A NEW METHOD OF TINCTURE PREPARATION ON THE BASE OF ARTEMISIAE JACUTICAE HERBA
- Authors: Dylenova E.P1,2, Randalova T.E2, Zhigzhitzhapova S.V1, Radnaeva L.D1,2
-
Affiliations:
- Baikal Institute of Nature Management SB RAS
- Banzarov Buryat State University
- Issue: Vol 22, No 8 (2019)
- Pages: 39-43
- Section: Articles
- URL: https://journals.eco-vector.com/1560-9596/article/view/112667
- DOI: https://doi.org/10.29296/25877313-2019-08-07
- ID: 112667
Cite item
Open Access
Access granted
Abstract
The aim of the research was to develop a new method of tincture preparation from the closely related species of Artemisia absinthium L. - Artemisia jacutica Drob. The object of the study was Artemisiae jacuticae herba collected in Eravninsky region (Buryatia) in 2018 in a flowering stage. The quality of tincture was evaluated by the sum of extractives and the sum of flavonoids referred to determined using UV-spectrophotometry. Extraction on an orbital shaker significantly increases the duration and efficiency of extraction. During the analysis we found that the optimal extractant is 50% ethanol that produces 32,14% of extractives and 0.53% of flavonoids. The best yield of extractives was found during extraction of 0.5 mm raw material, and was 30,29%, and the amount of flavonoids - 0.38%. According to the results, the optimal ration was 1:5 (33,25% of extractives and 0,59% - flavonoids). It was found that the optimal extraction time is 60 minutes, two times. More than that, we obtained tinctures using maceration method lasting from 1 to 7 days. It was revealed that the maximum yield of extractive substances was observed on the 7th day (29.19% - extractives, 0.32% - flavonoids). Thus, we have set the optimal terms of tincture preparation from A. jacuticae herba for the better extractives' efficiency, that included the type of extractant, raw materials' fineness, the ratio of raw material: extractant and duration of extraction.
Keywords
Full Text
About the authors
E. P Dylenova
Baikal Institute of Nature Management SB RAS; Banzarov Buryat State University
Email: edylenova@mail.ru
Post-Graduate Student Ulan-Ude, Russia
T. E Randalova
Banzarov Buryat State UniversityPh.D. (Pharm.) Ulan-Ude, Russia
S. V Zhigzhitzhapova
Baikal Institute of Nature Management SB RASPh.D. (Biol.) Ulan-Ude, Russia
L. D Radnaeva
Baikal Institute of Nature Management SB RAS; Banzarov Buryat State UniversityDr.Sc. (Chem.), Professor Ulan-Ude, Russia
References
- Березовская Т.П., Амельченко В.П., Красноборов И.М., Серых Е.А. Полыни Сибири: систематика, экология, химия, хемосистематика, перспективы использования. Новосибирск: Наука. Сиб. отд-ние, 1991. 125 с.
- Randalova T.E., Sakenova P.Y., Atazhanova G.A., Zhigzhitzhapova S.V., Radnaeva L.D., Adekenov S.M. Comparative analysis of chemical composition of plants of the genus Artemisia containing arglabin of Russian (Buryatia) and Khazakhstan floras // Int. Scientific and Practice Conf. “Achievements and prospects for the development of phytochemistry”. Karaganda, 2015; Czech Chem. Soc. Symp. Ser. 13: 169-173.
- Ханина М.А., Серых Е.А., Амельченко В.П., Покровский Л.М., Ткачев А.В. Результаты интродукционного исследования полыни якутской Artemisia jacutica Drob. // Химия растительного сырья. 1999. № 3. С. 63-78.
- Zhigzhitzhpova S.V., Randalova T.E., Radnaeva L.D., Anenkhonov O.A., Chen Sh.L., Gao Q., Zhang F.Q. Comparative studies on Composition of essential oil in three wormwoods (Artemisia L.) from Buryatia and Mongolia // Journal of Essential oil bearing plants. 2015. V. 18. № 3. Р. 637-641.
- Сальникова Е.Н., Калинкина Г.И., Дмитрук С.Е. Химическое исследование флавоноидов полыни горькой (Artemisia absinthium L.), п. Сиверса (A. Sieversiana Willd.) и п. якутской (A. jacutica Drob.) // Химия растительного сырья. 2001. № 3. С. 71-78.
- Таран Д.Д., Саратиков А.С., Прищеп Т.П. Ранозаживляющие свойства эфирных масел тыcячелистника азиатского и некоторых видов полыни // Военно-медицинский журнал. 1989. № 8. С. 50-52.
- Государственная фармакопея Российской Федерации XIV изд. Т.П. ОФС.1.4.1.0019.15 Настойки. 2018.
- Государственная фармакопея Российской Федерации XIV изд. Т.П. ОФС.1.5.3.0006.15 Определение содержания экстрактивных веществ в лекарственном растительном сырье и лекарственных растительных препаратах. 2018.
- Николаева Г.Г. Настойки, экстракты. Улан-Удэ: Изд-во Бурятского госуниверситета, 2017. 116 с.
Supplementary files
