ALLELIC POLYMORPHISM OF CYTOKINE GENESIN CHRONIC RENAL TRANSPLANT REJECTION
- Authors: Gumilevskiy B.Y.1, Gumilevskaya OP1, Gumilevskiy BY1, Gumilevskaya OP1
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Affiliations:
- Issue: Vol 7, No 3 (2010)
- Pages: 62-65
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118163
- ID: 118163
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Abstract
Polymorphism of promoter region of cytokine genes (IL-1α, IL-1β, IL-1R, IL-1RA, IL-12, IL-2, IL-4, IL-6, IL-8, IL-10, IFN-γ, TNF-α, TGF-β) in 98 recipients of allogenic kidney was studied. It is shown that the development of chronic renal transplant
rejection is associated with the structural features of genes of key cytokines IL-1α, IL-10, TNF-β, receptor of IL-4.
rejection is associated with the structural features of genes of key cytokines IL-1α, IL-10, TNF-β, receptor of IL-4.
Keywords
About the authors
Boris Yur'evich Gumilevskiy
Email: gumbu@mail.ru
O P Gumilevskaya
B Y Gumilevskiy
O P Gumilevskaya
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