The adhesive properties of the “Tachocomb” hemostatic plate with prostheses of the brain dura mater

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The adhesion of the Tahokomb hemostatic plate of Takeda (Japan) to the solid cerebral membrane prostheses from materials of various origins was experimentally investigated to determine which of them the implants under study best provide tachocomb fixation and contribute to the prevention of postoperative liquorrhea and infectious complications resulting from leaks in the subdural space. It was found that the greatest adhesion of tachocomb was revealed to xenogenic prostheses having collagen in their composition, which characterizes them as optimal prostheses for plasticizing defects of the solid cerebral membrane from the point of view of sealing the subdural space. Intermediate values were observed in the study of prostheses of combined origin, and the lowest adhesion of tachocomb was observed with respect to synthetic prostheses. Of some interest are new composite substitutes for the hard brain (NeoDura, Medprin), created as a mix of synthetic and organic materials. The surface texture of these solid cerebral membrane analogues approaches collagen implants in characteristics, and is similar to the structure of the native solid cerebral membrane. Based on the data obtained, we can talk about the priority use of solid braincase prostheses based on animal collagen - not only due to the high adhesion parameters of tachocomb to them, but also due to other qualities: resorbability, facilitating the deposition of recipient fibroblast materials on the surface.

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作者简介

Vyacheslav Vinogradov

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

编辑信件的主要联系方式.
Email: ulytreack@gmail.com
ORCID iD: 0000-0001-5930-3805
SPIN 代码: 9629-1818

cadet

俄罗斯联邦, Saint Petersburg

Dmitriy Alekseev

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: dealekseev@mail.ru
ORCID iD: 0000-0002-8685-3965
SPIN 代码: 9823-8976

candidate of medical sciences

俄罗斯联邦, Saint Petersburg

Dmitriy Svistov

Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation

Email: kolba81@yandex.ru
ORCID iD: 0000-0002-3922-9887
SPIN 代码: 3184-5590

candidate of medical sciences, associate professor

俄罗斯联邦, Saint Petersburg

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版权所有 © Vinogradov V.V., Alekseev D.E., Svistov D.V., 2021

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