Vol 3, No 4 (2006)

The article deals with problems of using the principles of evidence-based medicine in radiology; it discusses the main problems which a doctor faces when searching for the most effective diagnostic method. Primary criteria for evaluating the efficiency of visualization methods and levels of evidence are discussed.

Medical management of rheumatoid arthritis (RA) is aimed at controlling or reducing the inflammatory process in order to prevent or slow down damage to the joint and to maintain or improve the functional status. However, it is well established that inflammation indicators may be stable or improved, whereas radiographic evidence shows that joint damage progresses. A new class of agents termed "biological agents" have been approved for use in RA according to the data of the evidence-based medicine. Until more is known about the long-term safety and efficacy of these drugs, they should be reserved for patients with severe conditions who are progressing despite adequate doses of methotrexate or other DMARD.

122 patients with acute myocardial infarction participated in the study. They received standard therapy and Asparcam-L or Panangin, or potassium and magnesium asparaginate. Efficiency and safety was studied with ECG, echocardiogram, quality of life questionnaires and laboratory methods. Asparcam-L presented good tolerance, safety and efficiency during acute myocardial infarction treatment, as well as a better prognosis.

Peculiarities of chronophysiological rhythms of temperature, electrical and mechanical pain thresholds and two-point discriminative tactile thresholds of oral mucosa were evaluated. Comparative analysis showed a similarity between chronophysiological rhythms of pain perception and tactile sensation from 8 a.m. to 8 p.m. It was established that the extremes of pain and two-point discriminative tactile perception develop from 12 a.m. to 2 p.m., and minimum perception is at 8 a.m. and from 6 p.m. to 8 p.m. Correlations between temperature, electrical and mechanical pain thresholds were revealed, as well as correlations between these types of pain sensations and tactile perception of oral mucosa. These results allow a prediction of individual level of pain sensation during dental treatment.

High frequency of postpartum infectious complications makes them one of the most actual problems in modern obstetrics. Investigation of 186 parturient women with post-parturition infectious complications revealed elevated level of cytokines ((IL-1, IL-6, TNF) and endotoxin in the serum of the patients associated with the changes in the albumin metabolism and neuro-humoral regulation manifested by the changed level of Cortisol and prolactin. Inclusion of trascranial electrostimulation and medication dibicor in the complex treatment showed marked clinical effect and provided fast restoration of physiological level of regulation. The results of the research were evaluated from the positions of the systemic inflammatory response development.

In the article the structural and mechanical features of the the oinment compositions with mineral bishofit on the water-soluble polyethylenglycolic base are evaluated.

In the paper the author analyzes the scientific potential of the research workers defending MrSci and PhD-theses in stomatology in the dissertation council of the VolGMU considering their age and gender characteristics.

Health care reform presupposes its structural reorganization with incorporation into the medical establishment of specialties that are new for domestic medicine: social work and medical psychology. The changes of traditional Russian culture of healing embodied in the image of a perfect zemsky physician are taking the shape of dramatic overwork for practicing physicians, including some functions non-medical in essence and requiring specialist training. Further labour division taking place within the medical speciality expands the whole health care system by means of introducing professions with non-medical educational background, which, however, contribute greatly to the efficacy of medicine and improvement of health and life quality.

Modern antihypertensive medicines have both useful and unfavourable effects on gestation. The article demonstrates efficacy and safety of "Dibicor" in pharmacotherapy of pregnant women with arterial hypertension.

In this study we analyzed the CVH infection epidemiology and efficacy of CVH therapy with "Peginterferon-Alpha 2a" and "Ribavirin". "Pegasys" and "Ribavirin" therapy was more effective than "Roferon" and "Ribavirin" therapy in patients with CHV type 1 in our region. Predictors of efficacy endpoint (CVH RNA reduction) were determined partially.

The article presents the results of application of epidural anaesthesia in pregnant women with gestosis and different degrees of miopia.

In the review devoted to problems of diagnostics and medication treatment of sinusitis, modern view on pathogenesis of sinusitis is presented. Principles of diagnostics and approaches to treatment of sinusitis are discussed.

Factual data on the perception of educational environment as positive, neuter, aggressive compared with the style of communication at the medicobiological departments of VolSMU are reported. The data are indispensable in designing educational environment of the department.