Relationship of creativity and genetic factors in military services in the conditions of the arctic region
- Authors: Spivak I.M.1, Lemeshchenko A.V.1, Agafonov P.V.1, Khalimov Y.S.1, Zhekalov A.N.1, Gaiduk S.V.1, Spivak D.L.2
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Affiliations:
- Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
- N.P. Bekhtereva Institute of the Human Brain
- Issue: Vol 23, No 4 (2021)
- Pages: 139-146
- Section: Clinical Trials
- URL: https://journals.eco-vector.com/1682-7392/article/view/84997
- DOI: https://doi.org/10.17816/brmma84997
- ID: 84997
Cite item
Abstract
The article examines the relationship between the creativity and genetic factors in a serviceman serving in the Arctic region with the special climatic and geographical parameters, a kind of sanitary and epidemiological situation, as well as the complexity of a military labor. A linear correlation analysis of the indicators of a creativity was carried out as one of the most important abilities of the personality, allowing timely response and adaptation to the changing conditions of the external social environment, and the polymorphism of four genes that take an active part in the process of the adaptation to the conditions of the Arctic region: the gene for the serotonin receptor 2A, the gene for angiotensin converting enzyme-1, the gene for neurotrophic factor, as well as the gene for alpha-actinin-3. It was found that the maximum level of verbal and imaginative creativity is observed in carriers of the Val / Val genotype of the neurotrophic factor gene, as well as the RR genotype of the alpha-actinin-3 gene. The carriers of these genotypes are characterized by a high production of neurotrophines that stimulate and support the development of neurons, which may determine the resistance of the central nervous system to unfavorable factors of the external social environment. In addition, the high level of expression of the alpha-actinin-3 protein, characteristic of carriers of the RR genotype of the alpha-actinin-3 gene, promotes accelerated regeneration of skeletal muscles, which may contribute to more optimal adaptation of the body to the harsh conditions of the Arctic region associated with an increased muscle load. When analyzing the angiotensin-converting enzyme gene, the observed patterns with the level of creativity turned out to be less clear, although the servicemen with the DD genotype of this gene showed a minimum level of creativity, which corresponds to the general idea of it as a “weaker” genotype in terms of the level of general body metabolism and the ability to be active. The characteristics of the creativity in genotypes II and ID of the angiotensin converting enzyme gene were statistically uncertain. The good tightness of the correlation of creativity with the Val/Val genotype of the neurotrophic factor gene, as well as the RR genotype of the alpha-actinin-3 gene, may indicate the advisability of including military personnel planned to be sent to the Arctic region in the examination plan to determine the level of creativity. This will optimize the process of selecting servicemen for service in the Arctic region, and prevent the development of maladjustment disorders, excluding persons with a low adaptive potential.
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About the authors
Irina M. Spivak
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: Irina_spivak@hotmail.com
ORCID iD: 0000-0003-1351-8696
SPIN-code: 6740-5392
Scopus Author ID: 7004303441
ResearcherId: F-9059-2015
candidate of biological sciences, associate professor
Russian Federation, Saint PetersburgAlexey V. Lemeshchenko
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: vmeda-nio@mil.ru
ORCID iD: 0000-0001-6786-2332
SPIN-code: 8534-0822
candidate of medical sciences
Russian Federation, Saint PetersburgPavel V. Agafonov
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Author for correspondence.
Email: vmeda-nio@mil.ru
ORCID iD: 0000-0003-4934-320X
SPIN-code: 3303-4786
Scopus Author ID: 57189606691
candidate of medical sciences
Russian Federation, Saint PetersburgYuri S. Khalimov
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: yushkha@gmail.com
ORCID iD: 0000-0002-7755-7275
SPIN-code: 7315-6746
Scopus Author ID: 464335
doctor of medical sciences, professor
Russian Federation, Saint PetersburgAndrey N. Zhekalov
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: vmeda-nio@mil.ru
ORCID iD: 0000-0003-4821-7340
SPIN-code: 3154-9228
Scopus Author ID: 879266
doctor of medical sciences
Russian Federation, Saint PetersburgSergey V. Gaiduk
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: gaiduksergey@mail.ru
SPIN-code: 8602-4922
Scopus Author ID: 884012
doctor of medical sciences, associate professor
Russian Federation, Saint PetersburgDmitry L. Spivak
N.P. Bekhtereva Institute of the Human Brain
Email: info@heritage-institute.ru
ORCID iD: 0000-0001-7276-5182
SPIN-code: 6764-3561
Scopus Author ID: 7003747634
doctor of biological sciences
Russian Federation, Saint PetersburgReferences
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