjatskij gosudarstvennyj universitet. 2022. S. 346–350.
Supplementary files
