Volgograd Journal of Medical Research

Quarterly, peer-reviewed scientific journal.

Editor-in-Chief

  • Sergey V. Dmitrienko, Doctor of Medical Sciences, Professor, PhD 

Publisher

  • Publishing house of the Volgograd State Medical University

Founders

  • Publishing house of the Volgograd State Medical University

Indexing

  • Russian Science Citation Index (RSCI)
  • Google Scholar

Frequency

  • 4 issues per year

About journal

The "Volgograd Scientific Medical Journal" accepts scientific papers in the form of articles, reflecting the results of completed fundamental and practical scientific research, corresponding to the profile of the journal. The main headings of the scientific publication are: scientific reviews, scientific articles (original studies), scientific reviews, reviews on the following scientific specialties: public health and healthcare organization, sociology and history of medicine, dentistry, internal medicine, surgery, pharmacology, clinical pharmacology, pathological anatomy , human anatomy, hygiene, restorative medicine, sports medicine, exercise therapy, balneology and physiotherapy.

 

Main headings

  • Clinical medicine
  • Health sciences
  • Medical biotechnology
  • Dentistry
  • Pharmacology, clinical pharmacology
  • Public health, organization and sociology of healthcare

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Current Issue

Vol 23, No 1 (2026)

Cover Page

Full Issue

Articles

The role of the institute of tutoring in a surgical clinic
Shkarin V.V., Dronova E.P., Еmelyanova O.S., Myakonky R.V.
Abstract

The relevance of the study is determined by the fact that there is currently insufficient information covering the entire range of stages of training and adaptation of young surgeons in medical organizations using the mentorship institute. Purpose: To develop and justify the implementation of the mentorship institute in surgical departments in order to improve the professional adaptation of young specialists and the quality of surgical care. Material and methods: A prospective comparative study was conducted using the method of random distribution of participants between groups. The study included 232 surgeon doctors working in state medical institutions in Volgograd. The groups were formed taking into account the participation of young surgeon doctors in the mentoring program. The analysis used methods of questioning and interviewing, observation, expert assessment, and testing of the study participants. Results and discussion: The study found that after completing the mentorship program, young doctors in the first group (n = 84) showed a significantly lower level of anxiety (32.1 ± 5.3) compared to the control group (n = 83) (47 ± 5.2), performed more independent surgeries (1 980 vs. 1 766), and worked more effectively as a team. They also used endoscopic methods and telemedicine more actively (1004 consultations and 986 consults vs. 301 and 542). Training in practical surgical skills is accelerated by 33.0 %, the average operation time is reduced by 15 minutes, diagnostic and management errors are reduced by 72.0 %, complications are reduced by 68.0 %, the hospital stay is reduced by 2 days, and patient satisfaction is increased by 13.0 %. Staff turnover is lower by 3.7 %. Conclusion: The conducted study proved the effectiveness of the mentoring program in developing the professional skills of young surgeons. The results of the study can be used by healthcare managers and heads of surgical services in practical activities, when conducting thematic master classes to improve the quality of medical care, in the educational process at the departments of the surgical profile and in the lecture course at the Department of Public Health and Healthcare of the Institute of Continuing Medical and Pharmaceutical Education of VolgSMU.

Volgograd Journal of Medical Research. 2026;23(1):5-12
pages 5-12 views
Goal-setting of state control of quality and safety of medical activities
Starzhinskaya O.В., Shishov M.A.
Abstract

The healthcare management system includes federal government oversight, which has undergone changes over the past quarter century due to the transition to a digital society and the abandonment of the Soviet punitive paradigm. At the same time, modern risk management, as a key element of oversight, faces a lack of theoretical research, which hinders its effective application, especially in the context of the specific healthcare sector. Purpose: Тo study the features of goal-setting of federal state control over the quality and safety of medical activities, to identify its potential goals, priorities and development directions. Materials and methods: The study used analytical and formal-legal methods. Statistical data on the total number of regulatory requirements and specialized legal documents in the field of healthcare contained in the state register of mandatory requirements were used. The requirements of legislative and subordinate regulatory legal acts establishing the general goals of state control (supervision), as well as special goals and priorities taking into account the specifics of the healthcare sector were studied. Results and discussion: An analysis of the existing indicators of the risk of violations of mandatory requirements shows that they do not effectively correlate with national and international standards in the field of healthcare and opens up significant prospects for their further improvement and modernization. Improvement of the system may be aimed at establishing a closer link between the signs of possible violations and the target control settings. This approach will ensure the systematic organization of priority areas for the development of new risk indicators while ensuring their compliance with the national health development goals of the Russian Federation. The implementation of this methodology will make it possible to effectively structure and prioritize development efforts, while maintaining a clear focus on achieving strategic goals in the healthcare sector. It seems advisable to develop a separate goal setting for state control (supervision) in the field of healthcare, as well as federal state control of the quality and safety of medical activities, and to establish as one of the goals of this control an increase in the population and strengthening the health of citizens, which directly reflects the effectiveness of the national health system. Conclusions: The proposed strategy not only contributes to the creation of new risk indicators, but also ensures their direct contribution to the implementation of national health goals, thereby increasing the overall effectiveness of the development process.

Volgograd Journal of Medical Research. 2026;23(1):13-19
pages 13-19 views
Digital transformation of healthcare through the formation of a unified medical information system
Akulin I.M., Platonov I.N., Sergienko A.Y.
Abstract

The digital transformation of healthcare is an urgent necessity, the key instrument of which is the creation of a unified medical information and analytical system. The relevance of the study is due to the fragmentation of existing IT-solutions in the industry, which reduces the effectiveness of interaction between institutions and the quality of medical care. Purpose: The study of the current state of the implementation of information systems in public medical organizations and the analysis of the regulatory framework for the digital transformation of healthcare in St. Petersburg. Materials and methods: The research material was data on the implementation of medical information systems in 241 medical organizations in St. Petersburg of federal and municipal ownership. Descriptive statistics, comparative analysis, and visualization methods were used to process the data, with an emphasis on the structure and prevalence of various systems. Results and discussion: The study revealed the use of 15 major information systems with a high degree of heterogeneity. The most common systems are Ariadna (31.5 % of institutions), WEB-polyclinic (16.2 %) and SP Samson (14.1 %). At the same time, a significant number of systems are used by individual institutions (0.4 % each), which indicates a pronounced fragmentation of the IT infrastructure. Conclusion: The analysis confirms the need to consolidate disparate information systems into a single digital platform as part of the implementation of national projects ("National Digital Platform "Health"). Successful digital transformation of the region's healthcare requires an in-depth analysis of the economic indicators and clinical effectiveness of the systems being implemented, improving the digital literacy of medical professionals, and ensuring the integration of existing information systems. This will create an integrated digital platform for improving the effectiveness of medical care.

Volgograd Journal of Medical Research. 2026;23(1):20-25
pages 20-25 views
Dynamics of changes in the condition of patients with temporomandibular joint pain dysfunction syndrome during complex treatment using dynamic electrical nerve stimulation
Eremin A.V., Konnov V.V., Averina K.M., Lykov A.A.
Abstract

When diagnosing and treating patients with temporomandibular joint pain dysfunction syndrome, it is necessary to examine the masticatory muscles and determine the nature and severity of pain. Purpose: To evaluate the dynamics of changes in the functional state of the masticatory muscles and pain symptoms during the comprehensive treatment of patients with temporomandibular joint pain dysfunction syndrome, including dynamic electrical nerve stimulation in the comprehensive treatment plan. Materials and methods: The study involved 60 patients with temporomandibular joint pain dysfunction syndrome and 30 of healthy control group. All of them underwent an examination, including electromyography and a visual analog pain scale to assess the condition of the masticatory muscles. The patients were then divided into two groups of 30. The first group was prescribed complex treatment with dynamic electrical neurostimulation therapy only on demand in the area of complaints, for patients of the second group dynamic electrical neurostimulation was carried out in a course of 10–15 sessions in the projection of complaints. The examination was repeated immediately after the end of treatment, 6 and 12 months thereafter. Results and discussion: We found that both groups of patients were cured or showed improvements compared to the condition before treatment (p < 0,001), the average electromyography values of the study groups were close to the average values of the control group. However, patients of the second group had more stable indicators when assessing the long-term treatment results. The values of the maximum amplitudes of muscle bioelectrical activity in some patients of the first group returned to increased values, the average values were significantly different from the average values of the control group. Conclusion: Based on the study, we can conclude that dynamic electrical stimulation has a positive effect on the condition of the masticatory muscles, eliminates pain, but with only a single use of this technique, stable values of muscle bioelectrical activity are not established, and the pain returns. Therefore, the use of dynamic electrical nerve stimulation is recommended in a comprehensive manner.

Volgograd Journal of Medical Research. 2026;23(1):26-35
pages 26-35 views
Evaluation of the state of local immunity of the oral cavity in patients before and after removal of impacted lower third molars
Makedonova Y.A., Medko N.A., Yarygina E.N., Fomichev E.V., Makedonova D.M.
Abstract

The problem of antibiotic-resistant bacteria poses serious challenges for modern surgical dentistry, particularly in preventing purulent complications after the removal of impacted lower third molars. In response to this challenge, bacteriophages are being actively studied worldwide as one of the most promising solutions. Bacteriophages have the potential to effectively eliminate antibiotic-resistant bacteria, demonstrate a high safety profile, and offer a wide range of therapeutic applications. Purpose: Determination of the effect of complex antibiotic and phagotherapy on local immunity indicators in patients who underwent extraction of retained lower third molars. Materials and methods: The study involved 60 patients with retained lower third molars. After surgery, the patients were randomized into two groups: the first group (30 patients) received antibiotics to prevent complications, while the second group (30 patients) received a combination of antibiotics and polyvalent pyobacteriophage. To assess the dynamics of the immune response in the oral cavity, the levels of pro-inflammatory and anti-inflammatory cytokines, as well as immunoglobulins of classes A, G, and M, were measured before and 10 days after surgery. The obtained results were processed in accordance with medical statistics requirements using nonparametric analysis methods. Quantitative variables were assessed using the Mann-Whitney U-test (for independent samples) or the Wilcoxon T-test for connected samples. Differences between groups were considered significant at p < 0.05. Results and discussion: The study revealed a decrease in the activity of inflammatory processes, which is confirmed by a decrease in the concentration of IL-1β and TNF in the oral fluid. At the same time, there was an increase in the anti-inflammatory response, which is manifested in an increase in the level of IL-10, as well as an activation of humoral immunity, which is expressed in an increase in the levels of IgA, IgG, and IgM. Conclusion: The obtained data indicate that the inclusion of bacteriophages in the therapeutic protocol of the postoperative period contributes to the positive modulation of the immune response in patients, demonstrating the beneficial effect of phage therapy on the immunological status in the postoperative period.

Volgograd Journal of Medical Research. 2026;23(1):36-46
pages 36-46 views
Features of GFAP expression in hippocampus of mature rats during modeling of type 1 diabetes mellitus and pharmacological correction
Smirnov A.V., Tyurenkov I.N., Pustynnikov V.E., Velikorodnaya Y.I., Petrov A.D.
Abstract

Investigation of the expression of glial fibrillary acidic protein (GFAP), a key marker of the functional state of astrocytes, in experimental modeling of diabetes mellitus (DM) is relevant due to the high incidence of diabetic encephalopathy in elderly patients with DM and the limited data on pathogenetic approaches to its therapy. Materials and methods: Using a model of type 1 DM induced by streptozotocin in 50 Wistar rats (aged 12 months), the effects of a 30-day course of aminalon (1000 mg/kg/day), succicard (50 mg/kg/day), and mefargin (20 mg/kg/day) were studied after 6 months of persistent hyperglycemia. GFAP expression in the hippocampus was assessed immunohistochemically followed by morphometry in ImageJ software and statistical analysis using ANOVA. Results and discussion: In the group of untreated diabetic animals, a significant decrease in the relative area of GFAP expression in hippocampal astrocytes was recorded compared to the intact control. Treatment with aminalon resulted in a larger area of immunoreactive material (IRM) in hippocampal neurons compared to diabetic animals. Animals receiving succicard also showed a larger area of IRM in hippocampal neurons compared to untreated diabetic animals. In diabetic animals treated with mefargin, a trend toward increased IRM was noted compared to material from untreated animals. Conclusion: Experimental DM leads to decreased GFAP expression in the hippocampus, indicating impaired astrocytic homeostasis and the involvement of glial cells in mechanisms of neuroinflammation in diabetic encephalopathy. GABA and its derivatives exert effects on astrocytes and promote the restoration of GFAP expression levels. The obtained results substantiate the promise of further investigation of GABA derivatives as agents for neuroprotection in cognitive disorders of diabetic origin.

Volgograd Journal of Medical Research. 2026;23(1):47-53
pages 47-53 views
Anatomical variants of the shape and size of the Turkish saddle on the lateral telerentgenogram and their significance in clinical practice
Krayushkin A.I., Samusev R.P., Dmitrienko A.D., Makedonova D.M.
Abstract

The variability of the shape and size of the Turkish saddle of the human sphenoid bone determines the relevance of the study, both from the point of view of morphology and clinical dentistry. Purpose: To determine the main variants of the shape and size of the Turkish saddle and to evaluate their significance in clinical diagnostic practice based on the analysis of lateral telerentgenograms. Materials and methods: 112 archived telerentgenograms images of young patients were analyzed. The study was retrospective and stratified. Generally accepted point landmarks were installed along all contours of the Turkish saddle, allowing measurements to be made in the sagittal and vertical directions. The modulus and index of the Turkish saddle were calculated, which made it possible to distribute the analyzed material into 3 groups. Results and discussion: The maximum height of the bone structure of the Turkish saddle was 11.8 mm, and the minimum was 6.09 mm. The front-rear size of the Turkish saddle ranged from 9.32 to 13.44 mm. The size of the entrance to the Turkish saddle ranged from 6.22 to 14.2 mm. Conclusion: The X-ray anatomical features of the Turkish sphenoid saddle are determined by its typological features. The basis for distinguishing the types of Turkish saddle can be the value of the index, determined by the ratio of height to sagittal size. With an index value from 0.67 to 0.87 c. u., the Turkish saddle can be classified as an average type. An increase of more than 0.88 indicates a high type of Turkish saddle, while a decrease (less than 0.66) indicates a low and wide type of Turkish saddle. The variability of the shape and size of the Turkish saddle can be used in clinical practice when analyzing lateral telerentgenograms to determine the most stable and well-projected point landmarks on the contours of the Turkish saddle.

Volgograd Journal of Medical Research. 2026;23(1):54-61
pages 54-61 views
Asymmetry of the forearm region in right-handed young adults: analysis by the method of geometric morphometry
Bakhmatov D.N., Dovgyallo Y.V., Kalashnikova S.A., Krayushkin A.I.
Abstract

The study of the asymmetry of the human upper extremities remains an urgent problem of modern anthropology and biomechanics, as it reflects the interaction of the genetic features of the structure and functional specialization of the dominant arm. The forearm area is a key link in the kinematic chain of the upper limb, sensitive to the specifics of motor activity. Classical osteometric studies have shown pronounced directional asymmetry of the bones of the upper extremities in various human populations, however, a detailed analysis of the asymmetry of the contour of the forearm using geometric morphometry has been limited. Purpose: Comprehensive assessment of the areas of the right and left forearms in right-handed young adults using geometric morphometry methods, determination of patterns of morphological intra-individual variability of this area among the study participants. Materials and methods: The study involved 32 young adults (18–20 years old, 23 young women and 9 young men), all participants were right-handed. The forearm was photographed in a frontal projection. Along the contour of the forearm, 40 evenly spaced half-marks were placed, which were transformed into marks. Data processing was carried out in MorphoJ 1.07a using principal component analysis (PCA) and Procrustes ANOVA methods with an assessment of the effects of individual differences, asymmetry and their interaction, separately for the size (Centroid Size) and shape (Shape) of the contour. Results and discussion: Procrustes ANOVA revealed a statistically significant intra-individual asymmetry of the average contour size (F = 5.60; p = 0.0243), however, the analysis of directional asymmetry vectors showed small differences (F = 1.12; p = 0.2259), which suggests a fluctuating nature of variability in the aspect of the pure shape of the forearm. The absence of statistically significant intra-individual differences in the shape of the forearm area between the right and left sides (p = 0.2259), while there is a statistically significant difference in the conditional "average" size (centroid size) between them (p = 0.0243), is an important result indicating that morphological asymmetry in the study group is realized mainly through proportional modification of the size of anatomical structures, with minimal local deformations, which preserves the overall pattern of absolute shape for the right and left sides. However, this does not mean that there is no asymmetry in the shape of the forearm. On the contrary, it is present, but without a certain directional vector, representing non-systemic fluctuations (a significant percentage of the residual variance Ind × Side ≈ 15.7 %). Conclusion: Morphological asymmetry of the forearm area in right-handed young adults is realized mainly through a proportional increase in size without obvious directional local deformations of the shape. The fluctuating nature of the shape asymmetry indicates random variations in development.

Volgograd Journal of Medical Research. 2026;23(1):62-71
pages 62-71 views
A retrospective hygienic analysis of long-term changes in the content of benz(a)pyrene in the air basin of the cities of the Donetsk industrial region
Grishchenko S.V., Grishchenko I.I., Minenko E.F., Zyablitsev E.D., Pravodelov S.S.
Abstract

The air basin is the most important part of the environment, largely determining its quality and the degree of potential danger to public health. Benz(a)pyrene belongs, on the one hand, to the most common aeroplutants, and on the other, to the most toxic air pollutants, especially in technogenic regions such as Donbass. Purpose: To establish the current patterns of distribution of this xenobiotic in the air environment of cities in the Donetsk industrial region. Materials and methods: With the help of sanitary-hygienic and medical-statistical research methods for a 36-year time period (1985–2020), the potential of technogenic pollution of the atmosphere with benz(a)pyrene was determined, the features of its average long-term content in the atmospheric air of the eight largest cities of Donbass, as well as the patterns of long-term dynamics of this indicator. Results and discussion: The data obtained in the course of this study reflect the impact of hygienic features of industrial development and the main sources of technogenic release of BP into the air basin on the content of the analyzed xenobiotic in the atmosphere of populated areas, which is consistent with the results of other researchers who noted an increase in atmospheric concentrations of BP as the amount of hydrocarbon fuel burned increased in industrial enterprises and in heating systems of utilities. The greatest potential for technogenic pollution of the WS air basin is established in the largest industrial-urban agglomerations of the Central Donbass, in the structure of atmospheric emissions of which the maximum specific gravity (39.3–85.5 %), belongs to industries based on the combustion of large amounts of hydrocarbon fuel (ferrous metallurgy, chemistry, coke chemistry). Conclusion: The results obtained will further optimize the scheme of socio-hygienic monitoring, reduce the degree of contamination of the air environment by the studied aeroplutant and, thereby, reduce the carcinogenic load on the population of Central Donbass.

Volgograd Journal of Medical Research. 2026;23(1):72-78
pages 72-78 views
Assessment of the carcinogenic risk of the impact of emissions from burning coal rock dumps on population health
Sadekov D.R., Sochilin A.V., Kotov V.S.
Abstract

One of the most significant sources of environmental stress in regions with a developed coal mining industry is burning coal-fired dumps, which become a source of toxic substances into the atmosphere. Рurpose: of the study is to assess the carcinogenic risk to public health from emissions from burning coal-fired dumps of mine, Sverdlovsk, LNR. Material and methods: To determine the levels of pollution, maximum single samples were taken from the leeward side of the dump at a distance of up to 500 m (up to the regulatory boundary of the sanitary protection zone, zone I) and 500–1 000 m (zone II). In 2013, 5 352 and 82 100 people lived in these zones, respectively. The risk of environmental factors was assessed in accordance with R 2.1.10.3968–23. 2.1.10. Results and discussion: Arsenic, cadmium, nickel, and lead are the priority substances of carcinogenic risk for the health of the population of Sverdlovsk from atmospheric air pollution by emissions of burning carbonaceous dump. The levels of total carcinogenic risk, as well as the values of individual carcinogenic risk (CR) from atmospheric air pollution by districts of the city, have been established. The leading role in the formation of carcinogenic risk has been established for arsenic – 94.6–94.8 % depending on the distance to the source of emissions into the atmosphere. For lead, nickel, and cadmium, the individual carcinogenic risk level is within the acceptable (low) risk range, and there is a trend towards an increase in the background incidence rate at this risk level. Conclusions: The total carcinogenic risk level is characterized as high and unacceptable for working conditions and the general population. In the current environmental situation, an additional 698 cases of cancer are likely to be added to the background level. The individual carcinogenic risk (CR) from air pollution varied from 1.5 · 10-2 - 4.2 · 10-6 in different areas of the city. This indicator is high for arsenic in atmospheric air (1.5 · 10-3), and for lead, nickel, and cadmium, it is within the acceptable (low) risk range.

Volgograd Journal of Medical Research. 2026;23(1):79-85
pages 79-85 views
Main risk factors for emotional burnout in healthcare workers
Molodtsova I.A., Slivina L.P.
Abstract

One of the complex and urgent problems in modern Russia is the preservation of the health of the working population, including medical professionals, and the prevention of professional burnout, which can lead to decreased productivity and professional longevity. Рurpose: Тo analyze the main risk factors for the formation of professional emotional burnout of medical workers, including doctors of multidisciplinary polyclinics in modern conditions. Materials and methods: Sanitary-statistical, socio-hygienic, sanitary-epidemiological, and mathematical-statistical methods were used. To assess the signs of professional emotional burnout (PEB) in polyclinic doctors, a questionnaire was conducted using a traditional method with a standardized questionnaire based on the MBI test (K. Maslach, S. Jackson, adapted by N. E. Vodopyanova). The study involved 173 surgical doctors from polyclinics in Volgograd. The observation groups were formed based on the doctors' work experience through interviews. The data of a special assessment of working conditions were used to characterize the hygienic factors of the working environment and the work process of doctors in multidisciplinary polyclinics. Results and discussion: The dynamics of the prevalence of PEV among medical workers for the period 1980–2026 was analyzed, which allowed to identify 3 peaks of the increase in the prevalence of PEV among doctors: 2017–2018, 2019–2020, 2023–2024. The prevalence of professional emotional burnout among doctors of the surgical profile of multidisciplinary polyclinics of the city of Volgograd was analyzed. The features of the manifestations of PEV in doctors with different work experience were revealed: less than 5 years, 5–10 years, 10–15 years, 15–25 years, more than 25 years. The determinants of the formation of PEV were considered, and a formalized model was formed. The main controllable factors of the formation of PEV in healthcare workers, including doctors of multidisciplinary polyclinics, were identified. Conclusion: A high prevalence of emotional burnout was identified among doctors of multidisciplinary polyclinics, which is largely determined by the intensity of the work process. A possible confirmation of the significance of this factor is the sharp increase in cases of PEC among doctors against the backdrop of active digital transformation of the healthcare system (2017–2018), work in the context of the COVID-19 pandemic (2019–2020), and the modernization of primary healthcare (2023–2024). Special attention should be paid to doctors with up to 5 years and 20–25 years of experience when identifying PEC. Due to the ambiguity of the prevalence of PEB in different seniority groups, it is advisable to consider the entire complex of factors presented in the formalized model of determinants of professional emotional burnout of medical workers when assessing the risk of developing PEB.

Volgograd Journal of Medical Research. 2026;23(1):86-92
pages 86-92 views