Safety in parathyroid surgery: innovation in diagnostic and minimally invasive operations

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Abstract

The main treatment method of primary and tertiary hyperparathyroidism is surgery. However, surgical interventions on the parathyroid glands can lead to formidable complications such as laryngeal paresis and hypocalcemia. With this background, a comprehensive study examined the effectiveness of modern methods of diagnosis and surgical treatment of hyperparathyroidism to increase the safety level in surgery of the thyroid gland. The results of a comprehensive examination and treatment of 53 patients with hyperparathyroidism who underwent surgery using three methods were analyzed: traditional (n = 18/34); minimally invasive endoscopically assisted (n = 32/60), and endoscopic (transoral) (n = 3/6). Intraoperative neuromonitoring was also performed in all surgical interventions. Parathyroidectomy was performed under parathyroid monitoring for intraoperative topical diagnosis of parathyroid tumors in nine patients. The use of minimally invasive endoscopically assisted access to the parathyroid glands, as an alternative to the traditional approach, indicated that the preoperative potential in the diagnosis of parathyroid disorders. Moreover, intraoperative neuromonitoring and parathyroid monitoring demonstrated efficiency based on the decline in the incidence of specific postoperative complications with a tolerable increase in operative time, maintenance of the average duration of stationary treatment after surgery, and increased safety level of surgical treatment of hyperparathyroidism.

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About the authors

Pavel N. Romashchenko

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: romashchenko@rambler.ru
ORCID iD: 0000-0001-8918-1730
SPIN-code: 3850-1792

doctor of medical sciences, professor

Russian Federation, Saint Petersburg

Nikolaj A. Maistrenko

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: nik.m.47@mail.ru
ORCID iD: 0000-0002-1405-7660
SPIN-code: 2571-9603

doctor of medical sciences, professor

Russian Federation, Saint Petersburg

Dmitry O. Vshivtsev

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: dvo_vsh@mail.ru
ORCID iD: 0000-0002-9000-427X
SPIN-code: 9087-2432

senior resident

Russian Federation, Saint Petersburg

Denis S. Krivolapov

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: d.s.krivolapov@yandex.ru
ORCID iD: 0000-0002-9499-2164
SPIN-code: 2195-5001

senior resident

Russian Federation, Saint Petersburg

Andrey S. Pryadko

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation; Leningrad Regional Clinical Hospital

Author for correspondence.
Email: pradko66@mail.ru
ORCID iD: 0000-0002-7848-6704
SPIN-code: 2684-3990

head of the surgical department

Russian Federation, Saint Petersburg; Saint Petersburg

References

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  3. Romashchenko PN, Maistrenko NA, Krivolapov DS, et al. New standard of conclusiveness and safety in the parathyroid surgery. Grekov’s Bulletin of Surgery. 2020;179(1):58–62. (In Russ.) doi: 10.24884/0042-4625-2020-179-1-58-62
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  10. Romashchenko PN, Maistrenko NA, Krivolapov DS, et al. The radio navigation and photodynamic methods of parathyroid glands’ intraoperative visualisation (review of the literature). Grekov’s Bulletin of Surgery. 2020;179(3):113–119. (In Russ.). doi: 10.24884/0042-4625-2020-179-3-113-119
  11. De Leeuw F, Breuskin I, Abbaci M, et al. Intraoperative near-infrared imaging for parathyroid gland identification by autofluorescence: a feasibility study. World J Surg. 2016;40(9):2131–2138. doi: 10.1007/s00268-016-3571-5
  12. Chernykh AV, Maleev YuV, Shevtsov AN, et al. The prediction model features the topography of the parathyroid glands with the use of regression analysis. Tavricheskiy Mediko-Biologicheskiy Vestnik. 2017;20(3):273–280. (In Russ.).

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Copyright (c) 2021 Romashchenko P.N., Maistrenko N.A., Vshivtsev D.O., Krivolapov D.S., Pryadko A.S.

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