Pharmacotherapeutic potential of plants of the genus Potentilla

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This review presents data on plants of the genus Potentilla. Some representatives of this genus, features of their distribution, as well as qualitative and quantitative composition are described. Scientific literature data on the pharmacological activity of plants of the genus Potentilla are presented. It has been noted that plants of the genus Potentilla contain amino acids, flavonoids, carbohydrates, saponins, tannins, fatty acids, polysaccharides, macro- and microelements, etc. It has been shown that extracts based on plants of the genus Potentilla exhibit a wide range of effects: antiulcer, antioxidant, antimicrobial, anti-inflammatory, wound healing, immunostimulating, etc. The information presented in the review demonstrates that to date, plants of the genus Potentilla have been studied fragmentarily; among the representatives of the genus, most species are unstudied. The most studied, both in Russia and abroad, are P. alba, P. erecta, P. recta and P. anserina, which provides prerequisites for a more detailed study of the chemical composition of other species of the genus Potentilla and requires additional research into the pharmacological action of extraction preparations based on them. Thus, the available scientific literature data proving the rich phytochemical composition and wide range of effects of plants of the genus Potentilla argue for the prospects of their further study and the creation on their basis of medicinal and parapharmaceuticals for modern medicine and pharmacy, as well as the use of cinquefoil species in the pharmaceutical and food industries.

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作者简介

M. Sergalieva

Astrakhan State Medical University of Minzdrav of Russia

编辑信件的主要联系方式.
Email: charlina_astr@mail.ru
ORCID iD: 0000-0002-9630-2913

Ph.D. in Biology, Associate Professor of the Department of Pharmacognosy, Pharmaceutical Technology and Biotechnology

俄罗斯联邦, 121 Bakinskaya St., Astrakhan, 414000

V. Murtalieva

Astrakhan State Medical University of Minzdrav of Russia

Email: murtalieva90@mail.ru
ORCID iD: 0000-0003-0860-4952

Assistant of the Department of Pharmacognosy, Pharmaceutical Technology and Biotechnology

俄罗斯联邦, 121 Bakinskaya St., Astrakhan, 414000

M. Samotrueva

Astrakhan State Medical University of Minzdrav of Russia

Email: ms1506@mail.ru
ORCID iD: 0000-0001-5336-4455

Dr.Sc. (Med.), Professor, Head of the Department of Pharmacognosy, Pharmaceutical Technology and Biotechnology

俄罗斯联邦, 121 Bakinskaya St., Astrakhan, 414000

参考

  1. Конакова А.В., Кушакова К.А. Перспективы использования фитопрепаратов. Аллея науки. 2019;1(9): 194–196. [Konakova A.V., Kushakova K.A. Prospects for the use of herbal medicines. Alleya nauki. 2019;1(9):194–196. (In Russ.)].
  2. Валли Л.А. Перспективы использования лекарственных растений в современной России. Вестник науки. 2021;1(9): 22–24. [Valli L.A. Prospects for the use of medicinal plants in modern Russia. Vestnik nauki. 2021;1(9):22–24. (In Russ.)].
  3. Самбукова Т.В., Овчинников Б.В., Ганапольский В.П. и др. Перспективы использования фитопрепаратов в современной фармакологии. Обзоры по клинической фармакологии и лекарственной терапии. 2017; 15(2): 55–62. [Sambukova T.V., Ovchinnikov B.V., Ganapol'skii V.P. i dr. Prospects for the use of herbal medicines in modern pharmacology. Obzory po klinicheskoi farmakologii i lekarstvennoi terapii. 2017; 15(2): 55–62. (In Russ.)]. doi: 10.17816/RCF15256-63.
  4. Kumari S., Seth A., Sharma S. et al. A holistic overview of differ-ent species of Potentilla a medicinally important plant along with their pharmaceutical significance: A review. Journal of Herbal Medicine. 2021; 29: 100460. doi: 10.1016/j.hermed.2021.100460.
  5. Мешков И.И., Ториков В.Е., Мешков А.И. Лапчатка белая (Po-tentilla alba L.) – ценное лекарственное сырье. Нива Поволжья. 2021;2(59): 83–90. [Meshkov I.I., Torikov V.E., Meshkov A.I. White cinquefoil (Potentilla alba L.) is a valuable medicinal raw material. Niva Povolzh'ya. 2021; 2(59): 83–90. (In Russ.)]. doi: 10.36461/NP.2021.59.2.014.
  6. Кароматов И.Д., Мавлонов С.С. Лекарственное растение – лапчатка гусиная, ползучая. Биология и интегративная медицина. 2017;2: 228–236. [Karomatov I.D., Mavlonov S.S. Medici-nal plant – creeping cinquefoil. Biologiya i integrativnaya meditsina. 2017; 2: 228–236. (In Russ.)].
  7. Моторыкина Т.Н. Распределение лапчаток (Potentilla L., rosaceae) по бассейновым районам Приамурья и Приморья: статистический анализ данных. Региональные проблемы. 2019; 22(4): 30–36. [Motorykina T.N. Distribution of cinquefoils (Poten-tilla L., rosaceae) across the basin areas of the Amur and Primorye regions: statistical analysis of data. Regional'nye problemy. 2019; 22(4): 30–36. (In Russ.)]. doi: 10.31433/2618-9593-2019-22-4-30-36.
  8. Guo T., Qing Wei J., Ping Ma J. Antitussive and expectorant activities of Potentilla anserine – Pharmaceutical biology. 2016; 54(5): 807–811. doi: 10.3109/13880209.2015.1080734.
  9. Wölfle U., Hoffmann J., Haarhaus B. et al. Antiinflammatory and vasoconstrictive properties of Potentilla erecta – A traditional medicinal plant from the northern hemisphere. Journal of ethnophar-macology. 2017; 204: 86–94. doi: 10.1016/j.jep.2017.03.058.
  10. Augustynowicz D., Latté K.P., Tomczyk M. Recent phytochemical and pharmacological advances in the genus Potentilla L. sensu lato – An update covering the period from 2009 to 2020. Journal of Ethnopharmacology. 2021; 266: 113412. doi: 10.1016/j.jep.2020.113412.
  11. Князева Г.Е., Пашков А.Н., Карташова Н.М. и др. Действующие вещества в некоторых видах рода Лапчатка (Potentilla L.). Метод Z. 2022;3(5):9–11. [Knyazeva G.E., Pashkov A.N., Kartashova N.M. i dr. Active ingredients in some species of the genus Potentilla L. Metod Z. 2022; 3(5): 9–11. (In Russ.)].
  12. Досаева А.Н. Химический профиль отдельных видов лапчатки. Новое слово в науке: стратегии развития. 2022; 10–11. [Dosaeva A.N. Chemical profile of selected cinquefoil species. Novoe slovo v nauke: strategii razvitiya. 2022; 10–11. (In Russ.)].
  13. Fecka I., Kucharska A.Z., Kowalczyk A. Quantification of tannins and related polyphenols in commercial products of tormentil (Potentilla tormentilla). Phytochemical analysis. 2015; 26(5): 353–366. doi: 10.1002/pca.2570.
  14. Бубенчикова В.Н., Сухомлинов Ю.А. Изучение состава фенольных соединений лапчатки прямостоячей методом ВЭЖХ. Вестник ВГУ. Серия: Химия. Биология. Фармация. 2005; 2: 160–161. [Bubenchikova V.N., Sukhomlinov Yu.A. Study of the composition of phenolic compounds in Potentilla erecta using HPLC. Vestnik VGU. Seriya: Khimiya. Biologiya. Farmatsiya. 2005; 2:160–161. (In Russ.)].
  15. Копытько Я.Ф. Летучие вещества спиртового извлечения из корневища Лапчатки прямостоячей (Potentilla erecta (L.) Rausch). Перспективы лекарственного растениеведения. 2018; 466–473. [Kopyt'ko Ya.F. Volatile substances of alcoholic extract from the rhizome of Potentilla erecta (L.) Rausch. Perspektivy le-karstvennogo rastenievedeniya. 2018; 466–473. (In Russ.)].
  16. Семенова Е.Ф., Преснякова Е.В. Химический состав лапчатки белой и применение ее с лечебной целью. Химия и компьютерное моделирование. Бутлеровские сообщения. 2001; 5: 13–19. [Semenova E.F., Presnyakova E.V. The chemical composition of white cinquefoil and its use for medicinal purposes. Khimiya i komp'yuternoe modelirovanie. Butlerovskie soobshcheniya. 2001; 5: 13–19. (In Russ.)].
  17. Богачева Н.Г., Мешков А.И., Коняева Е.А. и др. Фармакогностическое изучение корневищ и корней лапчатки белой (Potentilla alba L.). Вопросы биологической, медицинской и фармацевтической химии. 2016; 19(1): 28–32. [Bogacheva N.G., Meshkov A.I., Konyaeva E.A. i dr. Pharmacognostic study of rhizomes and roots of white cinquefoil (Potentilla alba L.). Voprosy biologicheskoi, meditsinskoi i farmatsevticheskoi khimii. 2016; 19(1): 2832. (In Russ.)].
  18. Осипов В.И., Поляков Н.А., Сидельников А.Н. и др. Протоантоцианидины корней и корневищ Potentilla alba L. (Rosaceae). «Растительные ресурсы». 2017; 53(1): 114–125. [Osipov V.I., Polyakov N.A., Sidel'nikov A.N. i dr. Protoanthocyanidins of the roots and rhizomes of Potentilla alba L. (Rosaceae). «Rastitel'nye resursy». 2017; 53(1): 114–125. (In Russ.)].
  19. Базарнова Н.Г., Тихомирова Л.И., Фролова Н.С. и др. Выделение и анализ экстрактивных веществ лапчатки белой (Potentilla alba L.), выращенной в разных условиях. Химия растительного сырья. 2016; 1: 43–51. [Bazarnova N.G., Tikhomirova L.I., Frolova N.S. i dr. Isolation and analysis of extractive substances from white cinquefoil (Potentilla alba L.) grown under different conditions. Khimiya rastitel'nogo syr'ya. 2016; 1: 43-51. (In Russ.)]. doi: 10.14258/jcprm.201601933.
  20. Абрамчук А.В., Карпухин М.Ю. Особенности применения лапчатки (Potentilla L.) в медицине. Вестник биотехнологии. 2019; 3: 15–15. [Abramchuk A.V., Karpukhin M.Yu. Features of the use of cinquefoil (Potentilla L.) in medicine. Vestnik biotekhnologii. 2019; 3: 15–15. (In Russ.)].
  21. Luo Z., Wang S., Wang D. Phenolic profiles and antioxidant capacities of crude extracts and subsequent fractions from Potentilla fruticosa L. leaves. Natural Product Research. 2016; 30(16): 1890–1895. doi: 10.1080/14786419.2015. 1084303.
  22. Yu D., Pu W., Li D. et al. Phenolic compounds and antioxidant activity of different organs of Potentilla fruticosa L. from two main production areas of China. Chemistry & Biodiversity. 2016;13(9):1140–1148. doi: 10.1002/cbdv.201500512.
  23. Uysal S., Zengin G., Mahomoodally M.F. et al. Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species. South African journal of botany. 2019; 120: 124–128. doi: 10.1016/j.sajb.2018.01.014.
  24. Tomczyk M., Latté K.P. Potentilla – A review of its phytochemical and pharmacological profile. Journal of ethnopharmacology. 2009; 122(2): 184–204. doi: 10.1016/j.jep.2008.12.022.
  25. Хисямова Д.М., Куркин В.А., Лямин А.В. и др. Антимикробная активность водных извлечений из подземных органов некоторых видов лапчатки. Фармация. 2016; 65(1): 32–34. [Khisyamova D.M., Kurkin V.A., Lyamin A.V. i dr. Antimicrobial activity of aqueous extracts from underground organs of some cinquefoil species. Farmatsiya. 2016; 65(1): 32–34. (In Russ.)].
  26. Hoffmann J., Casetti F., Bullerkotte U. et al. Anti-inflammatory effects of agrimoniin-enriched fractions of Potentilla erecta. Molecules. 2016;21(6):792. doi: 10.3390/molecules21060792.
  27. Paduch R., Wiater A., Locatelli M. et al. Aqueous extracts of selected Potentilla species modulate biological activity of human normal colon cells. Current Drug Targets. 2015; 16(13): 1495–1502.
  28. Tunon H., Olavsdotter C., Bohlin L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. Journal of Ethnopharmacology. 1995; 48(2): 61–76. doi: 10.1016/0378-8741(95)01285-L.
  29. Захарченко А.В., Базарнова Н.Г., Ильичева Т.Н. и др. Влияние экстрактивных веществ лапчатки белой и кровохлебки лекарственной на сенную палочку и сальмонеллу. В сборнике: От биопродуктов к биоэкономике. Материалы IV Межрегиональной научно-практической конференции (с международным участием). Барнаул, 2021; 276–278. [Zakharchenko A.V., Bazarnova N.G., Il'icheva T.N. i dr. The effect of extractive substances from Potentilla white and Burnet officinalis on Bacillus subtilis and Sal-monella. V sbornike: Ot bioproduktov k bioekonomike. Materialy IV Mezhregional'noi nauchno-prakticheskoi konferentsii (s mezhdunarodnym uchastiem). Barnaul. 2021; 276–278. (In Russ.)].
  30. Wang S.S., Wang D.M., Pu W.J. et al. Phytochemical profiles, antioxidant and antimicrobial activities of three Potentilla species. BMC Complementary and alternative medicine. 2013; 13(1): 1–11.
  31. Tosun A., Bahadir Ö., Altanlar N. Antimicrobial activity of some plants used in folk medicine in Turkey. Turk J Pharm Sci. 2006; 3(3): 167–176.
  32. Evstropov A.N., Burova L.G., Grek O.R. et al. Experimental thera-py of Coxsackie B3 virus infection with immunomodulator con-tained in water-soluble Penthaphylloides fruticosa extract. Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii. 2005;3:102–104.
  33. Zhao Y.L., Cai G.M., Hong X. et al. Anti-hepatitis B virus activities of triterpenoid saponin compound from Potentilla anserine L. Phy-tomedicine. 2008; 15(4): 253–258.
  34. Смык Г.К. Лапчатка белая – эффективное средство для лечения заболеваний щитовидной железы. Фармацевтический журнал. 1975; 2: 58–62. [Smyk G.K. White cinquefoil is an effective remedy for the treatment of thyroid diseases. Farmatsevticheskii zhurnal. 1975; 2: 58–62. (In Russ.)].
  35. Водопьянова А.М., Архипова Э.В., Шантанова Л.Н. и др. Лапчатка белая как перспективное средство для лечения заболеваний щитовидной железы. Acta Biomedica Scientifica. 2011; 12: 131–134. [Vodop'yanova A.M., Arkhipova E.V., Shantanova L.N. i dr. White cinquefoil as a promising remedy for the treatment of thyroid diseases. Acta Biomedica Scientifica. 2011; 12: 131–134. (In Russ.)].
  36. Архипова Э.В., Водопьянова А.М., Колхир В.К. Влияние экс-тракта сухого лапчатки белой на течение экспериментального гипотиреоза. Acta Biomedica Scientifica. 2011; 12: 116–118. [Arkhipova E.V., Vodop'yanova A.M., Kolkhir V.K. Effect of dry cinquefoil extract on the course of experimental hypothyroidism. Acta Biomedica Scientifica. 2011; 12: 116–118. (In Russ.)].
  37. Pankiv V.I. New possibilities of phytotherapy for hypothyroidism. International journal of endocrinology. 2020; 16(2): 152–155.
  38. Каминский А.В., Киселёва И.А., Тёплая Е.В. Клинические возможности применения лапчатки белой в профилактике и лечении патологии щитовидной железы. Эндокринология. 2014; 1: 45–50. [Kaminskii A.V., Kiseleva I.A., Teplaya E.V. Clinical possibilities of using white cinquefoil in the prevention and treatment of thyroid pathology. Endokrinologiya. 2014; 1: 45–50. (In Russ.)].
  39. Min G.T. Protective mechanism of Potentilla anserina polysaccharide on mice with D-galactosamine-induced acute liver injury. Aca-demic Journal of Second Military Medical University. 2016; 916–919.
  40. Kolpakov M.A., Grek O.R., Bashkirova Y.V. et al. Hepatoprotective properties of aqueous extract from Pentaphylloides fruticosa during chronic toxic hepatitis. Bulletin of Experimental Biology and Medi-cine. 2001; 131: 470–472.
  41. Qin X.J., Li L.Z., Qi L.V. et al. Neuroprotection of n-Butanol ex-tract from roots of Potentilla anserina on hypoxic injury in primary hippocampal neurons – Chinese herbal medicines. 2012; 4(3): 195–200. doi: 10.3969/j.issn.1674-6384.2012.03.004.
  42. Youngken H.W., Neva A.C., Dauben H.J. et al. The muscle relaxant effects produced by Potentilla anserina extracts. I. Fractionation studies. Journal of Pharmaceutical Sciences. 1949; 38(8): 448–451. doi: 10.1002/jps.3030380809.
  43. Laloo D., Prasad S.K., Krishnamurthy S. et al. Gastroprotective activity of ethanolic root extract of Potentilla fulgens Wall. ex Hook. Journal of ethnopharmacology. 2013; 146(2): 505–514. doi: 10.1016/j.jep.2013.01.015.
  44. Anheyer D., Frawley J., Koch A.K. et al. Herbal medicines for gas-trointestinal disorders in children and adolescents: a systematic review. Pediatrics. 2017; 139(6): 20170062. doi: 10.1542/peds.2017-0062.
  45. Хобракова В.Б., Архипова Э.В. Иммунокорригирующее действие сухого экстракта лапчатки белой и комплексного средства «Тиреотон». Сибирский медицинский журнал. 2011; 106(7): 121–123. [Khobrakova V.B., Arkhipova E.V. Immunocorrective effect of dry extract of white cinquefoil and the complex product “Thyreoton”. Sibirskii meditsinskii zhurnal. 2011; 106(7): 121–123. (In Russ.)].
  46. Токешова Л.Е. Лекарственные растения и их препараты, используемые в качестве иммуномодуляторов. Materials of the II International Conference “Natural Products: Chemistry, Technology and Medicinal Perspectives”. Алматы. 2007; 161. [Tokeshova L.E. Medicinal plants and their preparations used as immunomodulators. Materials of the II International Conference “Natural Products: Chemistry, Tech-nology and Medicinal Perspectives”. Almaty. 2007; 161. (In Russ.)].
  47. Бортникова В.В., Крепкова Л.В., Мизина П.Г. и др. Исследования иммунотоксических и аллергизирующих свойств лапчатки белой (Potentilla Alba L.) экстракта сухого. Токсикологический вестник. 2018; 4(151): 15–19. [Bortnikova V.V., Krepko-va L.V., Mizina P.G. i dr. Studies of the immunotoxic and allergenic properties of white cinquefoil (Potentilla Alba L.) dry extract. Toksikologicheskii vestnik. 2018; 4(151): 15–19. (In Russ.)].
  48. Radovanovic A.M., Cupara S.M., Popovic S.Lj. et al. Cytotoxic effect of Potentilla reptans L. rhizome and aerial part extracts. Acta Pol. Pharm. 2013;70(5):851–854.
  49. Spiridonov N.A., Arkhipov V.V., Konovalov D.A. Cytotoxicity of some Russian ethnomedicinal plants and plant compounds. Phytotherapy research. 2005; 19(5): 428–432. doi: 10.1002/ptr.1616.
  50. Anal J.M.H., Majeed R., Bez G. et al. In vitro cytotoxicity of the polar extracts of Potentilla fulgens L. against human cancer cell lines: Detection and isolation of bioactive phenolics. Journal of chemical and pharmaceutical research. 2014; 6(9): 89–95.
  51. Jin Q., Nan J.X., Lian L.H. Antitumor activity of leaves from Potentilla discolor on human hepatocellular carcinoma cell line HepG-2. Chinese journal of natural medicines. 2011;9(1):61–64. doi: 10.1016/S1875-5364(11)60022-8.
  52. Zhang J., Liu C., Huang R.Z. et al. Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities. PloS One. 2017; 12(4): 1–18. doi: 10.1371/journal.pone.0175502.
  53. Yu H.J., Ahn C.H., Yang I.H. et al. Apoptosis induced by methanol extract of Potentilla discolor in human mucoepidermoid carcinoma cells through STAT3/PUMA signaling axis. Molecular Medicine Reports. 2018; 17(4): 5258–5264. doi: 10.3892/mmr.2018.8468.
  54. Kowalik K., Paduch R., Strawa J.W. et al. Potentilla alba extracts affect the viability and proliferation of non-cancerous and cancerous colon human epithelial cells. Molecules. 2020; 25(13): 3080. doi: 10.3390/molecules25133080.
  55. Enomoto S., Okada Y., Güvenc A. et al. Inhibitory effects of tradi-tional Turkish folk medicine on aldose reductase (AR) and hemato-logical activity, and on AR inhibitory activity of quercetin-3-Omethyl ether isolated from Cistus laurifolius L. Biological and Pharmaceutical Bulletin 2004; 27(7): 1140–1143. doi: 10.1248/bpb.27.1140.
  56. Qiao W., Zhao C., Qin N. et al. Identification of transtiliroside as active principle with anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects from Potentilla chinensis. Journal of ethnophar-macology. 2011; 135(2): 515–521. doi: 10.1016/j.jep.2011.03.062.
  57. Лежнева Л.П., Темирбулатова А.М., Степанова Э.Ф. и др. Динамика ранозаживления при лечении мазью с сухим экстрактом лапчатки. Кубанский научный медицинский вестник. 2018; 25(6): 105–109. [Lezhneva L.P., Temirbulatova A.M., Stepanova E.F. i dr. Dynamics of wound healing when treated with ointment with dry extract of cinquefoil. Kubanskii nauchnyi med-itsinskii vestnik. 2018; 25(6): 105–109. (In Russ.)]. doi: 10.25207/1608-6228-2018-25-6-105-109.
  58. Kundu A., Ghosh A., Singh N.K. et al. Wound healing activity of the ethanol root extract and polyphenolic rich fraction from Potentilla fulgens. Pharmaceutical biology. 2016; 54(11): 2383–2393. doi: 10.3109/13880209.2016.1157192.
  59. Shikov A.N., Lazukina M.A., Pozharitskaya O.N. et al. Pharmaco-logical evaluation of Potentilla alba L. in mice: adaptogenic and central nervous system effects. Pharmaceutical Biology. 2011; 49(10): 1023–1028. doi: 10.3109/13880209.2011.560162.
  60. Syiem D., Syngai C., Khup P.Z. et al. Hypoglycemic effects of Po-tentilla fulgens L. in normal and alloxan-induced diabetic mice. Journal of Ethnopharmacology. 2002; 83(12): 55–61. doi: 10.1016/S0378-8741(02)00190-3.
  61. Хобракова В.Б., Архипова Э.В., Водопьянова А.М. Влияние сухого экстракта лапчатки белой на состояние клеточного и гуморального звеньев иммунного ответа. Бюллетень ВСНЦ СО РАМН. 2011; 1(77): 195–197. [Khobrakova V.B., Arkhipova E.V., Vodop'yanova A.M. The influence of dry extract of white cinquefoil on the state of the cellular and humoral components of the immune response. Byulleten' VSNTs SO RAMN. 2011; 1(77): 195–197. (In Russ.)].
  62. Киселева И.А., Теплая Е.В., Каминский А.В. Применение растительного препарата «Альба®» в лечении больных с патологией щитовидной железы. Врачебное дело. 2012; 8: 116–119. [Kiseleva I.A., Teplaya E.V., Kaminskii A.V. The use of the herbal preparation "Alba®" in the treatment of patients with thyroid pathology. Vrachebnoe delo. 2012; 8: 116–119. (In Russ.)].

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